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Prolonged air leak after lung surgery: prediction, prevention and management

This special Series, “Prolonged Air Leak After Lung Surgery: Prediction, Prevention and Management”, published in the Journal of Thoracic Disease, aims to present readers with an extensive update on the PAL. We asked each expert to analyze specific aspects by sharing their experience and expertise, such as PAL after robotic surgery and segmentectomy. We have also analyzed the economic impact of PAL through the cost analysis of new devices and complications. Readers can find other interesting insights.

Join us at the 103th Annual Meeting of American Association for Thoracic Surgery (AATS)

The 103th Annual Meeting of American Association for Thoracic Surgery (AATS) is going to be held at the Los Angeles Convention Center, Los Angeles, CA, USA, from May 6 to 9, 2023: https://events.aats.org/am23.

This time, JTD as well as its sister journals and books published by AME Publishing Company will be on display during this exciting academic event! We would like to seize this great opportunity to meet our authors, editorial board members and readers.

Reviewer of the Month (2022)

In 2022, JTD reviewers continue to make outstanding contributions to the peer review process. They demonstrated professional effort and enthusiasm in their reviews and provided comments that genuinely help the authors to enhance their work.

New Impact Factor for Journal of Thoracic Disease: 3.005

We are pleased to announce that the Journal of Thoracic Disease (JTD) has attained its latest impact factor update for the 2021 citation year: 3.005.

Here, we would like to extend our heartfelt gratitude to all our Editorial Team Members, Guest Editors, authors, and reviewers for their valuable contributions.

Journal of Thoracic Disease (JTD) is now a member of Committee on Publication Ethics (COPE)

Starting from July 2021, AME Publishing Company is formally recognized a publisher member of Committee on Publication Ethics (COPE) and over 60 AME-published journals become a member of Committee on Publication Ethics (COPE), as part of AME’s commitment to best practice in scholarly publishing. Journal of Thoracic Disease (JTD) is among the list of COPE membership.

Lung Transplantation: Past, Present, and Future

Lung transplantation is the most viable option for many pulmonary diseases in appropriate candidates when medical therapy has failed. This series of manuscripts in this issue was planned prior to the pandemic. Donors remain rate-limiting and the field has been rapidly evolving with innovative approaches resulting in improved outcomes for recipients receiving grafts. The number of lung transplants for patients with COVID-related lung failure is increasing since the first one being performed in 2020. Since the planning of this issue we have been burdened with the COVID-19 pandemic and lung failure has become first and foremost in our lives.

Artificial Intelligence in Thoracic Disease: From Bench to Bed

We organized this special series to allow respiratory physicians and thoracic surgeons to better understand the artificial intelligence technology currently applied to thoracic diseases, grasp the cutting-edge artificial intelligence cross-research progress, and inspire more respiratory physicians and thoracic surgeons to participate in the development and design of artificial intelligence-related research. The ultimate goal is to allow patients to receive better quality personalized treatment, which will lead to a better prognosis.

JTD Annual Report 2022

We are glad to present the 2022 Annual Report of JTD here. Celebrating its new increased impact factor of 3.005, JTD continues to publish cutting-edge research covering the whole spectrum of thoracic disease.

Extracorporeal Life Support in Thoracic Surgery (Ongoing)

This special series on “Extracorporeal Life Support in Thoracic Surgery” is edited by Dr. Ilhan Inci from Klinik Hirslanden Zurich, Switzerland

Twelfth London International Cough Symposium (12^th LICS)

The Twelfth London International Cough Symposium will take place on 13/14 July 2022 in London. It will gather clinicians and scientists for a review of the latest clinical and research advances, evolving ideas and new treatments regarding acute and chronic cough. There will be a review of the diseases associated with acute and chronic cough, underlying pathophysiological mechanisms, and cutting-edge treatments for hypersensitive cough.

A Guide for Managing Patients with Stage I NSCLC: Deciding between Lobectomy, Segmentectomy, Wedge, SBRT and Ablation

This series on “A Guide for Managing Patients with Stage I NSCLC: Deciding between Lobectomy, Segmentectomy, Wedge, SBRT and Ablation” is edited by Dr. Frank C. Detterbeck, from Yale University School of Medicine, New Haven, CT, USA

Minimally Invasive Treatment of Pectus Deformities (Ongoing)

The series on “Minimally Invasive Treatment of Pectus Deformities” is edited by Prof. Erik R. de Loos from Zuyderland medical center (the Netherlands), Prof. Frank-Martin Haecker from University of Basel (Switzerland) and Prof. Jean H.T. Daemen from Zuyderland medical center (the Netherlands).

Interviews with Outstanding Authors (2022)

In 2022, many authors bring new findings, practical information on the diagnosis and treatment of conditions related to thoracic disease to our journal. Their articles published with us have received very well feedback in the field and stimulate a lot of discussions and new insights among the peers.

Hereby, we would like to highlight some of our outstanding authors who have been making immense efforts in their research fields, with a brief interview of their unique perspectives and insightful views as authors.

Why is the outcome good? Secrets of lung transplantation in Japan (Ongoing)

The series on “Why is the outcome good? Secrets of lung transplantation in Japan” is edited by Prof. Masaaki Sato from the University of Tokyo (Japan).

6th Clinical Update Sleep™: International Conference

Guy’s and St Thomas’ 6th Clinical Update Sleep™: International Conference will guide you through the latest developments of sleep medicine, and will review the evidence for the diagnosis and treatment of patients with sleep disorders, including obstructive sleep apnoea, hypersomnia, parasomnia and insomnia, as well as circadian rhythm disorders.

Chest Wall Resections and Reconstructions (Ongoing)

The series on “Chest Wall Resections and Reconstructions” is edited by Prof. Erik de Loos from the Zuyderland Medical Center (The Netherlands), José Ribas de Campos from the Hospital Israelita Albert Einstein (Brazil), Jean Daemen from the Zuyderland Medical Center (The Netherlands).

European Perspectives in Thoracic Surgery (2020) - the Seven Edition

For the 7^th consecutive year the Editorial Board of the Journal of Thoracic Disease (JTD) presents a series collecting invited lectures presented during the European Society of Thoracic Surgeons (ESTS) Annual Conference. During the past 2 years, the Covid-19 pandemic hugely impacted on the organization of all medical conferences and educational programs including the ESTS Annual Meeting. It is our hope that we will soon get back to a new normality, where people can reconvene in person at the ESTS Annual Conference, sharing experiences, physically interacting at the Conferences and at the associated social events.

Interventional Pulmonology in the Intensive Care Unit

Bronchoscopy and airway procedures represent a large portion of the interventional pulmonology that occurs in the ICU. The complementary roles of intensivists and interventional pulmonologists are highlighted in articles that delineate nuances of bronchoscopy in critically ill patients both intubated and non-intubated, novel methods to manage life threatening hemoptysis and foreign body aspiration, utilization of rigid bronchoscopy to alleviate respiratory failure from central airway obstruction, challenges and pitfalls of performing bronchoscopy on patients receiving extracorporeal life support and the evolving role of endobronchial ultrasound in the ICU.

Robotic Thoracic Surgery

Conventional thoracic incisions are associated with significant pain and morbidity. Historically thoracic procedures required prolong hospital stay and recovery time. Minimally invasive approaches, initially video assisted thoracic surgery (VATS) and recently the robotic approach, have offset these morbidities without compromising the technical and oncological principles of thoracic surgery. In this series, world leaders in robotic thoracic surgery have provided an update on these common thoracic procedures to elucidate the indications and techniques for the readers.

Radiotherapy for Brain Metastases from Lung Cancer

All aforementioned considerations relate to the patients with preserved performance status who may benefit from the progress in the management of lung cancer. However, among patients with brain metastases from lung cancer, there is a significant proportion of patients with poor performance status, for whom WBRT has no benefit over the use of steroids alone. These patients should benefit from the early introduction of all measures of palliative care without radiotherapy, because such an approach improves the quality of life, especially in patients with lung cancer.

Thoracic Surgery Worldwide (Ongoing)

Starting in 2021, the Journal of Thoracic Disease (JTD) will be launching a new regular feature in each issue entitled “Thoracic Surgery Worldwide”. The aim of this series is to showcase the status of Thoracic Surgery around the world. This Series is edited by Dr Alan Sihoe from Gleneagles Hong Kong Hospital, HK.

Modified SEIR and AI prediction of the epidemics trend of COVID-19 in China under public health interventions

Background: The coronavirus disease 2019 (COVID-19) outbreak originating in Wuhan, Hubei province, China, coincided with chunyun, the period of mass migration for the annual Spring Festival. To contain its spread, China adopted unprecedented nationwide interventions on January 23, 2020. These policies included large-scale quarantine, strict controls on travel and extensive monitoring of suspected cases. However, it is unknown whether these policies have had an impact on the epidemic. We sought to show how these control measures impacted the containment of the epidemic.

Testimonials for JTD from Eminent Experts Worldwide

Eminent Experts Worldwide, including editorial board members, authors, and readers, who know the journal well, provided testimonials for JTD. We are thankful for their support for the journal.

