Optimizations of stent and tissue leaflets in a new surgical bovine pericardial valve

Jinmiao Chen, Jun Yang, Li Zhang, Wenrui Ma, Shuyang Lu, Chunsheng Wang, Tao Hong


Compared with mechanical valves, bovine pericardial valves have satisfactory hemodynamic performance, low risk of infective endocarditis, and low incidence of thromboembolism without long-term anticoagulation treatment (1). Even after decades of continues improvements in tissue leaflets and bioprosthetic valve structure, the existing bioprosthetic valves still have some drawbacks. Although mid- and long-term clinical outcomes of bovine pericardial valves are satisfactory in the literature, the durability is still a major concern because of structural valve deterioration (SVD) (2-6).