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Advance of theragnosis biomarkers in lung cancer: from clinical to molecular pathology and biology

  
@article{JTD25843,
	author = {Christina Alidousty and Till Baar and Carina Heydt and Svenja Wagener-Ryczek and Anna Kron and Juergen Wolf and Reinhard Buettner and Anne Maria Schultheis},
	title = {Advance of theragnosis biomarkers in lung cancer: from clinical to molecular pathology and biology},
	journal = {Journal of Thoracic Disease},
	volume = {11},
	number = {1},
	year = {2018},
	keywords = {},
	abstract = {One distinct molecular subtype of non-small cell lung cancer (NSCLC) is defined by rearrangement of the anaplastic lymphoma kinase (ALK). The increasing knowledge over the last years has enabled the continuous improvement of ALK inhibitors; however, resistance in these patients remains a major concern. In this review, we summarize recent findings in ALK+-adenocarcinoma of the lung, highlighting the role of TP53 mutations in this specific cancer type and suggest new diagnostic strategies for the future, in order to improve patient’s outcome.},
	issn = {2077-6624},	url = {http://jtd.amegroups.com/article/view/25843}
}