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ICC Column more

Sleep complaints and sleep breathing disorders in upper and lower obstructive lung diseases

Matteo Ferrando, Diego Bagnasco, Valeria Roustan, Giorgio Walter Canonica, Fulvio Braido, Ilaria... More >>

Cough Section more

Clinical Practice Guidelines for Diagnosis and Management of Cough—Chinese Thoracic Society (CTS) Asthma Consortium

Kefang Lai, Huahao Shen, Xin Zhou, Zhongmin Qiu, Shaoxi Cai, Kewu Huang, Qiuping Wang, Changzheng... More >>

Cough frequency monitors: can they discriminate patient from environmental coughs?

Stefan T. Kulnik, Natalie M. Williams, Lalit Kalra, John Moxham, Surinder S. Birring More >>

Endorsement

Endorsement

Journal of Thoracic Disease is endorsed by International COPD Coalition.

Endorsement

The China Asthma Alliance

Endorsement

The Brazilian Society of Thoracic Surgery (SBCT)

Italian Society of Thoracic Surgery

The Italian Society of Thoracic Surgery (SICT)

Italian VATS Group

The Italian VATS Group:

Global Alliance against Chronic Respiratory Diseases (GARD)

Global Alliance against Chronic Respiratory Diseases (GARD)

Surgical Technique

Hybrid operating room—one stop for diagnosis, staging and treatment of early stage NSCLC
Joyce W. Y. Chan, Peter S. Y. Yu, Rainbow W. H. Lau, Calvin S. H. Ng

Review Article

Molecular biology of lung cancer
Wendy A. Cooper, David C. L. Lam, Sandra A. O’Toole, John D. Minna
Nontuberculous mycobacterial pulmonary infections
Margaret M. Johnson, John A. Odell
Treatment of advanced non small cell lung cancer
Maria Anna Bareschino, Clorinda Schettino, Antonio Rossi, Paolo Maione, Paola Claudia Sacco, Rosario Zeppa, Cesare Gridelli
Chemotherapy advances in small-cell lung cancer
Bryan A. Chan, Jermaine I. G. Coward
Electromagnetic navigation bronchoscopy: A descriptive analysis
Steven Leong, Hong Ju, Henry Marshall, Rayleen Bowman, Ian Yang, Ann-Maree Ree, Cathy Saxon, Kwun M Fong
Targeted therapy in lung cancer: IPASS and beyond, keeping abreast of the explosion of targeted therapies for lung cancer
Peter Savas, Brett Hughes, Benjamin Solomon
Stereotactic ablative radiotherapy for stage I NSCLC: Recent advances and controversies
Suresh Senan, David A. Palma, Frank J. Lagerwaard
The anticipation and management of air leaks and residual spaces post lung resection
Michael Rolf Mueller, Beatrice A. Marzluf
Exploiting sensitization windows of opportunity in hyper and hypo-fractionated radiation therapy
Anish Prasanna, Mansoor M. Ahmed, Mohammed Mohiuddin, C. Norman Coleman
Ultrasound techniques in the evaluation of the mediastinum, part 2: mediastinal lymph node anatomy and diagnostic reach of ultrasound techniques, clinical work up of neoplastic and inflammatory mediastinal lymphadenopathy using ultrasound techniques and how to learn mediastinal endosonography
