@article{JTD9962,
author = {Ahmed Farouk and Mohammed H. Hassan and Mohammed Alaa Nady and Mohammed Farouk Abdel Hafez},
title = {Role of oxidative stress and outcome of various surgical approaches among patients with bullous lung disease candidate for surgical interference},
journal = {Journal of Thoracic Disease},
volume = {8},
number = {10},
year = {2016},
keywords = {},
abstract = {Background: Bullous lung disease is characterized by formation of blebs, bullae and emphysema. We investigate the role of oxidative stress in the pathogenesis of bullous lung disease and compare between conventional thoracotomy versus video assisted thoracoscopic approach in surgical management of such patients.
Methods: This study was a prospective case control study and it was carried out on 21 patients (16 male and 5 females) with bullous lung disease selected as candidate for surgical interference. This was in addition to 21 apparently healthy age and sex matched subjects selected as control group. Plasma levels of α1-antitrypsin were estimated using commercially available ELISA assay kit, while plasma levels of malondialdehyde (MDA), β-carotene, vitamin A, vitamin C and vitamin E were estimated using spectrophotometric methods. Conventional thoracotomy approach was done in thirteen patients, while, videothoracoscopic approach was done in eight patients.
Results: There were significant higher plasma levels of MDA (P},
issn = {2077-6624}, url = {https://jtd.amegroups.org/article/view/9962}
}