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A leopard can’t change its spots: can a T790M mutation-positive cancer change its spots after epidermal growth factor receptortyrosine kinase inhibitor therapy?

   
@article{JTD24812,
	author = {Kai Obayashi and Kimihiro Shimizu and Seshiru Nakazawa and Yoichi Ohtaki and Natsuko Kawatani and Ibe Takashi and Toshiki Yajima and Akira Mogi and Ken Shirabe},
	title = {A leopard can’t change its spots: can a T790M mutation-positive cancer change its spots after epidermal growth factor receptortyrosine kinase inhibitor therapy?},
	journal = {Journal of Thoracic Disease},
	volume = {10},
	number = {Suppl 33},
	year = {2018},
	keywords = {},
	abstract = {Drug therapies for non-small cell lung cancer (NSCLC) have greatly progressed in recent years. Especially, the identification of epidermal growth factor receptor (EGFR) mutation has transformed the management of patients with EGFR-mutant NSCLC, who are sensitive to EGFR tyrosine kinase inhibitor (EGFR-TKI).},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/24812}
}