Christian Jenssen, Jouke Tabe Annema, Paul Clementsen, Xin-Wu Cui, Mathias Maximilian Borst, Christoph Frank Dietrich
Revisiting signs, strengths and weaknesses of Standard Chest Radiography in patients of Acute Dyspnea in the Emergency Department
Luciano Cardinale, Giovanni Volpicelli, Alessandro Lamorte, Jessica Martino, Andrea veltri
The continuing role of chemotherapy for advanced non-small cell lung cancer in the targeted therapy era
Zarnie Lwin, Jonathan W. Riess, David Gandara
MicroRNAs in mesothelioma: from tumour suppressors and biomarkers to therapeutic targets
Glen Reid
Pleural controversies: image guided biopsy vs. thoracoscopy for undiagnosed pleural effusions?
Giles Dixon, Duneesha de Fonseka, Nick Maskell
Preservation solutions for cardiac and pulmonary donor grafts: a review of the current literature
Nicholas Latchana, Joshua R. Peck, Bryan Whitson, Sylvester M. Black
Active-specific immunotherapy for non-small cell lung cancer
Hauke Winter, Natasja K. van den Engel, Margareta Rusan, Nina Schupp, Christian H. Poehlein, Hong Ming Hu, Rudolf A. Hatz, Walter J. Urba, Karl Walter Jauch, Bernard A. Fox, Dominik Rüttinger
Advanced imaging in COPD: insights into pulmonary pathophysiology
Stephen Milne, Gregory G. King
Advances in lung adenocarcinoma classification: a summary of the new international multidisciplinary classification system (IASLC/ATS/ERS)
Elizabeth R. Tang, Andrew M. Schreiner, Bradley B. Pua
Diagnosis and early detection of COPD using spirometry
David P. Johns, Julia A.E. Walters, E. Haydn Walters
Improving radiotherapy planning, delivery accuracy, and normal tissue sparing using cutting edge technologies
Carri K. Glide-Hurst, Indrin J. Chetty
Pediatric lung transplantation: indications and outcomes
Stephen Kirkby, Don Hayes Jr
Staging lymph node metastases from lung cancer in the mediastinum
Mario D. Terán, Malcolm V. Brock
JTD special edition ‘Hot Topics in COPD’—The microbiome in COPD
Daniel C. Chambers, Shaan L. Gellatly, Philip Hugenholtz, Philip M. Hansbro
Lung donor selection criteria
John Chaney, Yoshikazu Suzuki, Edward Cantu III, Victor van Berkel
Molecular markers to predict clinical outcome and radiation induced toxicity in lung cancer
Joshua D. Palmer, Nicholas G. Zaorsky, Matthew Witek, Bo Lu
Lung cancer screening: identifying the high risk cohort
Michael W. Marcus, Olaide Y. Raji, John K. Field
Pleural controversies: indwelling pleural catheter vs. pleurodesis for malignant pleural effusions
Marc Fortin, Alain Tremblay
New techniques for assessing response after hypofractionated radiotherapy for lung cancer
Sarah A. Mattonen, Kitty Huang, Aaron D. Ward, Suresh Senan, David A. Palma
Supportive and palliative care for lung cancer patients
Patsy Yates, Penelope Schofield, Isabella Zhao, David Currow

