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Prognostic value of pre-transplant mean pulmonary arterial pressure in lung transplant recipients: a single-institution experience

  
@article{JTD19662,
	author = {Chi Young Kim and Ji Eun Park and Ah Young Leem and Joo Han Song and Song Yee Kim and Kyung Soo Chung and Eun Young Kim and Ji Ye Jung and Young Ae Kang and Young Sam Kim and Joon Chang and Jin Gu Lee and Hyo Chae Paik and Moo Suk Park},
	title = {Prognostic value of pre-transplant mean pulmonary arterial pressure in lung transplant recipients: a single-institution experience},
	journal = {Journal of Thoracic Disease},
	volume = {10},
	number = {3},
	year = {2018},
	keywords = {},
	abstract = {Background: Currently, lung transplantation (LTX) is considered to be a curative treatment option in patients with end-stage lung disease. Although pulmonary hypertension (PH), confirmed by cardiac catheterization, is a prognostic factor in patients undergoing LTX, the prognostic value of PH in Asian lung transplant recipients remains uncertain. In this study, we aimed to determine whether PH before LTX may serve as a prognostic factor for survival in Asian patients. 
Methods: The medical records of 50 patients [male, 27; female, 23; mean age, 51.0 (41.0–60.0) years], who received preoperative right heart catheterization (RHC) and echocardiography before single or double LTX at Severance Hospital between January 2010 and December 2014, were reviewed. The relationship between 1-year survival after LTX and PH [mean pulmonary arterial pressure (mPAP) ≥25 mmHg at rest] was evaluated. 
Results: The mean right ventricular systolic pressure and mPAP were 48.5 (22.8) and 30.0 (24.0–40.0) mmHg. Of the 50 patients, 17 (34.0%) died within a year after LTX. The 1-year survival rate among patients with mPAP ≥25 mmHg (58.8%) was lower than the survival rate among patients with mPAP },
	issn = {2077-6624},	url = {https://jtd.amegroups.com/article/view/19662}
}