TY - JOUR AU - Kang, Min Gyu AU - Kim, Kyehwan AU - Ju, Sunmi AU - Park, Hyun Woong AU - Lee, Seung Jun AU - Koh, Jin-Sin AU - Hwang, Seok-Jae AU - Hwang, Jin-Yong AU - Bae, Jae Seok AU - Ahn, Jong-Hwa AU - Jang, Jeong Yoon AU - Park, Yongwhi AU - Jeong, Young-Hoon AU - Kwak, Choong Hwan AU - Park, Jeong Rang PY - 2019 TI - Clinical efficacy of high-flow oxygen therapy through nasal cannula in patients with acute heart failure JF - Journal of Thoracic Disease; Vol 11, No 2 (February 26, 2019): Journal of Thoracic Disease Y2 - 2019 KW - N2 - Background: High-flow oxygen therapy through nasal cannula (HFNC) could reduce intubation rate and mortality rate among patients with acute respiratory failure. We evaluated the physiological responses and clinical outcomes of HFNC in patients with acute heart failure (AHF). Methods: A retrospective cohort analysis was performed in single medical tertiary center. Patients with AHF who had a progressive hypoxemia after oxygenation via facemask were divided into intubation group and HFNC group. We analyzed the physiological responses and in-hospital clinical outcomes between two groups. Results: Seventy-three patients of intubation group and 76 patients of HFNC group were included. Baseline characteristics were well-balanced between two groups. There were no differences in changes of mean arterial pressure, heart rate, and pulse oxygen saturation during the first 6 hours. Among HFNC group, 66 of 76 patients (86.8%) were successfully recovered from progressive hypoxemia without endotracheal intubation, and there were no differences in in-hospital clinical outcomes between two groups. Conclusions: This study showed HFNC group had a similar result of improvement of oxygen saturation and in-hospital clinical outcomes compared with intubation group in AHF. Present study supported HFNC could be considered as initial choice of oxygen therapy in selected patients of AHF. UR - https://jtd.amegroups.org/article/view/26695