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History of pneumonia is a strong risk factor for chronic obstructive pulmonary disease (COPD) exacerbation in South Korea: the Epidemiologic review and Prospective Observation of COPD and Health in Korea (EPOCH) study

  
@article{JTD6115,
	author = {Yong Il Hwang and Sang Haak Lee and Jee Hong Yoo and Bock Hyun Jung and Kwang Ha Yoo and Moon Jun Na and Jong Deog Lee and Myung Jae Park and Chi Young Jung and Jae Jeong Shim and Kyung Chan Kim and Yeon Jae Kim and Hye Sook Choi and Ik Su Choi and Choon-Taek Lee and Sang Do Lee and Do Jin Kim and Soo-Taek Uh and Ho Sung Lee and Young Sam Kim and Kwan Ho Lee and Seung Won Ra and Hak Ryul Kim and Soo Jeon Choi and In Won Park and Yong Bum Park and So Young Park and Jaehee Lee and Ki-Suck Jung},
	title = {History of pneumonia is a strong risk factor for chronic obstructive pulmonary disease (COPD) exacerbation in South Korea: the Epidemiologic review and Prospective Observation of COPD and Health in Korea (EPOCH) study},
	journal = {Journal of Thoracic Disease},
	volume = {7},
	number = {12},
	year = {2015},
	keywords = {},
	abstract = {Background: In South Korea, chronic obstructive pulmonary disease (COPD) is one of the ten leading causes of death. COPD exacerbations are significantly associated with mortality in COPD patients. This study was conducted to investigate the epidemiology of COPD in South Korea, specifically the clinical characteristics of South Korean COPD patients, the COPD exacerbation rate and the risk factors associated with COPD exacerbations.
Methods: This study covers a 2-year interval. One year was data collected retrospectively and the second year was prospectively obtained data.
Results: A total of 1,114 subjects were enrolled in the study. These subjects were observed for a period of 1 year from the enrollment, and a total of 920 subjects completed the study. A total of 1,357 COPD exacerbations occurred in 711 subjects (63.8%) out of the total of 1,114 subjects during the study period of 2 years. Multivariate logistic regression results showed that if patients had had a pneumonia before the retrospective year of analysis, they had a 18 times greater chance of having an exacerbation during the prospective year when other variables were controlled. Also, the subjects who had a history of two or more exacerbations during the retrospective year were approximately 6 times more likely to experience the COPD exacerbation compared to those who did not.
Conclusions: This study examined the demographic and clinical characteristics of South Korean COPD patients and found that a history of pneumonia and two or more occurrences of exacerbation within 1 year was significantly associated with a higher rate of COPD exacerbation.},
	issn = {2077-6624},	url = {http://jtd.amegroups.com/article/view/6115}
}