@article{JTD31001,
author = {Hongmei Ding and Xianghuai Xu and Siwan Wen and Yiming Yu and Jing Pan and Cuiqin Shi and Ran Dong and Zhongmin Qiu and Li Yu},
title = {Changing etiological frequency of chronic cough in a tertiary hospital in Shanghai, China},
journal = {Journal of Thoracic Disease},
volume = {11},
number = {8},
year = {2019},
keywords = {},
abstract = {Background: The frequency distributions of the etiologies of chronic cough have changed over time. This study aimed to investigate the changing etiological frequency of chronic cough in a tertiary hospital in Shanghai, China, and to explore the clinical significance.
Methods: Medical records of 1,311 patients with chronic cough who visit our hospital between January 2009 and December 2016 were retrospectively reviewed. The etiologies of chronic cough were identified according to a standardized step-by-step diagnostic protocol and the changes in the etiological frequency of chronic cough over the years were using the Chi-squared (ꭓ2) test.
Results: Cough variant asthma (CVA) (449/1,311, 34.2%), gastroesophageal reflux-related chronic cough (GERC) (374/1,311, 28.5%), upper airway cough syndrome/postnasal drip syndrome (UACS/PNDs) (241/1,311, 18.4%), atopic cough (AC) (188/1,311, 14.3%), and non-asthmatic eosinophilic bronchitis (NAEB) (147/1,311, 11.2%) were the common causes of chronic cough in descending order. The post-infectious cough (PIC) (39/1,311, 3.0%) and angiotensin-converting enzyme inhibitor (ACEI)-induced cough (25/1,311, 1.9%) were less common. During the 8-year period, the proportion of CVA (ꭓ2=72.86, P},
issn = {2077-6624}, url = {https://jtd.amegroups.org/article/view/31001}
}