Society for Translational Medicine Expert Consensus on the prevention and treatment of postoperative pulmonary infection in esophageal cancer patients

Zhentao Yu, Shanqing Li, Deruo Liu, Lunxu Liu, Jianxing He, Yunchao Huang, Shidong Xu, Weimin Mao, Qunyou Tan, Chun Chen, Xiaofei Li, Zhu Zhang, Gening Jiang, Lin Xu, Lanjun Zhang, Jianhua Fu, Hui Li, Qun Wang, Lijie Tan, Danqing Li, Qinghua Zhou, Xiangning Fu, Zhongmin Jiang, Haiquan Chen, Wentao Fang, Xun Zhang, Yin Li, Ti Tong, Yongyu Liu, Xiuyi Zhi, Tiansheng Yan, Xingyi Zhang, Lei Gong, Hongdian Zhang, John B. Downs, Nestor Villamizar, Shugeng Gao, Jie He


Esophageal cancer is ranked as the malignant tumor with the 6th highest morbidity and mortality rate worldwide. Chinese people are prone to develop esophageal cancer, and the number of new cases that occur every year account for more than half of the esophageal cancer patients worldwide (1,2). Although reports have confirmed the effectiveness of chemoradiotherapy for esophageal cancer, esophageal resection remains the primary means of treatment. Anastomotic leaks and pulmonary complications are the most common postoperative complications of esophageal cancer and carcinoma of the gastric cardia. Pulmonary complications have become more noticeable (3) as the incidence of postoperative anastomotic fistula (8–15%) has decreased due to the improvement of surgical techniques, the use of disposable staplers, and the continuous improvement of postoperative nutritional support Cervical and upper thoracic esophageal cancer are associated with a higher risk for postoperative pulmonary infection.

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