TY - JOUR AU - Bertolaccini, Luca AU - Spaggiari, Lorenzo PY - 2019 TI - The radical approach to the oligometastatic not small cell lung cancer patient: which? how? when? where? JF - Journal of Thoracic Disease; Vol 11, Supplement 15 (September 29, 2019): Journal of Thoracic Disease Y2 - 2019 KW - N2 - In 1894, Halsted defined that a primary tumour spread first through lymphatics vessels to lymph nodes and then to distant organs. Hellman argued that cancer, even at the time of diagnosis, is a biologic variety from a local to systemic illness with several transitional states. Subsequently, in 1995, Hellman and Weichselbaum first suggested the oligometastatic theory, where the number of metastases should imitate the biologic behaviour of a tumour, determining the chance for potential therapeutic interventions (1). In the eighth edition of the TNM classification, intrathoracic metastatic disease recollects the M1a classification. UR - https://jtd.amegroups.org/article/view/29478