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The surprising outcome of a giant primary mediastinal synovial sarcoma treated with neoadjuvant chemotherapy

  
@article{JTD816,
	author = {Marcos Alexandre Balieiro and Agnaldo José Lopes and Bruno Pinheiro Costa and Gustavo Perissé Moreira Veras and Paulo Sergio Perelson and Rodolfo Acatauassú Nunes and Eduardo Haruo Saito},
	title = {The surprising outcome of a giant primary mediastinal synovial sarcoma treated with neoadjuvant chemotherapy},
	journal = {Journal of Thoracic Disease},
	volume = {5},
	number = {1},
	year = {2013},
	keywords = {},
	abstract = {There are only a few cases of primary mediastinal synovial sarcoma in the literature. Normally, they do not respond well to chemotherapy. In our case, a 30-year-old patient was admitted due to thoracic pain, dyspnea, orthopnea, cough, hoarseness and weight loss over a 3-month period as well as a dramatic worsening a week before the admission. A chest radiography showed a completely white left hemithorax and contralateral mediastinal shift; in addition, a chest tomography revealed a giant heterogeneous mediastinal mass, lung atelectasia and a small pleural effusion. The patient was submitted to Chamberlain procedure (biopsy) under local anesthesia and the diagnosis of a synovial sarcoma was obtained after immunohistochemical analysis. Due to his poor general condition, he received chemotherapy first, with a dramatic response, after what, the mass that had been reduced was removed surgically. After a 5-year- follow-up period there are no signs of disease recurrence.},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/816}
}