Vol 12, Supplement 1 (February 2020): Journal of Thoracic Disease (Sepsis: Science and Fiction)

Review Article

Role of procalcitonin use in the management of sepsis
Claudia Gregoriano, Eva Heilmann, Alexandra Molitor, Philipp Schuetz
The complete blood count to diagnose septic shock
Joshua David Farkas
Driving blind: instituting SEP-1 without high quality outcomes data
Jeffrey Wang, Jeffrey R. Strich, Willard N. Applefeld, Junfeng Sun, Xizhong Cui, Charles Natanson, Peter Q. Eichacker
Fluid resuscitation in sepsis: the great 30 mL per kg hoax
Paul E. Marik, Liam Byrne, Frank van Haren
The origins of the Lacto-Bolo reflex: the mythology of lactate in sepsis
Rory Spiegel, David Gordon, Paul E. Marik
Melatonin for the treatment of sepsis: the scientific rationale
Ruben Manuel Luciano Colunga Biancatelli, Max Berrill, Yassen H. Mohammed, Paul E. Marik
Timeliness of antibiotics for patients with sepsis and septic shock
Michiel Schinkel, Rishi S. Nannan Panday, W. Joost Wiersinga, Prabath W. B. Nanayakkara
Early norepinephrine use in septic shock
Olfa Hamzaoui, Rui Shi
Thiamine (vitamin B1) in septic shock: a targeted therapy
Ari Moskowitz, Michael W. Donnino
Vitamin C: an essential “stress hormone” during sepsis
Paul E. Marik
Sepsis trends: increasing incidence and decreasing mortality, or changing denominator?
Chanu Rhee, Michael Klompas
Time to stop randomized and large pragmatic trials for intensive care medicine syndromes: the case of sepsis and acute respiratory distress syndrome
Armand R. J. Girbes, Harm-Jan de Grooth


This supplement “Sepsis: Science and Fiction” was commissioned by the Editorial office, Journal of Thoracic Disease without any sponsorship or funding. Paul E. Marik served as the unpaid Guest Editor for the supplement.