Vol 8, No 9 (September 28, 2016): Journal of Thoracic Disease


A novel prognostic marker of non-small cell lung cancer: chromosome 9 open reading frame 86 (C9orf86)
Katsuhiro Yoshimura, Murat Osman, Yusuke Inoue, Takafumi Suda, Haruhiko Sugimura
Ventriculo-arterial coupling: the comeback?
Bernard Cholley, Arthur Le Gall
Aspirin before coronary artery surgery
William M. Whited, Erin M. Schumer, Mark S. Slaughter
Stenting or bypass surgery for unprotected left main coronary artery disease—still a long rally to go
Tzu-Hsien Tsai, Cheng-I Cheng
Fine-tuning treatment for patients with ST-elevation myocardial infarction
Feng Qian, Edward L. Hannan
Timing of renal replacement therapy in acute kidney injury—an issue of importance?
Melanie Meersch, Alexander Zarbock
SBRT versus lobectomy in stage I NSCLC: knowns, unknowns and its interpretation
Matthias Guckenberger
Transcatheter aortic valve implantation at institutions without cardiovascular surgery departments: many questions still linger before a paradigm shift
Chiara Fraccaro, Giuseppe Tarantini
The IASLC lung cancer staging project proposal for the classification of lung cancers with multiple pulmonary sites of involvement: the first step toward finding optimal treatment
Samuel S. Kim
Improving post-resection risk stratification in non-small cell lung cancer: ‘wit, whither wander you?’
Raymond U. Osarogiagbon
Region specific lung nodule management practice guideline
Scott Apperley, Stephen Lam
Stage I lung cancer—to operate or to radiate? that is the question
Boris Sepesi, David C. Rice, John V. Heymach, Ara A. Vaporciyan, Stephen G. Swisher
Losmapimod does not reduce cardiovascular events in patients with acute myocardial infarction
Wilbert S. Aronow, Ryan K. Kaple
Veno-arterial extracorporeal membrane oxygenation for acute myocardial infarction-associated cardiogenic shock: can we predict survival before decision of implantation?
Nicolas Persico, Jeremy Bourenne, Antoine Roch
Neither the maximum tumor size nor solid component size is prognostic in part-solid lung cancer: to be ground-glass opacity or not to be, is that really the question?
Kimihiro Shimizu, Yoichi Ohtaki, Seshiru Nakazawa, Akira Mogi, Hiroyuki Kuwano
Pharmacotherapy in acute respiratory distress syndrome—the long and winding road
Michael Mazzeffi
Reducing exposure to cardiovascular risk factors: the legacy of prevention
Benoit J. Arsenault, Rishi Puri
Response to perioperative statin therapy in cardiac surgery: a matter of race and timing?
Tyler P. Rasmussen, Prashant D. Bhave
Non-invasive mechanical ventilation in hypoxemic respiratory failure: Just a matter of the interface?
Onnen Moerer, Lars-Olav Harnisch
Very long-term follow-up for left main coronary artery stenting: a missing piece of the jigsaw puzzle
Yalcin Velibey, Tolga Sinan Guvenc, Ahmet Taha Alper
Circulating tumour DNA and resistance mechanisms during EGFR inhibitor therapy in lung cancer
Carles Escriu, John K. Field
Relapsed small-cell lung cancer: platinum re-challenge or not
Antonio Rossi
Protective role of the matricellular protein CCN3 in abdominal aortic aneurysm
Pavel Uhrin, Johannes M. Breuss
Dual inhibition of BRAF and MEK in BRAF-mutated metastatic non-small cell lung cancer
Young Hak Kim
Reconsidering lung cancer screening: is biannual screening possible?
Alberto Ruano-Ravina, Alberto Fernandez-Villar, Mariano Provencio-Pulla
Translation from the data of clinical trials to precision medicine: limitation of the current risk score for predicting coronary thrombosis and major bleeding
Jong-Hwa Ahn, Jeong Yoon Jang, Young-Hoon Jeong
IL-1 receptor antagonist in sepsis: new findings with old data?
David Grimaldi, Eduardo Wilfrido Goicoechea Turcott, Fabio Silvio Taccone
Dual bronchodilation and exacerbations of COPD
Mario Cazzola, Josuel Ora, Ermanno Puxeddu
From anatomy to lung cancer: questioning lobe-specific mediastinal lymphadenectomy reliability
Marc Riquet Marc Riquet, Ciprian Pricopi, Alex Arame, Françoise Le Pimpec Barthes
Does less equal more? The curious issue of small-sized lung cancer
Katarzyna Żanowska, Jarosław Kużdżał
Mitral valve prolapse: where is the missing link?
Clemence Antoine, Hector I. Michelena, Maurice Enriquez-Sarano
Continous renal replacement therapy and intermittent hemodialysis in acute kidney injury: equivalent or complementary?
R. T. Noel Gibney
Dealing with the critical care aftermath: where to from here?
Jennifer D. Paratz, Robert J. Boots
The good receipt for the kidneys: salty…but not too much
Stefano Romagnoli, Zaccaria Ricci
Has lobe-specific nodal dissection for early-stage non-small lung cancer already become standard treatment?
Tomohiro Maniwa, Ken Kodama
Transcatheter aortic valve replacement: favorable clinical outcomes support role in intermediate risk surgical patients
Ravilla Mahidhar, Jon R. Resar
Conservatism strikes back: later is better than earlier dialysis for acute kidney injury
Dana Bielopolski, Kamyar Kalantar-Zadeh
Percutaneous left atrial appendage closure: here to stay
Lim Eng, Jacqueline Saw
Annual or biennial lung cancer CT screening?
Niki Karachaliou, Aaron E. Sosa, Rafael Rosell