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Vol 15, No 2 (February, 2023)

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JTD Chinese Edition more

中国香港胸外科现状简介

中国香港的胸外科早在20世纪50年代还是一个新兴的亚专科，主要关注于非... More >>

中国台湾医疗系统与胸外科发展

中国台湾位于南海以北，距大陆东南沿海约180公里，总面积3.6万平方公里... More >>

从赫尔辛基大学医院的视角介绍芬兰胸外科的历史、现状与未来

由于肿瘤治疗的进步，胸外科领域得到快速发展，如免疫肿瘤学、新方法... More >>

Air Pollution more

Age modification of ozone associations with cardiovascular disease risk in adults: a potential role for soluble P-selectin and blood pressure

Drew B. Day, Merlise A. Clyde, Jianbang Xiang, Feng Li, Xiaoxing Cui, Jinhan Mo, Jicheng Gong,... More >>

Assessment of a respiratory face mask for capturing air pollutants and pathogens including human influenza and rhinoviruses

S. Steve Zhou, Salimatu Lukula, Cory Chiossone, Raymond W. Nims, Donna B. Suchmann, M. Khalid Ijaz More >>

Relationship between free and total malondialdehyde, a well-established marker of oxidative stress, in various types of human biospecimens

Xiaoxing Cui, Jicheng Gong, Hailong Han, Linchen He, Yanbo Teng, Teresa Tetley, Rudy Sinharay,... More >>

GARD Section more

The nationwide program of allergic disease prevention as an implementation of GARD guidelines in Poland

Filip Raciborski, Bolesław Samoliński, Edyta Krzych-Fałta, Aleksandra Grąbczewska, Filip... More >>

A strategy for measuring health outcomes and evaluating impacts of interventions on asthma and COPD—common chronic respiratory diseases in Global Alliance against Chronic Respiratory Diseases (GARD) countries

Teresa To, Alvaro A. Cruz, Giovanni Viegi, Rachel McGihon, Nikolai Khaltaev, Arzu Yorgancioglu,... More >>

Integrating primary care of chronic respiratory disease, cardiovascular disease and diabetes in Brazil: Practical Approach to Care Kit (PACK Brazil): study protocol for randomised controlled trials

Max O. Bachmann, Eric D. Bateman, Rafael Stelmach, Álvaro A. Cruz, Matheus Pacheco de Andrade,... More >>

Cough Section more

Clinical Practice Guidelines for Diagnosis and Management of Cough—Chinese Thoracic Society (CTS) Asthma Consortium

Kefang Lai, Huahao Shen, Xin Zhou, Zhongmin Qiu, Shaoxi Cai, Kewu Huang, Qiuping Wang, Changzheng... More >>

Methodology for development of the Chinese evidence-based Clinical Practice Guideline of the Diagnosis and Management of Cough

Mei Jiang, Yan-Qing Xie, Jia-Xing Xie, Xiang-Wei Zou, Ke-Fang Lai More >>

Cough frequency monitors: can they discriminate patient from environmental coughs?

Stefan T. Kulnik, Natalie M. Williams, Lalit Kalra, John Moxham, Surinder S. Birring More >>

Endorsement

Journal of Thoracic Disease is endorsed by International COPD Coalition.

The China Asthma Alliance

The Brazilian Society of Thoracic Surgery (SBCT)

The Italian Society of Thoracic Surgery (SICT)

The Italian VATS Group:

Global Alliance against Chronic Respiratory Diseases (GARD)

Editorial

Thoracic drain management using a digital system

Takeo Nakada, Takashi Ohtsuka

PDF Pages: 219-222 Full Text (193) COI Form Open Access

Does the maze procedure predispose to acute kidney injury?

Alicia X. F. Chia, Philip Y. K. Pang

PDF Pages: 223-225 Full Text (182) COI Form Open Access

Incidence of bronchopleural fistula after pneumonectomy in an era of revolution

Puja Gaur Khaitan

PDF Pages: 226-228 Full Text (118) COI Form Open Access

The final frontier of subdiaphragmatic abscess management: should we bury the scalpel?

Carlos Augusto Metidieri Menegozzo, Marcos Roberto de Menezes, Edivaldo Massazo Utiyama

PDF Pages: 229-231 Full Text (105) COI Form Open Access

Adopting the robotic platform for anatomic lung resections: real life lessons for the tech enthusiast

Charles Bakhos, Roman Petrov, Abbas Abbas

PDF Pages: 232-234 Full Text (106) COI Form Open Access

A stitch in time: age impacts survival in repair of atrioventricular septal defects

Damien M. Wu, Igor E. Konstantinov, Christian P. Brizard, Edward Buratto

PDF Pages: 235-237 Full Text (194) COI Form Open Access

The pros and cons of uniportal VATS segmentectomy in the treatment of early-stage lung cancer: should the procedure be prioritized?

Masaaki Sato

PDF Pages: 238-241 Full Text (104) COI Form Open Access

Thoracoscopic anatomical segmentectomy for early-stage non-small cell lung cancer: minimally invasive surgery involving various approaches

Hirohisa Kato

PDF Pages: 242-245 Full Text (116) COI Form Open Access

Beyond the limits: journey to feasible and safe uniportal VATS surgery for lung cancer

Mi Hyoung Moon

PDF Pages: 246-249 Full Text (92) COI Form Open Access

Is a single port enough for the learned thoracic surgeons?

Yojiro Yutaka, Hiroshi Date

PDF Pages: 250-252 Full Text (112) COI Form Open Access

Can major lung resection under local anesthesia become widespread?

Takashi Suda

PDF Pages: 253-255 Full Text (105) COI Form Open Access

Opioid-sparing opportunities in the thoracic surgery pathway

Genevieve F. Gilson, Sandeep J. Khandhar

PDF Pages: 256-259 Full Text (90) COI Form Open Access

Original Article

Clinical outcomes of immune checkpoint inhibitor therapy for advanced lung adenosquamous carcinoma

Jingwen Wei, Jing Xiang, Yue Hao, Jinfei Si, Xiaodong Gu, Manyi Xu, Zhengbo Song

PDF Pages: 260-269 Full Text (198) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Anatomic lung resection after immune checkpoint inhibitors for initially unresectable advanced-staged non-small cell lung cancer: a retrospective cohort analysis

Harry Etienne, Ludovic Fournel, Pierre Mordant, Bertrand Richard Delatour, Karel Pfeuty, Gil Frey, Agathe Seguin-Givelet, Alex Fourdrain, Christophe Lancelin, Pascal Berna, Antoine Legras, Marco Alifano, Patrick Bagan, Jalal Assouad

PDF Pages: 270-280 Full Text (351) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

First insights into the role of wall shear stress in the development of a distal stent graft induced new entry through computational fluid dynamics simulations

Anja Osswald, Alexander Weymann, Konstantinos Tsagakis, Alina Zubarevich, Matthias Thielmann, Bastian Schmack, Arjang Ruhparwar, Christof Karmonik

PDF Pages: 281-290 Full Text (147) Reporting Checklist Data Sharing Statement COI Form Open Access

Ex-vivo exploration of an endobronchial sentinel lymph node procedure in lung cancer for optimizing workflow and evaluating feasibility of novel imaging tools

Desi K. M. ter Woerds, Roel L. J. Verhoeven, Stefan M. van der Heide, Ad F. T. M. Verhagen, Erik H. J. G. Aarntzen, Erik H. F. M. van der Heijden

PDF Pages: 291-299 Full Text (229) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Interleukin-11 in idiopathic pulmonary fibrosis: predictive value of prognosis and acute exacerbation

Toru Arai, Masaki Hirose, Tomoko Kagawa, Kazuyoshi Hatsuda, Yoshikazu Inoue

PDF Pages: 300-310 Full Text (153) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Inflammatory myositis-associated interstitial lung disease can be distinguished from that associated with other connective tissue diseases

Hanna M. Nurmi, Pia K. Elfving, Hannu-Pekka Kettunen, Sanna-Katja Suoranta, Henrik M. I. Järvinen, Vili A. E. Kuittinen, Minna K. Purokivi, Riitta L. Kaarteenaho, Heikki O. Koskela

PDF Pages: 311-322 Full Text (144) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

When to proceed to surgical rib fixation?—A single-institution clinical experience

Yaniss Belaroussi, Gabrielle Drevet, Valentin Soldea, Arnaud Patoir, Renaud Grima, Albrice Levrat, Pascal Rosamel, François Tronc, Jean-Stephane David, Jean-Michel Maury

PDF Pages: 323-334 Full Text (129) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Uniportal vs. multiportal thoracoscopic segmentectomy: a north American study

Ilitch Diaz-Gutierrez, Charles Antoine Menier, Félix H. Savoie-White, Jesse E. Doyle, Qi Wang, Rafael S. Andrade, Paula Ugalde Figueroa

PDF Pages: 335-347 Full Text (141) Reporting Checklist Data Sharing Statement COI Form Open Access

