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Restrictive pulmonary deficit is associated with inflammation in suboptimally controlled obese diabetics

  
@article{JTD454,
	author = {Lexley M. Pinto Pereira and Terence A. R. Seemungal and Surujpal Teelucksingh and B. Shivananda Nayak},
	title = {Restrictive pulmonary deficit is associated with inflammation in suboptimally controlled obese diabetics},
	journal = {Journal of Thoracic Disease},
	volume = {5},
	number = {3},
	year = {2012},
	keywords = {},
	abstract = {Caribbean data linking inflammation, pulmonary dysfunction and diabetes is unavailable. Spirometry, acanthosis nigricans, hs-CRP were assessed in 109 type 2 diabetics (43% males) mean age =55.6 years, BMI =29.29 kg/m2, waist circumference =103.86 cm. Residual FEV1/FVC increased with age (P=0.005), BMI (P=0.011) and waist circumference (P=0.003). Residual FVC related inversely to hs-CRP (–0.178), P<0.06) systolic (–0.028, P<0.031), diastolic (–0.247, P<0.010) pressure and weight (–0.25, P<0.009). Residual FEV1 related inversely to diastolic pressure (–0.219, P<0.023), hs-CRP (–0.234, P<0.015), acanthosis nigricans (–0.029, P<0.029). HbA1C and residual FEV1 predict high hs-CRP (P=0.011, P=0.046). Low FVC with inflammation presents in poorly controlled obese diabetics.},
	issn = {2077-6624},	url = {http://jtd.amegroups.com/article/view/454}
}