Original Article

Impact of intercostal paravertebral neurectomy on post thoracotomy pain syndrome after thoracotomy in lung cancer patients: a randomized controlled trial
Aris Koryllos, Astrid Althaus, Marcel Poels, Robin Joppich, Rolf Lefering, Frank Wappler, Wolfram Windisch, Corinna Ludwig, Erich Stoelben
Suppressive oligonucleotides inhibit inflammation in a murine model of mechanical ventilator induced lung injury
Julia Scheiermann, Dennis M. Klinman
Video-assisted thoracoscopic lobectomy: which is the learning curve of an experienced consultant?
Antonio Mazzella, Anne Olland, Pierre Emmanuel Falcoz, Stephane Renaud, Nicola Santelmo, Gilbert Massard
Efficacy of lymph node dissection during robotic-assisted lobectomy for non-small cell lung cancer: retrospective review of 159 consecutive cases
Frank O. Velez-Cubian, Kathryn L. Rodriguez, Matthew R. Thau, Carla C. Moodie, Joseph R. Garrett, Jacques P. Fontaine, Eric M. Toloza
Prognostic value of preoperative serum lactate dehydrogenase in thymic carcinoma
Zu-Yang Yuan, Shu-Geng Gao, Ju-Wei Mu, Qi Xue, You-Sheng Mao, Da-Li Wang, Jun Zhao, Yu-Shun Gao, Jin-Feng Huang, Jie He
A randomized, open, multicenter clinical study on the short course of intravenous infusion of 750 mg of levofloxacin and the sequential standard course of intravenous infusion/oral administration of 500 mg of levofloxacin for treatment of community-acquired pneumonia
Tiemei Zhao, Liang-An Chen, Ping Wang, Guizhen Tian, Feng Ye, Huili Zhu, Bei He, Baiying Zhang, Changzhou Shao, Zhijun Jie, Xiwen Gao, Dongxia Wang, Weidong Song, Zhijie Pan, Jin Chen, Xingyi Zhang, Zhancheng Gao, Ping Chen, Youning Liu
Suberoylanilide hydroxamic acid attenuates paraquat-induced pulmonary fibrosis by preventing Smad7 from deacetylation in rats
Shan-Shan Rao, Xiang-Yan Zhang, Ming-Jun Shi, Ying Xiao, Ying-Ying Zhang, Yuan-Yuan Wang, Chang-Zhi Zhang, Song-Jun Shao, Xin-Mei Liu, Bing Guo
Outcomes of different treatments on Takayasu’s arteritis
Yu Xiao, Jian Zhou, Xiaolong Wei, Yudong Sun, Lei Zhang, Jiaxuan Feng, Rui Feng, Zhiqing Zhao, Zaiping Jing
Video-assisted thoracic surgery compared with posterolateral thoracotomy for mediastinal bronchogenic cysts in adult patients
Chenglin Guo, Jiandong Mei, Chengwu Liu, Senyi Deng, Qiang Pu, Feng Lin, Lunxu Liu
Positive esophageal proximal resection margin: an important prognostic factor for esophageal cancer that warrants adjuvant therapy
Yun-Cang Wang, Han-Yu Deng, Wen-Ping Wang, Du He, Peng-Zhi Ni, Wei-Peng Hu, Zhi-Qiang Wang, Long-Qi Chen
Association of CHEK2 polymorphisms with the efficacy of platinum-based chemotherapy for advanced non-small-cell lung cancer in Chinese never-smoking women
Wen Xu, Di Liu, Yang Yang, Xi Ding, Yifeng Sun, Baohong Zhang, Jinfu Xu, Bo Su
Progastrin-releasing peptide as a diagnostic and therapeutic biomarker of small cell lung cancer
