TY - JOUR AU - Gong, Wenhui AU - Ye, Xiaofeng AU - Shi, Kaihu AU - Zhao, Qiang PY - 2014 TI - Primary malignant pericardial mesothelioma—a rare cause of superior vena cava thrombosis and constrictive pericarditis JF - Journal of Thoracic Disease; Vol 6, No 12 (December 31, 2014): Journal of Thoracic Disease Y2 - 2014 KW - N2 - Primary malignant pericardial mesothelioma (PMPM) is an extremely rare, highly lethal and often misdiagnosed tumor. We report a 60-year-old woman complaining of dry cough, shortness of breath and exertional dyspnea due to a large pericardial effusion. The pericardial fluid volume declined after pericardiocentesis; analysis of the fluid revealed malignant cells and was negative for tuberculosis. Subsequently, the patient developed a compression of the superior vena cava and pericardial constriction. The patient’s symptoms marginally improved after partial pericardiectomy, and a diagnosis of pericardial mesothelioma was made on pathology. However, her symptoms continued to aggravate, and she died 8 months after presentation. Pericardial mesothelioma should be discovered earlier to treat patients who develop repeatedly pericardial effusion after pericardiocentesis and pericardial tamponade or those develop constrictive pericarditis. UR - https://jtd.amegroups.org/article/view/3532