Global trends in the burden of esophageal cancer, 1990−2019: results from the Global Burden of Disease Study 2019

Yu Jiang, Yuechun Lin, Yaokai Wen, Wenhai Fu, Rui Wang, Jiaxi He, Jianrong Zhang, Zhufeng Wang, Fan Ge, Zhenyu Huo, Runchen Wang, Haoxin Peng, Xiangrong Wu, Jianxing He, Shuben Li

PDF Pages: 348-364 Full Text (156) Reporting Checklist Peer Review File COI Form Open Access

Laboratory blood test profiling reveals distinct biochemical and hemocyte features of KRAS mutated non-small cell lung cancer

Limin Ou, Xiuyu Cai, Wenchuang Zeng, Liyan Huang, Qiuhua Deng, Hailing Tang, Zhuxing Chen, Huan Zhou, Yongping Lin, Liping Liu, Wenhua Liang

PDF Pages: 365-375 Full Text (143) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Risk factors for postoperative cerebral infarction in patients after lung resection: a single-center case-control study

Shenhu Gao, Yuwei Zhou, Rong Yang, Chengli Du, Yihe Wu

PDF Pages: 376-385 Full Text (112) Reporting Checklist Data Sharing Statement COI Form Open Access

Immunocyte count combined with CT features for distinguishing pulmonary tuberculoma from malignancy among non-calcified solitary pulmonary solid nodules

Zihao Liu, Haoyu Ran, Xiran Yu, Qingchen Wu, Cheng Zhang

PDF Pages: 386-398 Full Text (107) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Recipient, donor, and surgical factors leading to primary graft dysfunction after lung transplant

Takahide Toyoda, Emily Jeong Cerier, Adwaiy Jayant Manerikar, Viswajit Kandula, Ankit Bharat, Chitaru Kurihara

PDF Pages: 399-409 Full Text (110) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Tracheostomy insertion in COVID-19: insertion practice and factors leading to unplanned tube exchange

Peter McCauley, Amr Mohammed, Michelle Casey, Eslam Ramadan, Sinéad Galvin, James Paul O’Neill, Gerard Curley, Imran Sulaiman, Michael Emmet O’Brien, James O’Rourke

PDF Pages: 410-422 Full Text (135) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Contemporary real-world radiotherapy outcomes of unresected locally advanced non-small cell lung cancer

Mohammad Gouran-Savadkoohi, Aruz Mesci, Gregory R. Pond, Anand Swaminath, Kimmen Quan, Jim Wright, Theodoros Tsakiridis

PDF Pages: 423-433 Full Text (135) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Incidence and diagnostic validity of difficult airway in emergency departments in China: a cross-sectional survey

Yili Dai, Joseph Harold Walline, Yao Wu, Huadong Zhu, Jun Xu, Xuezhong Yu

PDF Pages: 434-441 Full Text (112) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Comparison of lymph node metastasis pattern from esophagogastric junction adenocarcinoma versus very low thoracic esophageal squamous cancer: a propensity-matched analysis

Zhao Ma, Chuangui Chen, Xiaobin Shang, Jie Yue, Hongjing Jiang

PDF Pages: 442-451 Full Text (108) Reporting Checklist Data Sharing Statement COI Form Open Access

Real-world experience of arbidol for Omicron variant of SARS-CoV-2

Jingya Zhao, Yong Li, Rong Chen, Yanping Xu, Qingyuan Yang, Haiqing Zhang, Zhengxin Yin, Weiting Gu, Jinsong Hu, Li Chen, Jian Li, Guang Ning, Qijian Cheng, Min Zhou, Jieming Qu

PDF Pages: 452-461 Full Text (143) Reporting Checklist Data Sharing Statement COI Form Open Access

Clinical features of recurrent spontaneous pneumomediastinum

Hirotaka Kumeda, Gaku Saito, Takashi Eguchi, Daisuke Hara, Kimihiro Shimizu

PDF Pages: 462-471 Full Text (116) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Impaired exercise capacity in individuals with non-obstructive small airway dysfunction

Zhishan Deng, Xiaochen Li, Chenglong Li, Youlan Zheng, Fan Wu, Zihui Wang, Sha Liu, Heshen Tian, Jinzhen Zheng, Jieqi Peng, Peiyu Huang, Huajing Yang, Shan Xiao, Xiang Wen, Changli Yang, Xiangwen Luo, Gongyong Peng, Bing Li, Yumin Zhou, Pixin Ran

PDF Pages: 472-483 Full Text (136) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Initial Asian experience of the branched E-vita open NEO in complex aortic pathologies

Jacky Y. K. Ho, Chong Hoon Kim, Simon C. Y. Chow, Micky W. T. Kwok, Ha Lee, Tae-Hoon Kim, Takuya Fujikawa, Randolph H. L. Wong, Suk-Won Song

PDF Pages: 484-493 Full Text (131) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Dyspnea in patients with stage IV non-small cell lung cancer: a population-based analysis of disease burden and patterns of care

Michael Yan, Michael Tjong, Wing C. Chan, Gail Darling, Victoria Delibasic, Laura E. Davis, Mark Doherty, Julie Hallet, Biniam Kidane, Alyson Mahar, Nicole Mittmann, Ambica Parmar, Vivian Tan, Hendrick Tan, Frances C. Wright, Natalie G. Coburn, Alexander V. Louie

PDF Pages: 494-506 Full Text (155) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Lessons learned by thoracic surgeons during the COVID-19 pandemic

Helen J. Madsen, Anne Lambert-Kerzner, Ellison Mucharsky, Joseph D. Phillips, Elizabeth A. David, David D. Odell, Adam R. Dyas, Robert A. Meguid

PDF Pages: 507-515 Full Text (129) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Honeycomb lung is a major risk factor for preoperative radiological tumor size underestimation in patients with primary lung cancer

Hisato Ishizawa, Yasushi Matsuda, Yoshiharu Ohno, Eiko Sakurai, Atsuhiko Ota, Hidekazu Hattori, Tetsuya Tsukamoto, Masaaki Matsunaga, Hiroshi Kawai, Yamato Suzuki, Hiromitsu Nagano, Takahiro Negi, Daisuke Tochii, Sachiko Tochii, Takashi Suda, Yasushi Hoshikawa

PDF Pages: 516-528 Full Text (159) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

MicroRNA-186-5p inhibits H9c2 cells apoptosis induced by oxygen-glucose deprivation by targeting ERK1/2

Wennan Nie, Jia Wu, Xiaoyang Yu, Zhuolin Li, Xiaomin Cai, Wenyan Wei, Cheng Wang, Junjun Wang

PDF Pages: 529-541 Full Text (136) Reporting Checklist Data Sharing Statement COI Form Open Access

Real-world evidence of safety and influence for lung cancer surgery under COVID-19 pandemic in Japan

Taketo Kato, Ryotaro Katsuya, Shoji Okado, Keiyu Sato, Osamu Noritake, Keita Nakanishi, Misa Noguchi, Yuka Kadomatsu, Harushi Ueno, Naoki Ozeki, Shota Nakamura, Koichi Fukumoto, Toyofumi Fengshi Chen-Yoshikawa

PDF Pages: 542-551 Full Text (102) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Removing different number of regional lymph nodes affects survival outcomes of operable patients at stage IIA non-small cell lung cancer (according to the 8th edition staging)

Xuan Li, Guoshu Li, Yukun Wang, Min Tan, Changhui Wang

PDF Pages: 552-567 Full Text (149) Reporting Checklist COI Form Open Access

Standardization of intra- and peri-operative management to reduce postoperative drainage time after major thoracoscopic pulmonary resections

Hitoshi Igai, Kazuki Numajiri, Fumi Ohsawa, Mitsuhiro Kamiyoshihara

PDF Pages: 568-578 Full Text (103) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Cone-beam computed tomography-guided endobronchial ultrasound using an ultrathin bronchoscope for diagnosis of peripheral pulmonary lesions: a prospective pilot study

Naoya Kawakita, Hiroaki Toba, Shinichi Sakamoto, Naoki Miyamoto, Mika Takashima, Yukikiyo Kawakami, Kazuya Kondo, Hiromitsu Takizawa

PDF Pages: 579-588 Full Text (143) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Polymorphisms in the FCER2 gene have associations with asthma and chronic obstructive pulmonary disease

Zhoude Zheng, Jia Li, Yi Liu, Lun Li, Tingting Huang, Yilin Huang, Siyao Song, Jinming Gao

PDF Pages: 589-599 Full Text (147) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

The relationship between tumor infiltrating immune cells and the prognosis of patients with lung adenocarcinoma

Zhuang Tong, Xu Wang, Hongyu Liu, Jian Ding, Yinling Chu, Xin Zhou

PDF Pages: 600-610 Full Text (191) Reporting Checklist Data Sharing Statement COI Form Open Access

Relationship between valvular structure and biochemical indices of non-valvular atrial fibrillation and senile degenerative valvular heart disease

