%0 Journal Article %T Clinicopathological characteristics and prognosis of lung cancer in young patients aged 30 years and younger %A Li, Fang %A He, Huayu %A Qiu, Bin %A Ji, Ying %A Sun, Kelin %A Xue, Qi %A Guo, Wei %A Wang, Dali %A Zhao, Jun %A Mao, Yousheng %A Mu, Juwei %A Gao, Shugeng %J Journal of Thoracic Disease %D 2019 %B 2019 %9 %! Clinicopathological characteristics and prognosis of lung cancer in young patients aged 30 years and younger %K %X Background: Lung cancer is one of the most common malignant tumors in the world and mainly occurs in elderly patients, but rarely in young patients. The purpose of this retrospective study was to examine the clinicopathological features and prognosis of lung cancer patients aged 30 years and younger. Methods: Patients aged 30 years and younger with lung cancer admitted to our center from November 2013 to October 2018 were retrospectively identified. Data included sex, age, smoking history, family history of cancer, high resolution computed tomography results, size and location of tumors, histology of tumors, lymph node status, stage of tumors, treatment methods and prognosis of patients. Results: The patient group included more females (56.3%) than males (43.7%) among lung cancer patients aged 30 and younger. Some patients had a history of tobacco inhalation and family cancer (17.5% and 22.3%, respectively). The most common tumors were in the left lower lobe (27.2%). Nearly half (49.5%) of the patients had pathological adenocarcinomas and 59.3% of the patients were showed early clinical stage and had no lymph node metastasis. All patients received surgical treatment; 47.1% received lobectomy and only 17.9% received adjuvant therapy such as radiotherapy, chemotherapy or targeted therapy after operation. Only seven (7.4%) of the successful follow-up patients died. Local recurrence occurred in two cases and distant metastasis in six cases. Conclusions: The main clinicopathological type of lung cancer in young lung cancer patients aged 30 years and younger is adenocarcinoma, and most cases were at the early stage. Surgical treatment based on lobectomy is still the main treatment method and the prognosis of these patients is very good. Early screening of lung cancer should be actively promoted for young people. %U https://jtd.amegroups.org/article/view/32452 %V 11 %N 10 %P 4282-4291 %@ 2077-6624