TY - JOUR AU - Nakahashi, Susumu AU - Imai, Hiroshi AU - Imanaka, Hideaki AU - Ohshimo, Shinichiro AU - Satou, Tomoko AU - Shima, Masanori AU - Yanagisawa, Masami AU - Yamashita, Chizuru AU - Ogura, Toru AU - Yamada, Tomomi AU - Shime, Nobuaki AU - Japanese Society of Intensive Care Medicine (JSICM), for the VAEs Review Committee in the PY - 2018 TI - Ventilator-associated events: prevalence and mortality in Japan JF - Journal of Thoracic Disease; Vol 10, No 12 (December 30, 2018): Journal of Thoracic Disease Y2 - 2018 KW - N2 - Background: In 2013, the Centers for Disease Control and Prevention (CDC) issued the concept of the ventilator-associated events (VAEs) as a quality indicator (QI) in the intensive care unit (ICU). A number of studies have been conducted in the United States and other Western countries to evaluate its practicality. However, information on VAEs in non-Western countries is scarce. The purpose of this preliminary study was to illuminate the incidence and associated mortality rate of VAEs in Japan, as a first step in the effort to determine its practicality. Methods: We conducted a multi-center, retrospective review of patient medical record using VAEs surveillance algorithm. We analyzed 785 patients with ≥2 days of mechanical ventilator (MV), admitted to the ICU at seven urban hospital in Japan. The prevalence of VAEs, including its three subtypes, and in-ICU mortality were researched. Results: Forty-nine VAEs were identified, affecting 5.7% of patients requiring MV for ≥2 days and 6.4 per 1,000 MV days. Mortality in those who developed VAEs was 42.9%, significantly higher than the rest of the cohort ( vs . 15.4%, P Conclusions: The prevalence of VAEs appears low in Japanese ICUs. Nonetheless, mortality was substantially higher in patients who developed VAEs. Although some potential indices of VAEs are suggested to serve as QIs, additional studies to elaborate its practicality would further be required. UR - https://jtd.amegroups.org/article/view/25987