Editorial


The challenge of prognostic markers in pleural mesothelioma

Andrea Imperatori, Massimo Castiglioni, Lorenzo Mortara, Elisa Nardecchia, Nicola Rotolo

Abstract

Malignant pleural mesothelioma (MPM) is a very aggressive tumor, highly resistant to chemo- and radio-therapy. Treatment of MPM patients is often disappointing, regardless of the modality used.
Inter-individual variability of response to multimodal treatment remains a challenge and generally the MPM prognosis continues to be poor. Knowledge of predicting factors of outcome is currently insufficient; therefore, it would be highly desirable to find specific prognostic markers for MPM. Translational research projects are to be implemented.

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