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Single-dose del Nido cardioplegia used in adult minimally invasive valve surgery

  
@article{JTD29482,
	author = {Haiyan Luo and Xiaomin Qi and Hui Shi and Hui Zhao and Chaoqi Liu and Hongsong Chen and Runsheng Peng and Zhangsheng Yu and Kejian Hu and Chunsheng Wang and Xin Li},
	title = {Single-dose del Nido cardioplegia used in adult minimally invasive valve surgery},
	journal = {Journal of Thoracic Disease},
	volume = {11},
	number = {6},
	year = {2019},
	keywords = {},
	abstract = {Background: To analyze the protective effect of single-dose del Nido cardioplegia (DNC) in adult minimally invasive valve surgery. 
Methods: From January to December 2017, 165 consecutive adult patients who underwent minimally invasive valve surgery by the same team of surgeons were divided into two cohorts based on the type of cardioplegia administered during surgery: (I) single-dose DNC (DNC group (n=76, male 41, female 35) used in patients from May to December, 2017 and (II) intermittent standard 4:1 blood cardioplegia based on St.Thomas solution (SBC group, n=89, male 45, female 44) used in patients from January to April, 2017. Preoperative baseline demographics, preoperative comorbidities, operative variables, postoperative complications, and patient outcomes were collected and compared between the two groups. 
Results: Preoperative characteristics were shown to be similar between the two groups before and after propensity matching. Patients in the DNC group required a significantly lower volume of cardioplegia. The volume of ultrafiltration in the DNC group was substantially higher than that in the SBC group. The spontaneous return of heartbeat rate in the DNC group was considerably higher than that in the SBC group (97.0% vs. 78.8%, P=0.006). The Euroscore II in the DNC group was markedly lower than that in the SBC group (2.00 vs. 3.00, P},
	issn = {2077-6624},	url = {http://jtd.amegroups.com/article/view/29482}
}