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Sleep complaints and sleep breathing disorders in upper and lower obstructive lung diseases

Matteo Ferrando, Diego Bagnasco, Valeria Roustan, Giorgio Walter Canonica, Fulvio Braido, Ilaria... More >>

Cough Section more

Clinical Practice Guidelines for Diagnosis and Management of Cough—Chinese Thoracic Society (CTS) Asthma Consortium

Kefang Lai, Huahao Shen, Xin Zhou, Zhongmin Qiu, Shaoxi Cai, Kewu Huang, Qiuping Wang, Changzheng... More >>

Cough frequency monitors: can they discriminate patient from environmental coughs?

Stefan T. Kulnik, Natalie M. Williams, Lalit Kalra, John Moxham, Surinder S. Birring More >>



Journal of Thoracic Disease is endorsed by International COPD Coalition.


The China Asthma Alliance


The Brazilian Society of Thoracic Surgery (SBCT)

Italian Society of Thoracic Surgery

The Italian Society of Thoracic Surgery (SICT)

Italian VATS Group

The Italian VATS Group:

Global Alliance against Chronic Respiratory Diseases (GARD)

Global Alliance against Chronic Respiratory Diseases (GARD)


Awake extracorporeal membrane oxygenation in immunosuppressed patients with severe respiratory failure—a stretch too far?
Kiran Shekar, Darryl Abrams, Matthieu Schmidt
Extracorporeal membrane oxygenation in traumatic tracheal injuries: a bold life-saving option
Vittorio Aprile, Stylianos Korasidis, Marcello Carlo Ambrogi, Marco Lucchi
Management of non-small cell lung cancer harboring epidermal growth factor receptor mutations in the era of first-line osimertinib
Taiki Hakozaki, Yusuke Okuma
Acute adverse drug reactions with contrast media after cardiac catheterization: can we identify those at risk?
Dhruv Mahtta, Ankur Jain, Islam Y. Elgendy
Predicting contrast induced nephropathy in patients undergoing percutaneous coronary intervention
Rebecca Gosling, Javaid Iqbal
Sometimes neither water nor fire are more useful than friendship—a new risk score for prediction of contrast-induced nephropathy (CIN) and long-term adverse outcomes in patients undergoing coronary angiography
Ovidio De Filippo, Fabrizio D’Ascenzo, Francesco Piroli, Carlo Budano, Gaetano Maria De Ferrari
Acute adverse drug reactions following cardiac catheterization: evidence-based guidance for providers and systems
Spencer W. Trooboff, Alexander Iribarne
Proportion of lung adenocarcinoma in female never-smokers has increased dramatically over the past 28 years
Cuicui Huang, Xiao Qu, Jiajun Du
Contrast induced acute kidney injury and the role of beta-blockers in its prevention
Umberto Barbero, Mario Iannaccone, Michele De Benedictis, Baldassarre Doronzo
Thymoma surgery: extreme surgical indications
Pierluigi Novellis, Giulia Veronesi, Zaheer Raffeeq, Marco Alloisio
Predicting acute adverse contrast mean reactions following cardiac catheterization: a complex undertaking
Marco Di Maio, Davide Capodanno