Jian-Qin Chen, Xin Zeng, Kun-Con Li, Jing-Long Huang, Bing-Li Guo, Xuan Zhou

PDF Pages: 611-619 Full Text (163) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Risk factor analysis of postoperative cerebral infarction in thoracic surgery patients by propensity-score matching-a single institution retrospective cohort study

Qirui Chen, Ying Ji, Jing Wang, Yan Zhao, Xin Ye, Yi Liu

PDF Pages: 620-626 Full Text (149) Reporting Checklist Data Sharing Statement COI Form Open Access

The value of serum Sema4D level in reflecting the inflammatory state of acute ST-segment elevation myocardial infarction

Koulong Zheng, Jie Bai, Louyuan Xu, Liang Chen

PDF Pages: 627-634 Full Text (126) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Value of contrast-enhanced magnetic resonance imaging-T2WI-based radiomic features in distinguishing lung adenocarcinoma from lung squamous cell carcinoma with solid components >8 mm

Maoyuan Yang, Liang Shi, Tianwei Huang, Guangzheng Li, Hancheng Shao, Yijun Shen, Jun Zhu, Bin Ni

PDF Pages: 635-648 Full Text (176) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Serum vitamin D₃ deficiency can affect the efficacy of sublingual immunotherapy in children with allergic rhinitis: a retrospective cohort study

Liang Li, Xiaojian Cui, Xinjie Zhang, Lisheng Zheng, Xuyuan Sun, Cuihong Yang, Jianbo Shu, Guangping Liu

PDF Pages: 649-657 Full Text (248) Reporting Checklist Data Sharing Statement COI Form Open Access

The association of coagulation indicators with in-hospital acute kidney injury and malignant events of patients with acute aortic dissection: a retrospective cohort study

Shiyan Jiang, Yinhua Li, Chenlin Li, Zhouwu Shu, Shiwan Wu, Xiaojia Lu, Yue Liu, Yinlong Deng, Yequn Chen, Peiwei Cai, Bin Wang

PDF Pages: 658-667 Full Text (146) Reporting Checklist Data Sharing Statement COI Form Open Access

Systematic review and meta-analysis of the risk factors for postoperative delirium in patients with acute type A aortic dissection

Shijian Wang, Tianguang Wang, Chaoyang Zhao, Dewen Lin

PDF Pages: 668-678 Full Text (154) Reporting Checklist COI Form Open Access

Differentiating between pulmonary adenocarcinoma and squamous cell carcinoma by spectral CT volumetric quantitative analysis: a comparative study with conventional spectral analysis

Li-Juan Zhong, Na Yu, Xin-Jie Zhou, Lang-Zhou Fu, Dai-Quan Zhou, Yi Wang, Min Yan

PDF Pages: 679-689 Full Text (125) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Immune-related thyroid dysfunction is associated with improved long-term prognosis in patients with non-small cell lung cancer treated with immunotherapy: a systematic review and meta-analysis

Zhengjun Li, Ying Xia, Mozhu Xia, Chang Liu, Tao Wang, Yongyu Liu, Yi Ren

PDF Pages: 690-700 Full Text (177) Reporting Checklist COI Form Open Access

Postoperative delirium and its influencing factors in elderly patients with lung cancer in the intensive care unit

Yanna Lu, Xiaoxin Liu

PDF Pages: 701-710 Full Text (190) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Short Communication

Is SARS-COV-2 associated with alpha-1 antitrypsin deficiency?

Carlota Rodríguez-García, Emilio Rodríguez-Ruiz, Alberto Ruano-Raviña, Raquel Cruz, María Piñeiro-Lamas, Ana Casal, Pablo Lapunzina, Ángel Carracedo, Luis Valdés; on behalf of Scourge Consortium

PDF Pages: 711-717 Full Text (127) COI Form Open Access

Study Protocol

Neoadjuvant therapy with immunoagent (nivolumab) or placebo plus chemotherapy followed by surgery and adjuvant treatment in subjects with resectable esophageal squamous cell carcinoma: study protocol of a randomized, multicenter, double blind, phase II trial (NATION-2203 trial)

Jun Yin, Siyun Lin, Yong Fang, Heng Jiao, Zongwei Chen, Han Tang, Jianmin Gu, Shaoyuan Zhang, Linyi Sun, Yin Li, Yongtao Han, Qixun Chen, Haiquan Chen, Zhigang Li, Lijie Tan

PDF Pages: 718-730 Full Text (159) Reporting Checklist COI Form Open Access

Review Article

Lung cancer with air lucency: a systematic review and clinical management guide

Frank C. Detterbeck, Ulas Kumbasar, Andrew X. Li, Ami N. Rubinowitz, Leah Traube, Babina Gosangi, Brooks V. Udelsman, Brett C. Bade, Sora Ely, Gaspar Barreto, Lynn T. Tanoue, Edith M. Marom, M. Patricia Rivera

PDF Pages: 731-746 Full Text (158) Reporting Checklist COI Form Open Access

The beginning of a new era in induction treatment for operable non-small cell lung cancer: a narrative review

Shuichi Shinohara, Yusuke Takahashi, Katsuhiro Masago, Hirokazu Matsushita, Hiroaki Kuroda

PDF Pages: 747-758 Full Text (222) Reporting Checklist Peer Review File COI Form Open Access

Esophageal diverticula: from diagnosis to therapeutic management—narrative review

Adrian Constantin, Silviu Constantinoiu, Florin Achim, Bogdan Socea, Daniel Ovidiu Costea, Dragos Predescu

PDF Pages: 759-779 Full Text (150) Reporting Checklist COI Form Open Access

Intrathoracic vacuum therapy for the therapy of pleural empyema—a systematic review and analysis of the literature

Björn-Ole Stüben, Gabriel A. Plitzko, Matthias Reeh, Nathaniel Melling, Jakob R. Izbicki, Kai Bachmann, Michael Tachezy

PDF Pages: 780-790 Full Text (111) Reporting Checklist Peer Review File COI Form Open Access

Suggested robotic-assisted thoracic surgery training curriculum

Muteb Al Zaidi, Gavin M. Wright, Kazuhiro Yasufuku

PDF Pages: 791-798 Full Text (119) COI Form Open Access

Editorial on Clinical Update Sleep 2023¹

Clinical Update Sleep: Life Eessentials and NHS England ‘Optimal Sleep Pathway’

Joerg Steier, Alanna Hare, Abdulaziz Alsharifi; on behalf of the Organising Team for the Clinical Update Sleep

PDF Pages: 799-801 Full Text (90) COI Form Open Access

Original Article on Clinical Update Sleep 2023¹

Peri-operative outcomes of bariatric surgery in obstructive sleep apnoea: a single-centre cohort study

Cristiano van Zeller, Richard Brown, Michael Cheng, Johan Meurling, Barbara McGowan, Joerg Steier

PDF Pages: 802-811 Full Text (Video) (318) Reporting Checklist Data Sharing Statement COI Form Open Access

Cardioprotective medication in Duchenne muscular dystrophy: a single-centre cohort study

Janneta Kisel, Emily Ballard, Eui-Sik Suh, Nicholas Hart, Stam Kapetanakis, Shelley Srivastava, Philip Marino, Patrick Murphy, Joerg Steier

PDF Pages: 812-819 Full Text (143) Reporting Checklist Data Sharing Statement COI Form Open Access

The effect of a change from face-to-face to remote positive airway pressure education for patients with sleep apnoea during the coronavirus disease-2019 pandemic: a prospective cohort study

Imran Johan Meurling, Adam Birdseye, Rohan Gell, Eliza Sany, Richard Brown, Sean Higgins, Rexford Muza, David O’Regan, Guy Leschziner, Joerg Steier, Ivana Rosenzweig, Panagis Drakatos

PDF Pages: 820-828 Full Text (238) Reporting Checklist Data Sharing Statement COI Form Open Access

Brief Report on Clinical Update Sleep 2023¹

Nocturnal continuous positive airway pressure offers symptomatic benefit in excessive dynamic airway collapse despite normal sleep study

Louise Olley, Joerg Steier, Georgios Kaltsakas

PDF Pages: 829-834 Full Text (123) COI Form Open Access

Editorial on Prolonged Air Leak after Lung Surgery: Prediction, Prevention and Management²

Prolonged air leak after lung surgery: prediction, prevention and management

Francesco Zaraca, Roberto Crisci, Florian Augustin, Alessandro Brunelli, Luca Bertolaccini

PDF Pages: 835-838 Full Text (113) COI Form Open Access

A brief appraisal on the GRADE methodology and the development of recommendations on the management of prolonged air leaks by the PALAS Study Group

Francesco Zaraca, Luca Bertolaccini; PALAS Study Group

PDF Pages: 839-844 Full Text (94) COI Form Open Access

Editorial Commentary on Prolonged Air Leak after Lung Surgery: Prediction, Prevention and Management²

Should we use a biophysical approach in the classification and management of air leakage after lung resection?