Hyung-Joo Oh, Ha-Young Park, Ki-Hyun Kim, Cheol-Kyu Park, Hong-Joon Shin, Jung-Hwan Lim, Yong-Soo Kwon, In-Jae Oh, Yu-Il Kim, Sung-Chul Lim, Young-Chul Kim, Soo-Hyun Kim, Myung-Geun Shin
Patient evaluation for rapid pleurodesis of malignant pleural effusions
Rebecca Krochmal, Chakravarthy Reddy, Lonny Yarmus, Neeraj R. Desai, David Feller-Kopman, Hans J. Lee
Cell block samples from endobronchial ultrasound transbronchial needle aspiration provide sufficient material for ancillary testing in lung cancer—a quaternary referral centre experience
Emily Hopkins, David Moffat, Ian Parkinson, Peter Robinson, Hubertus Jersmann, Brendan Dougherty, Mohammed I. Birader, Kate Francis, Phan Nguyen
The feasibility of molecular testing on cell blocks created from brush tip washings in the assessment of peripheral lung lesions
Asha Bonney, Michael Christie, Anne Beaty, Sebastian Lunke, Graham Taylor, Louis Irving, Daniel Steinfort
A convenient method for identifying a small pulmonary nodule using a dyed swab and geometric mapping
Mitsuhiro Kamiyoshihara, Takashi Ibe, Natsuko Kawatani, Fumi Ohsawa, Ryohei Yoshikawa, Kimihiro Shimizu
Clinicopathological characteristics and prognosis of non-lepidic invasive adenocarcinoma presenting as ground glass opacity nodule
Youngkyu Moon, Sook Whan Sung, Kyo Young Lee, Jae Kil Park
Treatment outcomes of patients with small cell lung cancer without prophylactic cranial irradiation
Masakuni Sakaguchi, Toshiya Maebayashi, Takuya Aizawa, Naoya Ishibashi, Tsutomu Saito
Prognostic value of immunohistochemical markers in malignant thymic epithelial tumors
Priska Leisibach, Didier Schneiter, Alex Soltermann, Yoshi Yamada, Walter Weder, Wolfgang Jungraithmayr
Primary pulmonary artery sarcoma: a close associate of pulmonary embolism—20-year observational analysis
Debabrata Bandyopadhyay, Tanmay S. Panchabhai, Navkaranbir S. Bajaj, Pradnya D. Patil, Matthew C. Bunte
Modern radiotherapy using image guidance for unresectable non-small cell lung cancer can improve outcomes in patients treated with chemoradiation therapy
Matthew P. Deek, Sinae Kim, Ning Yue, Rekha Baby, Inaya Ahmed, Wei Zou, John Langenfeld, Joseph Aisner, Salma K. Jabbour
Clinicopathological features and prognosis of primary pulmonary lymphoepithelioma-like carcinoma
Wen-Yang Jiang, Rui Wang, Xu-Feng Pan, Yu-Zhou Shen, Tian-Xiang Chen, Yun-Hai Yang, Jin-Cheng Shao, Lei Zhu, Bao-Hui Han, Jun Yang, Heng Zhao
The effectiveness of mediastinal lymph node evaluation in a patient with ground glass opacity tumor
Youngkyu Moon, Sook Whan Sung, Min Namkoong, Jae Kil Park
Correlation analysis of lung cancer and urban spatial factor: based on survey in Shanghai
Lan Wang, Xiaojing Zhao, Wangyue Xu, Jian Tang, Xiji Jiang
Efficiency and safety of roflumilast combined with long-acting bronchodilators on moderate-to-severe stable chronic obstructive pulmonary disease patients: a meta-analysis
Peng Luo, Shuo Li, Yitai Chen, Yuwen Luo, Yun Li, Kai Wang, Yuxia Huang, Xin Chen