Original Article

Feedback on the use of three surgical sealants for preventing prolonged air leak after robot-assisted anatomical lung resection
Henri Gondé, Constance Le Gac, André Gillibert, Benjamin Bottet, Marc Laurent, Matthieu Sarsam, Charles Hervouët, Rémi Varin, Jean-Marc Baste
Clinico-bacteriological analysis for video-assisted thoracoscopic biopsy of non-tuberculous mycobacteria
Takashi Yamamichi, Hirotoshi Horio, Ayaka Asakawa, Masayuki Okui, Masahiko Harada
Evaluation of a novel collagen hemostatic matrix in a porcine heart and cardiac vessel injury model
Heemoon Lee, Jun Ho Lee, Chang-Seok Jeon, Jae Hyung Ko, Si-Nae Park, Young Tak Lee
Diagnostic value of CD206+CD14+ macrophages in diagnosis of lung cancer originated malignant pleural effusion
Xue-Bin Pei, Xiu-Zhi Wu, Feng-Shuang Yi, Kan Zhai, Huan-Zhong Shi
Diagnostic accuracy of human epididymis secretory protein 4 for lung cancer: a systematic review and meta-analysis
Li Yan, Zhi-De Hu
Thoracoscopic small pulmonary nodule detection using computed tomography-guided cutaneous marking and pleural marking
Atsushi Sekimura, Aika Funasaki, Shun Iwai, Nozomu Motono, Katsuo Usuda, Hidetaka Uramoto
Visceral pleural invasion in T1 tumors (≤3 cm), particularly T1a, in the eighth tumor-node-metastasis classification system for non-small cell lung cancer: a population-based study
Tao Zhang, Jia-Tao Zhang, Wen-Feng Li, Jun-Tao Lin, Si-Yang Liu, Hong-Hong Yan, Jin-Ji Yang, Xue-Ning Yang, Yi-Long Wu, Qiang Nie, Wen-Zhao Zhong
Comparison of the perioperative efficacy between single-port and two-port video-assisted thoracoscopic surgery anatomical lung resection for non-small cell lung cancer: a systematic review and meta-analysis
Wenlong Yang, Guozhong Zhang, Shu Pan, Zhihao Wang, Jianfeng Li, Weidong Ren, Hongcan Shi
Delayed traumatic diaphragmatic rupture: diagnosis and surgical treatment
Luo Zhao, Zhijun Han, Hongsheng Liu, Zhiyong Zhang, Shanqing Li
Multiportal subxiphoid thoracoscopic major pulmonary resections
Karel Pfeuty, Bernard Lenot
The safety and feasibility of thoracoscopic uncommon pulmonary segmentectomy
Hitoshi Igai, Mitsuhiro Kamiyoshihara, Ryohei Yoshikawa, Fumi Osawa, Tomohiro Yazawa
A quality assessment of evidence-based guidelines for the prevention and management of ventilator-associated pneumonia: a systematic review
Kairui Wan, Hengrui Liang, Guolin Yan, Bangyu Zou, Chuxin Huang, Mei Jiang
The characteristics of coronary-pulmonary artery fistulas and the effectivity of trans-catheter closure: a single center experience
Xin Liu, Lei Zhang, Zhiyong Qi, Mengkang Fan, Junbo Ge
S-1 salvage chemotherapy for stage IV thymic carcinoma: a study of 44 cases
Chang-Lu Wang, Lan-Ting Gao, Chang-Xing Lv
A prospective comparison of growth patterns with radiomorphology in 232 lung metastases—basis for patient tailored resection planning?
Nomair Issa, Elias Arfanis, Thomas Hager, Clemens Aigner, Sarah Dietz-Terjung, Dirk Theegarten, Hilmar Kühl, Stefan Welter
Effectiveness of intraoperative administration of intermittent pneumatic compression in preventing deep vein thrombosis in lung cancer patients undergoing video-assisted thoracoscopic surgery lobectomy
Xiaojun Wang, Saiqi Song, Ruijie Ni, Min Lu, Yanjun Mao
Video-assisted thoracoscopic surgery for invasive pulmonary fungal infection in haematology patients
Han Ma, Jun Wang, Xiao Ma, Shiying Zheng, Haitao Ma, Jinfeng Ge
From pullout-techniques to modular elastic stable chest repair: the evolution of an open technique in the correction of pectus excavatum
Stefan Schulz-Drost, Julia Syed, Anna-Maria Luber, Roman T. Carbon, Manuel Besendörfer
Single-center experience of extracorporeal membrane oxygenation mainly anticoagulated with nafamostat mesilate
Woosik Han, Jin San Bok, Hyun Jin Cho, Jae Hyeon Yu, Myung Hoon Na, Shinkwang Kang, Min-Woong Kang
A nomogram prediction model for recurrent laryngeal nerve lymph node metastasis in thoracic oesophageal squamous cell carcinoma
Yu Liu, Zhi-Qiang Zou, Juan Xiao, Mei Zhang, Lei Yuan, Xiao-Gang Zhao