Luca Bertolaccini, Andrea Cara, Claudia Bardoni, Lorenzo Spaggiari, Francesco Zaraca

PDF Pages: 845-848 Full Text (106) COI Form Open Access

Original Article on Prolonged Air Leak after Lung Surgery: Prediction, Prevention and Management²

Prolonged air leak after video-assisted thoracic anatomical pulmonary resections: a clinical predicting model based on data from the Italian VATS group registry, a machine learning approach

Duilio Divisi, Marco Pipitone, Reinhold Perkmann, Luca Bertolaccini, Carlo Curcio, Francesco Baldinelli, Roberto Crisci, Francesco Zaraca; Italian VATS group

PDF Pages: 849-857 Full Text (143) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Prolonged air leak after segmentectomy: incidence and risk factors

Michael R. Gooseman, Alessandro Brunelli, Nilanjan Chaudhuri, Richard Milton, Peter Tcherveniakov, Kostas Papagiannopoulos, Laura Valuckiene

PDF Pages: 858-865 Full Text (126) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Risk factors, complications and costs of prolonged air leak after video-assisted thoracoscopic surgery for primary lung cancer

Florian Ponholzer, Caecilia Ng, Herbert Maier, Paolo Lucciarini, Dietmar Öfner, Florian Augustin

PDF Pages: 866-877 Full Text (141) Reporting Checklist Data Sharing Statement COI Form Open Access

Review Article on Prolonged Air Leak after Lung Surgery: Prediction, Prevention and Management²

Intraoperative prevention and conservative management of postoperative prolonged air leak after lung resection: a systematic review

Vittorio Aprile, Diana Bacchin, Fabrizia Calabrò, Stylianos Korasidis, Maria Giovanna Mastromarino, Marcello Carlo Ambrogi, Marco Lucchi

PDF Pages: 878-892 Full Text (178) Reporting Checklist Peer Review File COI Form Open Access

The role of new staplers in reducing the incidence of air leak

Alessandro Marra, Aleksandar Yankulov

PDF Pages: 893-900 Full Text (211) Peer Review File COI Form Open Access

Enhanced recovery after surgery and chest tube management

Tim J. P. Batchelor

PDF Pages: 901-908 Full Text (314) Peer Review File COI Form Open Access

Prolonged air leak after robotic lung resection: a narrative review

Piergiorgio Muriana, Francesca Rossetti, Stefano Viscardi, Pierluigi Novellis, Giulia Veronesi

PDF Pages: 909-917 Full Text (166) Reporting Checklist Peer Review File COI Form Open Access

Original Article of Sleep Section³

Effect of switching from continuous to bilevel positive airway pressure on sleep quality in patients with obstructive sleep apnea: the prospective POP IN VAuto study

Alain Palot, Xuân-Lan Nguyên, Sandrine Launois, Arnaud Prigent, Andrea Graml, Elodie Aversenq, Christian Koltes, Didier Recart, Florent Lavergne

PDF Pages: 918-927 Full Text (263) Reporting Checklist Data Sharing Statement COI Form Open Access

Original Article of Cough Section

Diagnostic yield of chest radiograph in management of adults with difficult-to-treat chronic cough—retrospective study

Olga Truba, Marta Dabrowska, Elzbieta M. Grabczak, Katarzyna Bialek-Gosk, Aleksandra Rybka-Fraczek, Karolina Klimowicz, Malgorzata Zukowska, Rafal Krenke

PDF Pages: 928-939 Full Text (104) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Letter to the Editor

Medical thoracoscopy: effective, cheap and safe for empyema

Vinod Govindasaami

PDF Pages: 940-941 Full Text (87) COI Form Open Access

Erratum

Erratum to the effects of hydrogen treatment in a cigarette smoke solution-induced chronic obstructive pulmonary disease-like changes in an animal model

Editorial Office

PDF Pages: 942 Full Text (80) Open Access

Disclosure

1. The series “Clinical Update Sleep 2023” was commissioned by the editorial office, Journal of Thoracic Disease without any funding or sponsorship. Joerg Steier served as the unpaid Guest Editor for the series.

2. The series “Prolonged air leak after lung surgery: prediction, prevention and management” was commissioned by the editorial office, Journal of Thoracic Disease and sponsored by Bard Limited. Bard Limited has no interference on the contents of the special series. Roberto Crisci, Alessandro Brunelli, Florian Augustin and Francesco Zaraca served as the unpaid Guest Editors for the series.

3. The series “Sleep Section” was commissioned by the editorial office, Journal of Thoracic Disease without any funding or sponsorship.

Original Article

Nonintubated thoracoscopic lung resection: a 3-year experience with 285 cases in a single institution

Ke-Cheng Chen, Ya-Jung Cheng, Ming-Hui Hung, Yu-Ding Tseng, Jin-Shing Chen

Delays in the diagnosis of lung cancer

Peter M Ellis, Rachel Vandermeer

The diagnostic utility of endobronchial ultrasonography with a guide sheath and tomosynthesis images for ground glass opacity pulmonary lesions

Takehiro Izumo, Shinji Sasada, Christine Chavez, Takaaki Tsuchida

Hydration with magnesium and mannitol without furosemide prevents the nephrotoxicity induced by cisplatin and pemetrexed in patients with advanced non-small cell lung cancer

Keiko Muraki, Ryo Koyama, Yuichiro Honma, Shigehiro Yagishita, Takehito Shukuya, Rina Ohashi, Fumiyuki Takahashi, Kenji Kido, Shin-ichiro Iwakami, Shinichi Sasaki, Akihiko Iwase, Kazuhisa Takahashi

Local control rates with five-fraction stereotactic body radiotherapy for oligometastatic cancer to the lung

Deepinder Singh, Yuhchyau Chen, Mary Z. Hare, Kenneth Y. Usuki, Hong Zhang, Thomas Lundquist, Neil Joyce, Michael C. Schell, Michael T. Milano

Theoretical models of carcinogenic particle deposition and clearance in children’s lungs

Robert Sturm

A novel paradigm in the treatment of oligometastatic non-small cell lung cancer

Salma K Jabbour, Parima Daroui, Dirk Moore, Edward Licitra, Molly Gabel, Joseph Aisner

Radiotherapy for a second primary lung cancer arising post-pneumonectomy: planning considerations and clinical outcomes

Sashendra Senthi, Cornelis J. A. Haasbeek, Frank J. Lagerwaard, Wilko F. Verbakel, Patricia F. de Haan, Ben J. Slotman, Suresh Senan

Impact of metformin use on survival in locally-advanced, inoperable non-small cell lung cancer treated with definitive chemoradiation

Inaya Ahmed, Adam Ferro, Alan Cohler, John Langenfeld, Sujani G. Surakanti, Joseph Aisner, Wei Zou, Bruce G. Haffty, Salma K. Jabbour

Utility of EBUS-TBNA for diagnosis of mediastinal tuberculous lymphadenitis: a multicentre Australian experience

James Geake, Gary Hammerschlag, Phan Nguyen, Peter Wallbridge, Grant A. Jenkin, Tony M. Korman, Barton Jennings, Douglas F. Johnson, Louis B. Irving, Michael Farmer, Daniel P. Steinfort

Comparative outcomes of squamous and non-squamous non-small cell lung cancer (NSCLC) patients in phase II studies of ASA404 (DMXAA) – retrospective analysis of pooled data

Mark J McKeage, Michael B Jameson, AS1404-201 Study Group Investigators

High prevalence of gene abnormalities in young patients with lung cancer

Osamu Nagashima, Rina Ohashi, Yasuko Yoshioka, Ai Inagaki, Manabu Tajima, Yoshika Koinuma, Shin-ichiro Iwakami, Akihiko Iwase, Shinichi Sasaki, Shigeru Tominaga, Kazuhisa Takahashi

Home-based exercise: promising rehabilitation for symptom relief, improved functional status and quality of life for post-surgical lung cancer patients

Amy J. Hoffman, Ruth Ann Brintnall, Alexander von Eye, Lee W. Jones, Gordon Alderink, Lawrence H. Patzelt, Jean K. Brown

Thoracic malignant solitary fibrous tumors: A population-based study of survival

Michael T Milano, Deepinder P Singh, Hong Zhang

Differences in chemosensitivity between primary and paired metastatic lung cancer tissues: In vitro analysis based on the collagen gel droplet embedded culture drug test (CD-DST)

Masahiko Higashiyama, Jiro Okami, Jun Maeda, Toshiteru Tokunaga, Ayako Fujiwara, Ken Kodama, Fumio Imamura, Hisayuki Kobayashi

High-resolution CT findings of patients with pulmonary nocardiosis

Naoki Tsujimoto, Takeshi Saraya, Ken Kikuchi, Saori Takata, Yasuyuki Kurihara, Sayuki Hiraoka, Hiroshi Makino, Shota Yonetani, Koji Araki, Haruyuki Ishii, Hajime Takizawa, Hajime Goto

Signal stratification of autoantibody levels in serum samples and its application to the early detection of lung cancer

Graham F. Healey, Stephen Lam, Peter Boyle, Geoffrey Hamilton-Fairley, Laura J. Peek, John F. R. Robertson