Original Article

Nonintubated thoracoscopic lung resection: a 3-year experience with 285 cases in a single institution
Ke-Cheng Chen, Ya-Jung Cheng, Ming-Hui Hung, Yu-Ding Tseng, Jin-Shing Chen
Delays in the diagnosis of lung cancer
Peter M Ellis, Rachel Vandermeer
The diagnostic utility of endobronchial ultrasonography with a guide sheath and tomosynthesis images for ground glass opacity pulmonary lesions
Takehiro Izumo, Shinji Sasada, Christine Chavez, Takaaki Tsuchida
Hydration with magnesium and mannitol without furosemide prevents the nephrotoxicity induced by cisplatin and pemetrexed in patients with advanced non-small cell lung cancer
Keiko Muraki, Ryo Koyama, Yuichiro Honma, Shigehiro Yagishita, Takehito Shukuya, Rina Ohashi, Fumiyuki Takahashi, Kenji Kido, Shin-ichiro Iwakami, Shinichi Sasaki, Akihiko Iwase, Kazuhisa Takahashi
Local control rates with five-fraction stereotactic body radiotherapy for oligometastatic cancer to the lung
Deepinder Singh, Yuhchyau Chen, Mary Z. Hare, Kenneth Y. Usuki, Hong Zhang, Thomas Lundquist, Neil Joyce, Michael C. Schell, Michael T. Milano
Theoretical models of carcinogenic particle deposition and clearance in children’s lungs
Robert Sturm
A novel paradigm in the treatment of oligometastatic non-small cell lung cancer
Salma K Jabbour, Parima Daroui, Dirk Moore, Edward Licitra, Molly Gabel, Joseph Aisner
Radiotherapy for a second primary lung cancer arising post-pneumonectomy: planning considerations and clinical outcomes
Sashendra Senthi, Cornelis J. A. Haasbeek, Frank J. Lagerwaard, Wilko F. Verbakel, Patricia F. de Haan, Ben J. Slotman, Suresh Senan
Impact of metformin use on survival in locally-advanced, inoperable non-small cell lung cancer treated with definitive chemoradiation
Inaya Ahmed, Adam Ferro, Alan Cohler, John Langenfeld, Sujani G. Surakanti, Joseph Aisner, Wei Zou, Bruce G. Haffty, Salma K. Jabbour
Utility of EBUS-TBNA for diagnosis of mediastinal tuberculous lymphadenitis: a multicentre Australian experience
James Geake, Gary Hammerschlag, Phan Nguyen, Peter Wallbridge, Grant A. Jenkin, Tony M. Korman, Barton Jennings, Douglas F. Johnson, Louis B. Irving, Michael Farmer, Daniel P. Steinfort
Comparative outcomes of squamous and non-squamous non-small cell lung cancer (NSCLC) patients in phase II studies of ASA404 (DMXAA) – retrospective analysis of pooled data
Mark J McKeage, Michael B Jameson, AS1404-201 Study Group Investigators
High prevalence of gene abnormalities in young patients with lung cancer
Osamu Nagashima, Rina Ohashi, Yasuko Yoshioka, Ai Inagaki, Manabu Tajima, Yoshika Koinuma, Shin-ichiro Iwakami, Akihiko Iwase, Shinichi Sasaki, Shigeru Tominaga, Kazuhisa Takahashi
Home-based exercise: promising rehabilitation for symptom relief, improved functional status and quality of life for post-surgical lung cancer patients
Amy J. Hoffman, Ruth Ann Brintnall, Alexander von Eye, Lee W. Jones, Gordon Alderink, Lawrence H. Patzelt, Jean K. Brown
Thoracic malignant solitary fibrous tumors: A population-based study of survival
Michael T Milano, Deepinder P Singh, Hong Zhang
Differences in chemosensitivity between primary and paired metastatic lung cancer tissues: In vitro analysis based on the collagen gel droplet embedded culture drug test (CD-DST)
Masahiko Higashiyama, Jiro Okami, Jun Maeda, Toshiteru Tokunaga, Ayako Fujiwara, Ken Kodama, Fumio Imamura, Hisayuki Kobayashi
High-resolution CT findings of patients with pulmonary nocardiosis
Naoki Tsujimoto, Takeshi Saraya, Ken Kikuchi, Saori Takata, Yasuyuki Kurihara, Sayuki Hiraoka, Hiroshi Makino, Shota Yonetani, Koji Araki, Haruyuki Ishii, Hajime Takizawa, Hajime Goto
Signal stratification of autoantibody levels in serum samples and its application to the early detection of lung cancer
Graham F. Healey, Stephen Lam, Peter Boyle, Geoffrey Hamilton-Fairley, Laura J. Peek, John F. R. Robertson

Case Report

First report of a novel liquid nitrogen adjustable flow spray cryotherapy (SCT) device in the bronchoscopic treatment of disease of the central tracheo-bronchial airways
Robert Browning, Scott Parrish, Saiyad Sarkar, J. Francis Turner Jr
Severe amiodarone induced pulmonary toxicity
Nicholas Nacca, Castigliano M Bhamidipati, Luke S Yuhico, Sowmya Pinnamaneni, Tamas Szombathy

Guideline

Guidelines for the diagnosis and treatment of malignant pleural mesothelioma
Nico van Zandwijk, Christopher Clarke, Douglas Henderson, A. William Musk, Kwun Fong, Anna Nowak, Robert Loeragan, Brian McCaughan, Michael Boyer, Malcolm Feigen, David Currow, Penelope Schofeild, Beth Ivimey Nick Pavlakis, Jocelyn McLean, Henry Marshall, Steven Leong, Victoria Keena, Andrew Penman

Research Highlight

Gene expression assays as prognostic and predictive markers in early stage non-small cell lung cancer
Tom Donnem, Roy M Bremnes, Lill-Tove Busund, Sigve Andersen, Francesco Pezzella

