Temperature and duration targets during post-arrest care: choosing the right prescription for the right patient

John C. Greenwood, Abhishek Bhardwaj, Benjamin S. Abella


Targeted temperature management (TTM) was established as a key post-arrest therapy after the publication of two randomized trials in 2002 (1,2). Both trials showed improvement in favorable neurologic outcomes characterized by Cerebral Performance Categories (CPC) score of 1–2 and a lower 6-month mortality with the use of TTM after out-of-hospital cardiac arrest (OHCA) from ventricular fibrillation or ventricular tachycardia (VF/VT).

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