Short Communication

Cardiogenic syncope possibly related to bevacizumab-containing combination chemotherapy for advanced non-small cell lung cancer
Haruka Chino, Yosuke Amano, Yasuhiro Yamauchi, Jun Matsuda, Norihiko Takeda, Goh Tanaka, Daiya Takai, Takahide Nagase


AME evidence series 001—The Society for Translational Medicine: clinical practice guidelines for diagnosis and early identification of sepsis in the hospital
Zhongheng Zhang, Nathan J. Smischney, Haibo Zhang, Sven Van Poucke, Panagiotis Tsirigotis, Jordi Rello, Patrick M. Honore, Win Sen Kuan, Juliet June Ray, Jiancang Zhou, You Shang, Yuetian Yu, Christian Jung, Chiara Robba, Fabio Silvio Taccone, Pietro Caironi, David Grimaldi, Stefan Hofer, George Dimopoulos, Marc Leone, Sang-Bum Hong, Mabrouk Bahloul, Laurent Argaud, Won Young Kim, Herbert D. Spapen, Jose Rodolfo Rocco

Case Report

Hybrid video-assisted thoracoscopic surgery lobectomy and en-bloc chest wall resection for non-small cell lung cancer
Edward J. Caruana, Pierogiorgio Solli, Aman S. Coonar
A giant pleural poorly differentiated synovial sarcoma (PDSS) in a 64-year-old woman
Mariusz Chabowski, Anna Szymańska-Chabowska, Dawid Janczak, Tadeusz Dorobisz, Michał Leśniak, Michal Jeleń, Dariusz Janczak
Unilateral absence of pulmonary artery associated with contralateral lung cancer
Liang-Ze Zhang, Wei-Guo Ma, Shu-Geng Gao, Jie He
Primary pulmonary chondrosarcoma and a fast-growing mass that accidentally mimicked teratoma
Jingjin Jiang, Qian Shen, Wei Ding, Jianying Zhou
Surgical management of very late paravalvular leaks after mitral valve replacement: a single institutional experience
Philip Y. K. Pang, Jiasi Zhu, Yoong Kong Sin, Yeow Leng Chua
Thick lung wedge resection for acute life-threatening massive hemoptysis due to aortobronchial fistula
Mayank Gupta, Yuichiro Ozawa, Tomomi Nakajima, Akihiko Ikeda, Taisuke Konishi, Kanji Matsuzaki
Extensive plastic bronchitis: etiology of a rare condition
Norbert Garcia-Henriquez, Eric M. Toloza, Farah Khalil, Maria F. Echavarria, Joseph R. Garrett, Carla C. Moodie, Frank J. Kaszuba, Jacques P. Fontaine
Uniportal video-assisted thoracoscopic right upper sleeve lobectomy and tracheoplasty in a 10-year-old patient
Diego Gonzalez-Rivas, Jessica Correa Marin, Juan Pablo Ovalle Granados, Juan David Urrea Llano, Sonia Roque Cañas, Alonso Oviedo Arqueta, Mercedes de la Torre
A case of anterior mediastinitis and bilateral multiple lung abscesses occurring after trans-subxiphoid video-assisted thoracoscopic extended thymectomy for thymoma with myasthenia gravis
Hanlu Zhang, Yingcai Geng, Yu Zheng, Yun Wang
Chronic suppurative lung disease in adults
Mark L. Metersky, Antranik Mangardich