Short Communication

The sleep apnea cardiovascular endpoints (SAVE) trial: Rationale and start-up phase
R Doug McEvoy, Craig S Anderson, Nick A Antic, Baoyuan Chen, Quanying He, Emma Heeley, Shaoguang Huang, Yining Huang, Jiguang Wang, Nanshan Zhong

Circulating Tumor Cells

Detection methods of circulating tumor cells
Klaus Pantel, Catherine Alix-Panabières

Review Article

Atypical antibody responses to influenza
Dalton Hermans, Richard J. Webby, Sook-San Wong
What can individuals do to reduce personal health risks from air pollution?
Robert Laumbach, Qingyu Meng, Howard Kipen
The role of rotors in atrial fibrillation
David E. Krummen, Vijay Swarup, Sanjiv M. Narayan
Current outcomes of off-pump versus on-pump coronary artery bypass grafting: evidence from randomized controlled trials
Daniel Fudulu, Umberto Benedetto, Gustavo Guida Pecchinenda, Pierpaolo Chivasso, Vito Domenico Bruno, Filippo Rapetto, Alan Bryan, Gianni Davide Angelini
Staging lymph node metastases from lung cancer in the mediastinum
Mario D. Terán, Malcolm V. Brock
Improving radiotherapy planning, delivery accuracy, and normal tissue sparing using cutting edge technologies
Carri K. Glide-Hurst, Indrin J. Chetty
Esophageal cancer: staging system and guidelines for staging and treatment
Mark F. Berry
Implementing the new IASLC/ATS/ERS classification of lung adenocarcinomas: results from international and Chinese cohorts
Ming-Ching Lee, Kyuichi Kadota, Daniel Buitrago, David R. Jones, Prasad S. Adusumilli
Premature menopause in young breast cancer: effects on quality of life and treatment interventions
Shoshana M. Rosenberg, Ann H. Partridge
Strategies for the acquisition of transcriptional and epigenetic information in single cells
Guang Li, Elda Dzilic, Nick Flores, Alice Shieh, Sean M. Wu
The role of transforming growth factor (TGF)-β in the infarcted myocardium
Nikolaos G. Frangogiannis
Utility of cardiac magnetic resonance for evaluation of mitral regurgitation prior to mitral valve surgery
Neil K. Mehta, Jiwon Kim, Jonathan Y. Siden, Sara Rodriguez-Diego, Javid Alakbarli, Antonino Di Franco, Jonathan W. Weinsaft
Adjuvant, neoadjuvant, and definitive radiation therapy for malignant pleural mesothelioma
Gwendolyn Cramer, Charles B. Simone II, Theresa M. Busch, Keith A. Cengel

Original Article

Suppressive oligonucleotides inhibit inflammation in a murine model of mechanical ventilator induced lung injury
Julia Scheiermann, Dennis M. Klinman
Five-year update on the mouse model of orthotopic lung transplantation: Scientific uses, tricks of the trade, and tips for success
Xue Lin, Wenjun Li, Jiaming Lai, Mikio Okazaki, Seiichiro Sugimoto, Sumiharu Yamamoto, Xingan Wang, Andrew E. Gelman, Daniel Kreisel, Alexander Sasha Krupnick
A pooled analysis of advanced nonsquamous non-small cell lung cancer patients with stable treated brain metastases in two phase II trials receiving bevacizumab and pemetrexed as second-line therapy
Matthew A. Gubens, Jody C. Chuang, Wallace Akerley, Corey J. Langer, Christelle Clément- Duchêne, Melanie San Pedro-Salcedo, A. Dimitrios Colevas, Konstantin Dragnev, Mark A. Socinski, Heather A. Wakelee
Pleurodesis: a comparison of two sclerosing agents for pleural effusions in Mozambique
Ivo Figueiredo, Anilsa Cossa, Anila Hassane, José Sousa, Joaquim Pondo, João Teixeira, Kevan Akrami, Susannah K. Graves, Atul Malhotra, Elizabete A. Nunes

Case Report

Intraoperative near-infrared imaging can identify subcentimeter colorectal cancer lung metastases during pulmonary metastasectomy
Andrew D. Newton, Jarrod D. Predina, Lydia G. Frenzel-Sulyok, Michael H. Shin, Yiqing Wang, Sunil Singhal
A novel strategy for cardiopulmonary support during lung transplantation
Ramiro Fernandez, Malcolm M. DeCamp, Ankit Bharat

