Prime time for the sweet spot in timing of coronary invasive approach in patients with non-ST elevation myocardial infarction

Eliano P. Navarese, Bernhard Wernly, Michael Lichtenauer, Martino Pepe, Wojciech Wanha, Giuseppe Ferrante, Lara Frediani, Verena Veulemans, Tobias Zeus, Ralf Westenfeld, Christian Jung, Paul A. Gurbel


Acute coronary syndromes (ACS) continue to represent a major cause of morbidity and mortality worldwide. In the past decade data from the United States and Europe reported decreased incidence of ST-elevation myocardial infarction (STE-ACS) with an increase in non-ST-elevation myocardial infarction (NSTE-ACS) (1-3). As compared to STE-ACS patients, during initial admission, NSTE-ACS patients are at lower risk for death, but over time death rates become comparable with a trend towards increased mortality in the latter group (4). NSTE-ACS therefore constitutes a challenge in cardiology.