Adjuvant vitamin C treatment in sepsis—how many oranges a day keep (vasopressor-dependent) septic shock away?
Patrick M. Honore, Rita Jacobs, Inne Hendrickx, Elisabeth De Waele, Herbert D. Spapen
Quick sequential organ failure assessment: big databases vs. intelligent doctors
Jean-Louis Vincent, David Grimaldi
Dexmedetomidine for hyperactive delirium: worth further study
Melissa P. Knauert, Margaret A. Pisani
Microsized lung adenocarcinoma vs. small-sized lung adenocarcinoma: clinical characteristics, advantages and surgical implications
Giuseppe Mangiameli, Pierfilippo Crucitti, Gaetano Rocco
Early or delayed initiation of renal replacement therapy for critically ill patients—do we know the right time?
Yohei Komaru, Kent Doi
Snapshots of CD4+ T cell plasticity in the pathogenesis of allergic asthma
Wook-Jin Chae, Alfred L. M. Bothwell
High-flow nasal cannula in postextubation management
Lu Chen, Hong-Liang Li, Laurent Brochard
Pioneers, sceptics and those who seek the truth
Joel Dunning
The quest for the optimal blood pressure in septic shock
Sahajal Dhooria, Inderpaul Singh Sehgal, Ritesh Agarwal
Coronary artery bypass grafting saves lives!
Benjamin Medalion, Soon J. Park
Aortic aneurysm, CCN3 may solve the problem
Yalin Emre, Beat A. Imhof
Systemic therapy for echinoderm microtubule-associated protein-like 4 anaplastic lymphoma kinase non-small cell lung cancer brain metastases
Jenny Guo, Ralph Zinner, Nicholas G. Zaorsky, Wei Guo, Bo Lu
The role of coronary artery bypass grafting in patients with ischemic cardiomyopathy in the current era
Takashi Murashita
Risk guided use of the direct thrombin inhibitor bivalirudin: insights from recent trials and analyses
William B. Hillegass, Gregory S. Bradford
Beta-blockers in patients with septic shock: plenty of promise, but no hard evidence yet
Won-Young Kim, Sang-Bum Hong
Quantitative computed tomography: what does airway obstruction look-like?
Maria Kallieri, Andriana I. Papaioannou, Konstantinos Kostikas, Petros Bakakos, Stelios Loukides
LATITUDE-TIMI: is there still hope for anti-inflammatory therapy in acute myocardial infaction?
Matthias Dewenter, Michael Wagner, Ali El-Armouche
Adenocarcinoma containing lepidic growth
Hisashi Iwata
Cardiovascular magnetic resonance, mitral regurgitation and outcomes: the importance of accurate assessment in an era of increasing intervention
Rebecca Kozor, Stuart Grieve, Gemma Figtree, Ravinay Bhindi
Shedding light on the mechanisms of stent thrombosis with optical coherence tomography
Johannes Nicolaas van der Sijde, Evelyn Regar
Early detection and early treatment of lung cancer: risks and benefits
Giulia Veronesi, Pierluigi Novellis, Emanuele Voulaz, Marco Alloisio
Statins for delirium in ICU patients: a negative trial but a positive step
Peter W. Lange, Andrea B. Maier
Early feeding after esophagectomy may be too early
Thomas A. D’Amico
Do p38 mitogen-activated protein kinase inhibitors have a future for the treatment of cardiovascular disease?
Andrew R. Kompa
Dexmedetomidine for agitated delirium in intensive care unit intubated patients
Stefano Busani, Cosetta Cantaroni, Massimo Girardis
Tiny lung adenocarcinomas: better prognosis with a word of caution
Ramón Rami-Porta
The necessity of mediastinal lymph node resection for screen-diagnosed non-small cell lung cancer (NSCLC) manifesting as subsolid nodule
Sukki Cho
Immunoproteasome deficiency in non-small cell lung cancer and its relevance to immunotherapy
Juergen Kast
Learning how to do esophagectomies
Katy A. Marino, Benny Weksler
Antiplatelet agents in out of hospital cardiac arrest survivors—does an impaired biological response increase stent thrombosis risk?
Antoinette Neylon, Philippe Garot
Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC) registry predicting predictors for aortic dissection: a new thought around the corner?
Giacomo Murana, Antonio Pantaleo, Alessandro Parolari, Roberto Di Bartolomeo, Davide Pacini


1. The series “Statistics Corner” was commissioned by the Editorial office, Journal of Thoracic Disease without any sponsorship or funding. Luca Bertolaccini served as the unpaid Guest Editor for the series.