TY - JOUR AU - Milne, Stephen AU - King, Gregory G. PY - 2014 TI - Advanced imaging in COPD: insights into pulmonary pathophysiology JF - Journal of Thoracic Disease; Vol 6, No 11 (November 18, 2014): Journal of Thoracic Disease (Chronic Obstructive Pulmonary Disease) Y2 - 2014 KW - N2 - Chronic obstructive pulmonary disease (COPD) involves a complex interaction of structural and functional abnormalities. The two have long been studied in isolation. However, advanced imaging techniques allow us to simultaneously assess pathological processes and their physiological consequences. This review gives a comprehensive account of the various advanced imaging modalities used to study COPD, including computed tomography (CT), magnetic resonance imaging (MRI), and the nuclear medicine techniques positron emission tomography (PET) and single-photon emission computed tomography (SPECT). Some more recent developments in imaging technology, including micro-CT, synchrotron imaging, optical coherence tomography (OCT) and electrical impedance tomography (EIT), are also described. The authors identify the pathophysiological insights gained from these techniques, and speculate on the future role of advanced imaging in both clinical and research settings. UR - https://jtd.amegroups.org/article/view/3481