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A population-based analysis of outcomes after radiotherapy in intensive care unit patients with lung cancer

  
@article{JTD19468,
	author = {Alexander V. Louie and Lihua Li and Krista Bray Jenkyn and Britney Allen and George B. Rodrigues and Andrew Warner and David A. Palma and Salimah Z. Shariff},
	title = {A population-based analysis of outcomes after radiotherapy in intensive care unit patients with lung cancer},
	journal = {Journal of Thoracic Disease},
	volume = {10},
	number = {3},
	year = {2018},
	keywords = {},
	abstract = {Background: As the value of radiotherapy (RT) in intensive care unit (ICU) patients with lung cancer is of uncertain efficacy, we evaluated characteristics, outcomes and RT utilization for such patients in Ontario, Canada. 
Methods: Multiple administrative databases were linked deterministically using unique encoded identifiers to identify eligible patients between April 1, 2007, and March 31, 2014. Differences in patient, treatment, institution and tumor characteristics between RT and non-RT groups at the level of episode of care were compared. Overall survival (OS) was evaluated using the Kaplan-Meier method, with differences compared using the log-rank test. Univariable and multivariable Cox proportional hazard modeling were performed to assess the effect of RT on survival. 
Results: RT was delivered in 133 episodes of care to 1.0% (n=131) of the 13,739 unique patients with lung cancer. RT delivery was associated with younger age (median 65 vs. 68, P},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/19468}
}