Editorial

Conservatism strikes back: later is better than earlier dialysis for acute kidney injury
Dana Bielopolski, Kamyar Kalantar-Zadeh
Sleep and critical illness: bridging the two pillars at the ATS 2016
Stuti J. Jaiswal, Atul Malhotra, Robert L. Owens
Temperature and duration targets during post-arrest care: choosing the right prescription for the right patient
John C. Greenwood, Abhishek Bhardwaj, Benjamin S. Abella
Examining the paradox of high high-density lipoprotein and elevated cardiovascular risk
Kavisha Singh, Anand Rohatgi
Mortality after red blood cell transfusions from previously pregnant donors: complexities in the interpretation of large data
Susan Kuldanek, Christopher C. Silliman
Optogenetic tools for cell biological applications
Abhirup Mukherjee, Nicole A. Repina, David V. Schaffer, Ravi S. Kane
Editorial on “Transcription factor SPZ1 promotes TWIST-mediated epithelial—mesenchymal transition and oncogenesis in human liver cancer”
Dan J. Raz
Editorial on “Can CT-PET and endoscopic assessment post-neoadjuvant chemoradiotherapy predict residual disease in esophageal cancer”
Chia-Ju Liu, Wei Lu
The hemodynamic impact of acute nasal continuous positive airway pressure treatment in hypertrophic cardiomyopathy: is it safe?
Bo Xu, Reena Mehra
Tumor spread through air space (STAS) is an important predictor of clinical outcome in stage IA lung adenocarcinoma
Hui-Zi Chen, Erin M. Bertino, Kai He
Antiviral prophylaxis of cytomegalovirus reactivation in immune competent patients—the jury remains out
Sara A. Mansfield, Charles H. Cook
Allosterically targeting EGFR drug-resistance gatekeeper mutations
Nicholas Spellmon, Chunying Li, Zhe Yang
Imaging homeostatic sleep pressure and circadian rhythm in the human brain
Zhuo Fang, Hengyi Rao
Tumor mutational burden (TMB) as a biomarker of response to immunotherapy in small cell lung cancer
Yanis Boumber

Letter to the Editor

Response to “VATS vs. thoracotomy regarding postoperative chronic pain”
Emine Ozgur Bayman, Kalpaj R. Parekh, John Keech, Timothy J. Brennan
The role of a decision analysis in treatment of T2N0 esophageal cancer
Tara R. Semenkovich, Bryan F. Meyers, Benjamin D. Kozower, Varun Puri

Review Article on Left Ventricular Assist Devices

Left ventricular assist device driveline infections: recent advances and future goals
Anne-Marie Leuck

Short Communication of Interventional Pulmonology Corner

Endobronchial ultrasound—guidance for interstitial photodynamic therapy of locally advanced lung cancer—a new interventional concept
Kassem Harris, Emily Oakley, David Bellnier, Gal Shafirstein

Below are the latest Journal of Thoracic Disease articles published online ahead of print publication.

Review Article

The European experience
Davide Tosi, Alessandro Palleschi, Valeria Musso, Alessandra Mazzucco, Margherita Cattaneo, Rosaria Carrinola, Francesco Damarco, Paolo Mendogni

Original Article



Letter to the Editor


Short Communication



Study Protocol

Treatment rationale and design of the PROLONG study: safety and efficacy of pembrolizumab as first-line therapy for elderly patients with non-small cell lung cancer
Takeshi Masuda, Kazunori Fujitaka, Nobuhisa Ishikawa, Kikuo Nakano, Masahiro Yamasaki, Souichi Kitaguchi, Ken Masuda, Kakuhiro Yamaguchi, Shinjiro Sakamoto, Yasushi Horimasu, Shigeo Kawase, Shintaro Miyamoto, Taku Nakashima, Hiroshi Iwamoto, Naoki Shiota, Tadashi Senoo, Yoshikazu Awaya, Tomohiro Kondo, Takashi Yoshida, Hironobu Hamada, Isao Murakami, Noboru Hattori