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Ventilator-associated events: prevalence and mortality in Japan

	author = {Susumu Nakahashi and Hiroshi Imai and Hideaki Imanaka and Shinichiro Ohshimo and Tomoko Satou and Masanori Shima and Masami Yanagisawa and Chizuru Yamashita and Toru Ogura and Tomomi Yamada and Nobuaki Shime and for the VAEs Review Committee in the Japanese Society of Intensive Care Medicine  (JSICM)},
	title = {Ventilator-associated events: prevalence and mortality in Japan},
	journal = {Journal of Thoracic Disease},
	volume = {10},
	number = {12},
	year = {2018},
	keywords = {},
	abstract = {Background: In 2013, the Centers for Disease Control and Prevention (CDC) issued the concept of the ventilator-associated events (VAEs) as a quality indicator (QI) in the intensive care unit (ICU). A number of studies have been conducted in the United States and other Western countries to evaluate its practicality. However, information on VAEs in non-Western countries is scarce. The purpose of this preliminary study was to illuminate the incidence and associated mortality rate of VAEs in Japan, as a first step in the effort to determine its practicality.
Methods: We conducted a multi-center, retrospective review of patient medical record using VAEs surveillance algorithm. We analyzed 785 patients with ≥2 days of mechanical ventilator (MV), admitted to the ICU at seven urban hospital in Japan. The prevalence of VAEs, including its three subtypes, and in-ICU mortality were researched.
Results: Forty-nine VAEs were identified, affecting 5.7% of patients requiring MV for ≥2 days and 6.4 per 1,000 MV days. Mortality in those who developed VAEs was 42.9%, significantly higher than the rest of the cohort (vs. 15.4%, P},
	issn = {2077-6624},	url = {}