Review Article

Molecular biology of lung cancer

Wendy A. Cooper, David C. L. Lam, Sandra A. O’Toole, John D. Minna

Nontuberculous mycobacterial pulmonary infections

Margaret M. Johnson, John A. Odell

Treatment of advanced non small cell lung cancer

Maria Anna Bareschino, Clorinda Schettino, Antonio Rossi, Paolo Maione, Paola Claudia Sacco, Rosario Zeppa, Cesare Gridelli

Chemotherapy advances in small-cell lung cancer

Bryan A. Chan, Jermaine I. G. Coward

Electromagnetic navigation bronchoscopy: A descriptive analysis

Steven Leong, Hong Ju, Henry Marshall, Rayleen Bowman, Ian Yang, Ann-Maree Ree, Cathy Saxon, Kwun M Fong

Targeted therapy in lung cancer: IPASS and beyond, keeping abreast of the explosion of targeted therapies for lung cancer

Peter Savas, Brett Hughes, Benjamin Solomon

Stereotactic ablative radiotherapy for stage I NSCLC: Recent advances and controversies

Suresh Senan, David A. Palma, Frank J. Lagerwaard

The anticipation and management of air leaks and residual spaces post lung resection

Michael Rolf Mueller, Beatrice A. Marzluf

Exploiting sensitization windows of opportunity in hyper and hypo-fractionated radiation therapy

Anish Prasanna, Mansoor M. Ahmed, Mohammed Mohiuddin, C. Norman Coleman

Ultrasound techniques in the evaluation of the mediastinum, part 2: mediastinal lymph node anatomy and diagnostic reach of ultrasound techniques, clinical work up of neoplastic and inflammatory mediastinal lymphadenopathy using ultrasound techniques and how to learn mediastinal endosonography

Christian Jenssen, Jouke Tabe Annema, Paul Clementsen, Xin-Wu Cui, Mathias Maximilian Borst, Christoph Frank Dietrich

Revisiting signs, strengths and weaknesses of Standard Chest Radiography in patients of Acute Dyspnea in the Emergency Department

Luciano Cardinale, Giovanni Volpicelli, Alessandro Lamorte, Jessica Martino, Andrea veltri

The continuing role of chemotherapy for advanced non-small cell lung cancer in the targeted therapy era

Zarnie Lwin, Jonathan W. Riess, David Gandara

MicroRNAs in mesothelioma: from tumour suppressors and biomarkers to therapeutic targets

Glen Reid

Pleural controversies: image guided biopsy vs. thoracoscopy for undiagnosed pleural effusions?

Giles Dixon, Duneesha de Fonseka, Nick Maskell

Preservation solutions for cardiac and pulmonary donor grafts: a review of the current literature

Nicholas Latchana, Joshua R. Peck, Bryan Whitson, Sylvester M. Black

Active-specific immunotherapy for non-small cell lung cancer

Hauke Winter, Natasja K. van den Engel, Margareta Rusan, Nina Schupp, Christian H. Poehlein, Hong Ming Hu, Rudolf A. Hatz, Walter J. Urba, Karl Walter Jauch, Bernard A. Fox, Dominik Rüttinger

Advanced imaging in COPD: insights into pulmonary pathophysiology

Stephen Milne, Gregory G. King

Advances in lung adenocarcinoma classification: a summary of the new international multidisciplinary classification system (IASLC/ATS/ERS)

Elizabeth R. Tang, Andrew M. Schreiner, Bradley B. Pua

Diagnosis and early detection of COPD using spirometry

David P. Johns, Julia A.E. Walters, E. Haydn Walters

Improving radiotherapy planning, delivery accuracy, and normal tissue sparing using cutting edge technologies

Carri K. Glide-Hurst, Indrin J. Chetty

Pediatric lung transplantation: indications and outcomes

Stephen Kirkby, Don Hayes Jr

Staging lymph node metastases from lung cancer in the mediastinum

Mario D. Terán, Malcolm V. Brock

JTD special edition ‘Hot Topics in COPD’—The microbiome in COPD

Daniel C. Chambers, Shaan L. Gellatly, Philip Hugenholtz, Philip M. Hansbro

Lung donor selection criteria

John Chaney, Yoshikazu Suzuki, Edward Cantu III, Victor van Berkel

Molecular markers to predict clinical outcome and radiation induced toxicity in lung cancer

Joshua D. Palmer, Nicholas G. Zaorsky, Matthew Witek, Bo Lu

Lung cancer screening: identifying the high risk cohort

Michael W. Marcus, Olaide Y. Raji, John K. Field

Pleural controversies: indwelling pleural catheter vs. pleurodesis for malignant pleural effusions

Marc Fortin, Alain Tremblay

New techniques for assessing response after hypofractionated radiotherapy for lung cancer

Sarah A. Mattonen, Kitty Huang, Aaron D. Ward, Suresh Senan, David A. Palma

Supportive and palliative care for lung cancer patients

Patsy Yates, Penelope Schofield, Isabella Zhao, David Currow

Editorial

Stereotactic ablative radiotherapy (SABR) for lung cancer: What does the future hold?

Billy W Loo Jr

Case Report

First report of a novel liquid nitrogen adjustable flow spray cryotherapy (SCT) device in the bronchoscopic treatment of disease of the central tracheo-bronchial airways

Robert Browning, Scott Parrish, Saiyad Sarkar, J. Francis Turner Jr

Severe amiodarone induced pulmonary toxicity

Nicholas Nacca, Castigliano M Bhamidipati, Luke S Yuhico, Sowmya Pinnamaneni, Tamas Szombathy

Guideline

Guidelines for the diagnosis and treatment of malignant pleural mesothelioma

Nico van Zandwijk, Christopher Clarke, Douglas Henderson, A. William Musk, Kwun Fong, Anna Nowak, Robert Loeragan, Brian McCaughan, Michael Boyer, Malcolm Feigen, David Currow, Penelope Schofeild, Beth Ivimey Nick Pavlakis, Jocelyn McLean, Henry Marshall, Steven Leong, Victoria Keena, Andrew Penman

Research Highlight

Gene expression assays as prognostic and predictive markers in early stage non-small cell lung cancer

Tom Donnem, Roy M Bremnes, Lill-Tove Busund, Sigve Andersen, Francesco Pezzella

Short Communication

The sleep apnea cardiovascular endpoints (SAVE) trial: Rationale and start-up phase

R Doug McEvoy, Craig S Anderson, Nick A Antic, Baoyuan Chen, Quanying He, Emma Heeley, Shaoguang Huang, Yining Huang, Jiguang Wang, Nanshan Zhong

Circulating Tumor Cells

Detection methods of circulating tumor cells

Klaus Pantel, Catherine Alix-Panabières

Original Article

Esophageal cancer incidence and mortality in China, 2009

Wanqing Chen, Yutong He, Rongshou Zheng, Siwei Zhang, Hongmei Zeng, Xiaonong Zou, Jie He

Catamenial pneumothorax: a rare entity? Report of 5 cases and review of the literature

Aikaterini N. Visouli, Kaid Darwiche, Andreas Mpakas, Paul Zarogoulidis, Antonios Papagiannis, Kosmas Tsakiridis, Nikolaos Machairiotis, Aikaterini Stylianaki, Nikolaos Katsikogiannis, Nicolaos Courcoutsakis, Konstantinos Zarogoulidis

Clinicopathological and prognostic significance of programmed cell death ligand1 (PD-L1) expression in patients with non-small cell lung cancer: a meta-analysis

Zhen-Kui Pan, Feng Ye, Xuan Wu, Han-Xiang An, Jing-Xun Wu

Nonintubated thoracoscopic lung resection: a 3-year experience with 285 cases in a single institution

Ke-Cheng Chen, Ya-Jung Cheng, Ming-Hui Hung, Yu-Ding Tseng, Jin-Shing Chen

Review Article

Molecular biology of lung cancer

Wendy A. Cooper, David C. L. Lam, Sandra A. O’Toole, John D. Minna

Asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS): current literature review

Antonis Papaiwannou, Paul Zarogoulidis, Konstantinos Porpodis, Dionysios Spyratos, Ioannis Kioumis, Georgia Pitsiou, Athanasia Pataka, Kosmas Tsakiridis, Stamatis Arikas, Andreas Mpakas, Theodora Tsiouda, Nikolaos Katsikogiannis, Ioanna Kougioumtzi, Nikolaos Machairiotis, Stavros Siminelakis, Alexander Kolettas, George Kessis, Thomas Beleveslis, Konstantinos Zarogoulidis

Nontuberculous mycobacterial pulmonary infections

Margaret M. Johnson, John A. Odell

Epidemiology and prognosis of breast cancer in young women

Hussein A. Assi, Katia E. Khoury, Haifa Dbouk, Lana E. Khalil, Tarek H. Mouhieddine, Nagi S. El Saghir

Treatment of non-small cell lung cancer (NSCLC)

