TY - JOUR AU - Shehada, Sharaf-Eldin AU - Wendt, Daniel AU - Peters, Davina AU - Mourad, Fanar AU - Marx, Philipp AU - Thielmann, Matthias AU - Kahlert, Philipp AU - Lind, Alexander AU - Janosi, Rolf-Alexander AU - Rassaf, Tienush AU - Rath, Peter-Michael AU - Thoenes, Martin AU - Jakob, Heinz AU - El Gabry, Mohamed PY - 2018 TI - Infections after transcatheter versus surgical aortic valve replacement: mid-term results of 200 consecutive patients JF - Journal of Thoracic Disease; Vol 10, No 7 (July 31, 2018): Journal of Thoracic Disease Y2 - 2018 KW - N2 - Background: Transcatheter aortic valve implantation (TAVI) is the standard therapy for high-risk patients with aortic stenosis (AS). TAVI-outcomes are widely investigated in comparison to surgical aortic valve replacement (SAVR), but less is known about infectious complications after TAVI. We aimed to compare early and mid-term infectious outcomes of patients undergoing TAVI or SAVR. Methods: The present study is a prospective single-centre study including 200 consecutive patients between 06/2014–03/2015 undergoing TAVI (either transfemoral or transapical and transaortic, n=47+53=100) or SAVR (either isolated or concomitant with CABG, n=52+48=100). The mean age and log. EuroSCORE were significantly different between both groups (81±6 versus 69±11 years, P Results: Primary endpoints showed no difference in overall TAVI- versus SAVR-groups regarding respiratory- (14% versus 19%, P=0.45), urinary-tract (7% versus 4%, P=0.54) infections, sepsis (5% versus 6%, P=1.0), endocarditis (0% versus 1%, P=1.0) or 30-day mortality (10% versus 4%, P=0.09), except for wound disorders, which were significantly lower in the TAVI-group (1% versus 8%, P=0.035), respectively. Secondary endpoints reported no difference regarding infectious related rehospitalisation (4% versus 4%, P=1.0), but significantly higher 2-year mortality (28% versus 16%, P=0.048) in the TAVI-group. Conclusions: So far, little has been studied about infectious complications after TAVI. This study reports no difference between the overall TAVI and SAVR groups regarding infectious complications. However, SAVR group show more wound healing disorders but less mortality than TAVI group. UR - https://jtd.amegroups.org/article/view/22530