%0 Journal Article %T Impact of the introduction of thoracoscopic lobectomy for non-small cell lung cancer: a propensity score-matched analysis %A Odaka, Makoto %A Noda, Yuki %A Tsukamoto, Yo %A Kato, Daiki %A Shibasaki, Takamasa %A Mori, Shohei %A Asano, Hisatoshi %A Matsudaira, Hideki %A Yamashita, Makoto %A Morikawa, Toshiaki %J Journal of Thoracic Disease %D 2018 %B 2018 %9 %! Impact of the introduction of thoracoscopic lobectomy for non-small cell lung cancer: a propensity score-matched analysis %K %X Background: The present study evaluated the impact of the introduction of thoracoscopic lung lobectomy (TL) for non-small cell lung cancer at our institution. Methods: This study retrospectively compared surgical and oncological outcomes in the period before and after the introduction of TL for non-small cell lung cancer. Propensity score-matched analysis was performed with respect to baseline patient variables and tumor characteristics. Results: Patients were divided into two groups: those who underwent lung lobectomy in the period before (BI group, n=261) and after (AI group, n=261) the introduction of TL. The proportion of TLs at our institution increased from 1.3% in the BI group to 93% in the AI group. The AI group experienced a longer duration of surgery, lesser intraoperative blood loss, and a significantly shorter postoperative hospital stay (POHS). There were no significant differences in postoperative complications between the two groups. The median follow-up period was 50 months in both groups. No significant differences were observed between the BI and AI groups with respect to 5-year overall survival (OS) (76.1% and 71.7%, respectively; P=0.1973) and disease-free survival (DFS) (67.6% and 66.1%, respectively; P=0.4071). On multivariate analysis, pathological N1–2 status was an independent predictor of survival. AI group and TL showed no independent association with survival. Conclusions: The introduction of TL represented a positive change at our institution owing to decreased invasiveness and oncological equivalence of the surgical treatment for non-small cell lung cancer. %U https://jtd.amegroups.org/article/view/23357 %V 10 %N 8 %P 4985-4993 %@ 2077-6624