TY - JOUR AU - Esteller, Laura AU - Hernández, Susana AU - Lopez-Rios, Fernando AU - Remon, Jordi PY - 2018 TI - Could WNT inhibitors really knock on the treatment door of small cell lung cancer? JF - Journal of Thoracic Disease; Vol 11, Supplement 3 (March 12, 2019): Journal of Thoracic Disease Y2 - 2018 KW - N2 - Small cell lung cancer (SCLC) is an exceptionally lethal cancer for which new therapeutic approaches are needed. Despite over 30 years of clinical research, little progress has been made in the management of SCLC, and outcomes remain poor with median overall survival (OS) of 29 months with chemo-radiotherapy and prophylactic cranial irradiation in limited stage SCLC, and of 9–11 months in the metastatic setting with platinum-etoposide, even in the most recent randomized clinical trials with chemotherapy alone (1,2). UR - https://jtd.amegroups.org/article/view/25991