Konstantinos Zarogoulidis, Paul Zarogoulidis, Kaid Darwiche, Efimia Boutsikou, Nikolaos Machairiotis, Kosmas Tsakiridis, Nikolaos Katsikogiannis, Ioanna Kougioumtzi, Ilias Karapantzos, Haidong Huang, Dionysios Spyratos

Current management of esophageal cancer

Xavier Benoit D’Journo, Pascal Alexandre Thomas

A review of current and novel therapies for idiopathic pulmonary fibrosis

Rokhsara Rafii, Maya M. Juarez, Timothy E. Albertson, Andrew L. Chan

Pneumothorax after transthoracic needle biopsy of lung lesions under CT guidance

Tatjana Boskovic, Jelena Stanic, Slobodanka Pena-Karan, Paul Zarogoulidis, Kostas Drevelegas, Nikolaos Katsikogiannis, Nikolaos Machairiotis, Andreas Mpakas, Kosmas Tsakiridis, Georgios Kesisis, Theodora Tsiouda, Ioanna Kougioumtzi, Stamatis Arikas, Konstantinos Zarogoulidis

Right heart failure post left ventricular assist device implantation

Mihalis Argiriou, Styliani-Maria Kolokotron, Timothy Sakellaridis, Orestis Argiriou, Christos Charitos, Paul Zarogoulidis, Nikolaos Katsikogiannis, Ioanna Kougioumtzi, Nikolaos Machairiotis, Theodora Tsiouda, Kosmas Tsakiridis, Konstantinos Zarogoulidis

The pivotal role of pathology in the management of lung cancer

Morgan R. Davidson, Adi F. Gazdar, Belinda E. Clarke

Cardiac regeneration: current therapies—future concepts

Stefanie A. Doppler, Marcus-André Deutsch, Rüdiger Lange, Markus Krane

Mechanistic impact of outdoor air pollution on asthma and allergic diseases

Shau-Ku Huang, Qingling Zhang, Zhiming Qiu, Kian Fan Chung

Guideline

Guidelines for the diagnosis and treatment of malignant pleural mesothelioma

Uniportal VATS

Geometrical Characteristics of Uniportal VATS

Luca Bertolaccini, Gaetano Rocco, Andrea Viti, Alberto Terzi

Review Article on Respiratory Sleep Disorders

Obstructive sleep apnea is a common disorder in the population—a review on the epidemiology of sleep apnea

Karl A. Franklin, Eva Lindberg

Review Article on Pollutional Haze

The impact of PM2.5 on the human respiratory system

Yu-Fei Xing, Yue-Hua Xu, Min-Hua Shi, Yi-Xin Lian

Original Article

Suppressive oligonucleotides inhibit inflammation in a murine model of mechanical ventilator induced lung injury

Julia Scheiermann, Dennis M. Klinman

Five-year update on the mouse model of orthotopic lung transplantation: Scientific uses, tricks of the trade, and tips for success

Xue Lin, Wenjun Li, Jiaming Lai, Mikio Okazaki, Seiichiro Sugimoto, Sumiharu Yamamoto, Xingan Wang, Andrew E. Gelman, Daniel Kreisel, Alexander Sasha Krupnick

A pooled analysis of advanced nonsquamous non-small cell lung cancer patients with stable treated brain metastases in two phase II trials receiving bevacizumab and pemetrexed as second-line therapy

Matthew A. Gubens, Jody C. Chuang, Wallace Akerley, Corey J. Langer, Christelle Clément- Duchêne, Melanie San Pedro-Salcedo, A. Dimitrios Colevas, Konstantin Dragnev, Mark A. Socinski, Heather A. Wakelee

Pleurodesis: a comparison of two sclerosing agents for pleural effusions in Mozambique

Ivo Figueiredo, Anilsa Cossa, Anila Hassane, José Sousa, Joaquim Pondo, João Teixeira, Kevan Akrami, Susannah K. Graves, Atul Malhotra, Elizabete A. Nunes

Review Article

Atypical antibody responses to influenza

Dalton Hermans, Richard J. Webby, Sook-San Wong

What can individuals do to reduce personal health risks from air pollution?

Robert Laumbach, Qingyu Meng, Howard Kipen

The role of rotors in atrial fibrillation

David E. Krummen, Vijay Swarup, Sanjiv M. Narayan

Current outcomes of off-pump versus on-pump coronary artery bypass grafting: evidence from randomized controlled trials

Daniel Fudulu, Umberto Benedetto, Gustavo Guida Pecchinenda, Pierpaolo Chivasso, Vito Domenico Bruno, Filippo Rapetto, Alan Bryan, Gianni Davide Angelini

Staging lymph node metastases from lung cancer in the mediastinum

Mario D. Terán, Malcolm V. Brock

Improving radiotherapy planning, delivery accuracy, and normal tissue sparing using cutting edge technologies

Carri K. Glide-Hurst, Indrin J. Chetty

Esophageal cancer: staging system and guidelines for staging and treatment

Mark F. Berry

Implementing the new IASLC/ATS/ERS classification of lung adenocarcinomas: results from international and Chinese cohorts

Ming-Ching Lee, Kyuichi Kadota, Daniel Buitrago, David R. Jones, Prasad S. Adusumilli

Premature menopause in young breast cancer: effects on quality of life and treatment interventions

Shoshana M. Rosenberg, Ann H. Partridge

Strategies for the acquisition of transcriptional and epigenetic information in single cells

Guang Li, Elda Dzilic, Nick Flores, Alice Shieh, Sean M. Wu

The role of transforming growth factor (TGF)-β in the infarcted myocardium

Nikolaos G. Frangogiannis

Utility of cardiac magnetic resonance for evaluation of mitral regurgitation prior to mitral valve surgery

Neil K. Mehta, Jiwon Kim, Jonathan Y. Siden, Sara Rodriguez-Diego, Javid Alakbarli, Antonino Di Franco, Jonathan W. Weinsaft

Adjuvant, neoadjuvant, and definitive radiation therapy for malignant pleural mesothelioma

Gwendolyn Cramer, Charles B. Simone II, Theresa M. Busch, Keith A. Cengel

Editorial

Conservatism strikes back: later is better than earlier dialysis for acute kidney injury

Dana Bielopolski, Kamyar Kalantar-Zadeh

Sleep and critical illness: bridging the two pillars at the ATS 2016

Stuti J. Jaiswal, Atul Malhotra, Robert L. Owens

Temperature and duration targets during post-arrest care: choosing the right prescription for the right patient

John C. Greenwood, Abhishek Bhardwaj, Benjamin S. Abella

Examining the paradox of high high-density lipoprotein and elevated cardiovascular risk

Kavisha Singh, Anand Rohatgi

Mortality after red blood cell transfusions from previously pregnant donors: complexities in the interpretation of large data

Susan Kuldanek, Christopher C. Silliman

Optogenetic tools for cell biological applications

Abhirup Mukherjee, Nicole A. Repina, David V. Schaffer, Ravi S. Kane

Editorial on “Transcription factor SPZ1 promotes TWIST-mediated epithelial—mesenchymal transition and oncogenesis in human liver cancer”

Dan J. Raz

Editorial on “Can CT-PET and endoscopic assessment post-neoadjuvant chemoradiotherapy predict residual disease in esophageal cancer”

Chia-Ju Liu, Wei Lu

The hemodynamic impact of acute nasal continuous positive airway pressure treatment in hypertrophic cardiomyopathy: is it safe?

Bo Xu, Reena Mehra

Tumor spread through air space (STAS) is an important predictor of clinical outcome in stage IA lung adenocarcinoma

Hui-Zi Chen, Erin M. Bertino, Kai He

Antiviral prophylaxis of cytomegalovirus reactivation in immune competent patients—the jury remains out

Sara A. Mansfield, Charles H. Cook

Allosterically targeting EGFR drug-resistance gatekeeper mutations

Nicholas Spellmon, Chunying Li, Zhe Yang

Imaging homeostatic sleep pressure and circadian rhythm in the human brain

Zhuo Fang, Hengyi Rao

Tumor mutational burden (TMB) as a biomarker of response to immunotherapy in small cell lung cancer

Yanis Boumber

Letter to the Editor

Response to “VATS vs. thoracotomy regarding postoperative chronic pain”

Emine Ozgur Bayman, Kalpaj R. Parekh, John Keech, Timothy J. Brennan

The role of a decision analysis in treatment of T2N0 esophageal cancer

Tara R. Semenkovich, Bryan F. Meyers, Benjamin D. Kozower, Varun Puri

Case Report

Intraoperative near-infrared imaging can identify subcentimeter colorectal cancer lung metastases during pulmonary metastasectomy

Andrew D. Newton, Jarrod D. Predina, Lydia G. Frenzel-Sulyok, Michael H. Shin, Yiqing Wang, Sunil Singhal

A novel strategy for cardiopulmonary support during lung transplantation

Ramiro Fernandez, Malcolm M. DeCamp, Ankit Bharat

Short Communication

Predictive value of pulmonary function measures for short-term outcomes following lung resection: analysis of a single high-volume institution

Lauren J. Taylor, Walker A. Julliard, James D. Maloney

Review Article on Left Ventricular Assist Devices

Left ventricular assist device driveline infections: recent advances and future goals

Anne-Marie Leuck

Short Communication of Interventional Pulmonology Corner

Endobronchial ultrasound—guidance for interstitial photodynamic therapy of locally advanced lung cancer—a new interventional concept

Kassem Harris, Emily Oakley, David Bellnier, Gal Shafirstein

Commentary

Insights into ascending aortic aneurysm pathogenesis using in vivo and ex vivo imaging systems in angiotensin II-infused mice

Mary B. Sheppard, Alan Daugherty, Hong Lu

Management of screening-detected stage I lung cancer

Raymond U. Osarogiagbon

New strategies in esophageal carcinoma: promises and problems

Zhaohui Xiong, Jingxi He, Xiaoxin Luke Chen

Below are the latest Journal of Thoracic Disease articles published online ahead of print publication.

