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Adjuvant chemotherapy for poor pathologic response after pre-operative chemoradiation in esophageal cancer: infeasible and illogical

   
@article{JTD31350,
	author = {Megan Greally and Geoffrey Y. Ku},
	title = {Adjuvant chemotherapy for poor pathologic response after pre-operative chemoradiation in esophageal cancer: infeasible and illogical},
	journal = {Journal of Thoracic Disease},
	volume = {11},
	number = {Suppl 15},
	year = {2019},
	keywords = {},
	abstract = {While recent decades have seen incremental improvements in the treatment of esophageal carcinoma, outcomes remain modest. The five-year overall survival (OS) rate for locally advanced esophageal cancer with surgery alone is 23–33% in contemporary studies (1-3). In locally advanced esophageal cancer, the risk of incomplete (R1) resection, local recurrence and systemic dissemination is significant. Numerous studies have demonstrated that the addition of chemotherapy and/or radiation to surgery improve outcomes, leading to multimodal treatment becoming standard-of-care. In particular, pre-operative chemoradiation has emerged as a standard-of-care in the US and Western Europe (4).},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/31350}
}