%0 Journal Article %T Tocopherols and tocotrienols as anticancer treatment for lung cancer: future nutrition %A Zarogoulidis, Paul %A Cheva, Aggeliki %A Zarampouka, Katerina %A Huang, Haidong %A Li, Chen %A Huang, Yong %A Katsikogiannis, Nikolaos %A Zarogoulidis, Konstantinos %J Journal of Thoracic Disease %D 2013 %B 2013 %9 %! Tocopherols and tocotrienols as anticancer treatment for lung cancer: future nutrition %K %X Nutrition has been known for ages to shield the immune system against several formulations that deregulate normal DNA repair mechanisms, and induce tumorigenesis. Vitamins and in specific Vit E and its members tocopherols (α-, β-, γ-, δ-) and tocotrienols (α-, β-, γ-, δ-) have demonstrated strong association with the prevention of cancer and inhibition of tumor, both in vitro and in vivo. Vitamin E has also demonstrated effective role against chemotherapy resistant cancer cell evolution and a protective role in acute interstitial disease. Several formulations of Vitamin E have been investigated conjugated with different carriers as nano-formulations and administered in different forms. Additionally, several tumorigenic pathways have been investigated separately in an effort to identify which member of Vitamin E inhibits efficiently every pathway. Vitamin E presented efficiency against specific subhistology types of lung cancer. Finally, in the current work up to date information regarding novel formulations with Vitamin E and inhibition pathways are going to be presented and commented. %U https://jtd.amegroups.org/article/view/1045 %V 5 %N 3 %P 349-352 %@ 2077-6624