Original Article

Comparison of clinical effects between regional arterial embolization combined with surgery and simple surgery in the treatment of tuberculosis-destroyed lung—a retrospective comparative cohort study

Xiaolin Wang, Nan Jiang, Zhengxun Zhang, Lu Han

Published online: 24 March 2023

Original Article

Perioperative outcomes of neoadjuvant immunotherapy plus chemotherapy and neoadjuvant chemoradiotherapy in the treatment of locally advanced esophageal squamous cell carcinoma: a retrospective comparative cohort study

Hai Zhang, Zhenyang Zhang, Litao Yang, Bomeng Wu, Ying Chen, Haiquan He, Cui Li, Wanli Lin, Jiangbo Lin

Published online: 24 March 2023

Original Article

Long-term outcomes after coronary artery bypass graft with or without surgical ventricular reconstruction in patients with severe left ventricular dysfunction

Tao Yang, Xin Yuan, Baotong Li, Shihua Zhao, Hansong Sun, Minjie Lu

Published online: 23 March 2023

Original Article

Predictors associated with mortality of veno-venous extracorporeal membrane oxygenation therapy

Elena Neumann, Sebastian D. Sahli, Alexander Kaserer, Julia Braun, Muriel A. Spahn, Raed Aser, Donat R. Spahn, Markus J. Wilhelm

Published online: 22 March 2023

Editorial

Need for preoperative marking of pulmonary nodules and a more useful technique

Yuka Shinohara, Masahide Oki

Published online: 22 March 2023

Editorial

Hybrid video-assisted thoracoscopic sleeve lobectomy: an elegant minimally invasive technique for locally advanced non-small cell lung cancer

Alexis P. Chidi, Mara B. Antonoff

Published online: 22 March 2023

Original Article

Preoperative detection of pleural adhesions using dynamic chest radiography: prospective analysis

Takuya Watanabe, Eriko Suzuki, Naoko Yoshii, Hiroyuki Tsuchida, Shogo Yobita, Suiha Uchiyama, Kensuke Iguchi, Minori Nakamura, Takumi Endo, Masayuki Tanahashi

Published online: 22 March 2023

Original Article

Influence of hepatic dysfunction in patients who underwent tricuspid valve surgery

Mi Hee Lim, Chee-Hoon Lee, Min Ho Ju, Hyung Gon Je

Published online: 22 March 2023

Editorial

About a new pleural digital drainage system, the Thoraguard device

Julien Epailly, Alex Fourdrain

Published online: 21 March 2023

Original Article

Impact of delayed transition off intravenous vasoactive agents for aortic dissection on intensive care unit length of stay

Noelle De Leon, Gabriela Young, Dexter Wimer

Published online: 20 March 2023

Original Article

Surgery for thoracic oligoprogression in metastatic renal cell cancer in the era of new systemic therapies

Uyen-Thao Le, Bernward Passlick, Severin Schmid

Published online: 20 March 2023

Editorial

Pediatric chylothorax: Where we’ve been and where we’re going

Melissa Winder, David Bailly

Published online: 20 March 2023

Brief Report

Real-time assessment of COVID-19 epidemic in Guangdong Province, China using mathematical models

Zhiqi Zeng, Wei Qu, Ruibin Liu, Wenda Guan, Jingyi Liang, Zhijie Lin, Eric H. Y. Lau, Chitin Hon, Zifeng Yang, Jianxing He

Published online: 20 March 2023

Original Article

Preoperative umeclidinium/vilanterol or tiotropium improves postoperative FEV₁ in lung cancer patients with comorbid untreated chronic obstructive pulmonary disease

Takahiro Homma

Published online: 20 March 2023

Original Article

Features of osteoporosis in male patients with bronchiectasis, a cross-sectional study

Gang Xu, Jun Zhao, Feng Liu, Danyan Cai, Congrui Feng, Liuqian Wang, Yanjun Zeng, Yuanling Liu, Sizhi Wu, Yuluo Chen, Wei Ma

Published online: 15 March 2023

Original Article

Efficacy and safety of immune checkpoint inhibitors versus chemotherapy in the second-line treatment of advanced esophageal squamous cell carcinoma: a meta-analysis and systematic review

Kanghao Zhu, Hui Chen, Congcong Xu, Dong Chen, Zixian Jin, Sijia Ren, Pasan Witharana, Baofu Chen, Jianfei Shen

Published online: 15 March 2023

Surgical Technique

Improved complete portal 4-port robotic lobectomy for lung cancer: Hamamatsu Method KAI

Kazuhito Funai, Akikazu Kawase, Yusuke Takanashi, Kiyomichi Mizuno, Norihiko Shiiya

Published online: 15 March 2023

Original Article

Simplified total arch reconstruction with a stented graft for extended aortic arch dilation

Hua-Jie Zheng, San-Jiu Yu, De-Qing Lin, Yi-Bing Fang, Yong-Bo Cheng, Chao-Jun Yan, Jiao Xu, Xin Liu, Xian-Pu Zhang, Ling-Feng Tang, Jun Li, Ping He, Wei Cheng

Published online: 14 March 2023

Editorial

Time is ticking: the role of time after primary transplant and functional impairment on survival after redo lung transplant

Michael T. Olson, Ariba Moin, Tejus Walia, Ashwini Arjuna

Published online: 14 March 2023

Original Article

Narrowing the therapeutic window?—A case-control study on the influence of the COVID-19 pandemic on the primary UICC stage of NSCLC

Isabella B. Metelmann, Sebastian Kraemer, Matthias Steinert, Stephan Kersting, Alexandra Busemann

Published online: 13 March 2023

Original Article

Multi-level analysis and evaluation of organizational improvements in Thoracic Surgery according to a Value-Based HealthCare approach

Riccardo Orlandi, Marco Scarci, Ugo Cioffi, Angelo Guttadauro, Gianluca Peschi, Enrico Mario Cassina, Pierluigi Filosso, Federico Raveglia

Published online: 13 March 2023

Original Article

Clinicopathological features and surgical outcomes of lobectomy combined with segmentectomy: a cohort study

Seshiru Nakazawa, Kimihiro Shimizu, Tomohiro Yazawa, Natsuko Kawatani, Kai Obayashi, Yoichi Ohtaki, Takayuki Kosaka, Toshiki Yajima, Ken Shirabe

Published online: 13 March 2023

Original Article

Esophageal stenting with minimally-invasive surgical intervention for delayed spontaneous esophageal perforation

Chien-Hung Chiu, Osbert Qi Yao Leow, Yu-Chao Wang, Wei-Hsun Chen, Hsin-Yueh Fang, Yin-Kai Chao, Jules Lin

Published online: 10 March 2023

Original Article

CT-based decision tree model for predicting EGFR mutation status in synchronous multiple primary lung cancers

Yingwei Luo, Shuangjiang Li, Huiyun Ma, Wenbiao Zhang, Baocong Liu, Chuanmiao Xie, Qiong Li

Published online: 09 March 2023

Letter to the Editor

Small pleural holes of the apical parietal pleura: an unknown precursors of cervical lung hernia and association with primary spontaneous pneumothorax

Domenico Galetta, Maria Serra, Lorenzo Spaggiari

Published online: 09 March 2023

Original Article

Prediction models for respiratory outcomes in patients with COVID-19: integration of quantitative computed tomography parameters, demographics, and laboratory features

Jieun Kang, Jiyeon Kang, Woo Jung Seo, So Hee Park, Hyung Koo Kang, Hye Kyeong Park, JongHoon Hyun, Je Eun Song, Yee Gyung Kwak, Ki Hwan Kim, Yeon Soo Kim, Sung-Soon Lee, Hyeon-Kyoung Koo

Published online: 09 March 2023

Original Article

Long-term follow up and comparison between conservative and interventional therapy in postoperative bronchopleural fistula—a cohort study

Yinghua Wang, Minfang Zhu, Yan Pan, Kaiyan Yu

Published online: 09 March 2023

Review Article

Current use of extracorporeal life support (ECLS) in airway surgery: a narrative review

Alexis Slama, Theresa Stork, Stephane Collaud, Clemens Aigner

Published online: 07 March 2023

Editorial