Economic variations in patterns of care and outcomes of patients receiving invasive mechanical ventilation in China: a national cross-sectional survey
Ling Liu, Zhiwei Gao, Yi Yang, Maoqin Li, Xinwei Mu, Xiaochun Ma, Guicheng Li, Wen Sun, Xue Wang, Qin Gu, Ruiqiang Zheng, Hongsheng Zhao, Jianfeng Xie, Haibo Qiu
Expression levels of paraoxonase-1 in aortic valve tissue are associated with the progression of calcific aortic valve stenosis
Jian Song, Qiang Zheng, Xiaochun Ma, Qian Zhang, Zhenqiang Xu, Chengwei Zou, Zhengjun Wang
First-line immune checkpoint inhibitors for advanced non-small cell lung cancer with wild-type epidermal growth factor receptor (EGFR) or anaplastic lymphoma kinase (ALK): a systematic review and network meta-analysis
Tingting Liu, Silu Ding, Jun Dang, Hui Wang, Jun Chen, Guang Li
Clinical utility of robot-assisted transthoracic esophagectomy in advanced esophageal cancer after neoadjuvant chemoradiation therapy
Jae Kwang Yun, In-Seob Lee, Chung-Sik Gong, Bum Soo Kim, Hyeong Ryul Kim, Dong Kwan Kim, Seung-Il Park, Yong-Hee Kim
Interobserver size measurement variability in part-solid lung adenocarcinoma using pre-operative computed tomography
Kazutoshi Hamanaka, Hiroki Takayama, Tsutomu Koyama, Shunichiro Matsuoka, Tetsu Takeda, Hiroyuki Agatsuma, Kyoko Yamada, Akira Hyogotani, Satoshi Kawakami, Ken-ichi Ito
Video-assisted thoracoscopic surgery for ectopic mediastinal parathyroid tumor: subxiphoid and lateral thoracic approach
Hiromitsu Nagano, Takashi Suda, Hisato Ishizawa, Takahiro Negi, Hiroshi Kawai, Toru Kawakami, Daisuke Tochii, Sachiko Tochii, Yasushi Hoshikawa
The technique of intraoperative axillary artery cannulation for extracorporeal membrane oxygenation in lung transplantation
Chao Yang, Guilin Peng, Xin Xu, Bing Wei, Hanyu Yang, Jianxing He
Surgical technique modifies the postoperative atrioventricular block rate in sutureless prostheses
Miguel González Barbeito, Francisco Estévez-Cid, Patricia Pardo Martínez, Carlos Velasco García de Sierra, Carmen Iglesias Gil, Cristina Quiñones Laguillo, José Joaquín Cuenca Castillo
Validation of the 8th edition of the TNM staging system in 3,950 patients with surgically resected non-small cell lung cancer
Jae Kwang Yun, Geun Dong Lee, Hyeong Ryul Kim, Yong-Hee Kim, Dong Kwan Kim, Seung-Il Park, Sehoon Choi
Efficacy and safety of crizotinib in patients with ROS1 rearranged non-small cell lung cancer: a retrospective analysis
Ken Masuda, Yutaka Fujiwara, Yuki Shinno, Takaaki Mizuno, Jun Sato, Ryo Morita, Yuji Matsumoto, Shuji Murakami, Yasushi Goto, Shintaro Kanda, Hidehito Horinouchi, Noboru Yamamoto, Yuichiro Ohe
Consistency of radiologists in identifying pulmonary nodules based on low-dose computed tomography
Shuai Ming, Wei Yang, Si-Jia Cui, Shuai Huang, Xiang-Yang Gong
Clinical importance of Bcl-2-like 11 deletion polymorphism in idiopathic pulmonary fibrosis
Kazutoshi Isobe, Takuma Issiki, Susumu Sakamoto, Go Sano, Yujiro Takai, Naobumi Tochigi, Sakae Homma
Nomogram predicting cancer-specific mortality in patients with esophageal adenocarcinoma: a competing risk analysis
Xi-Xi Wu, Ren-Pin Chen, Rui-Cong Chen, Hong-Peng Gong, Bin-Feng Wang, Ya-Ling Li, Xin-Ran Lin, Zhi-Ming Huang
Comprehensive analysis of EGFR T790M detection by ddPCR and ARMS-PCR and the effect of mutant abundance on the efficacy of osimertinib in NSCLC patients
Yue Li, Yuxia Xu, Xiaoyan Wu, Caiyun He, Qing Liu, Fang Wang
miR-30b-5p acts as a tumor suppressor microRNA in esophageal squamous cell carcinoma
Jianfeng Xu, Haiyan Lv, Bo Zhang, Feng Xu, Hongyu Zhu, Baofu Chen, Chengchu Zhu, Jianfei Shen
Magnolol inhibits growth and induces apoptosis in esophagus cancer KYSE-150 cell lines via the MAP kinase pathway
Yu Chen, Kenan Huang, Xinyu Ding, Hua Tang, Zhifei Xu
Intermediate-term outcomes after aortic valve replacement with a novel RESILIATM tissue bioprosthesis
Krzysztof Bartus, Radoslaw Litwinowicz, Agata Bilewska, Maciej Stapor, Maciej Bochenek, Jacek Rozanski, Jerzy Sadowski, Grzegorz Filip, Boguslaw Kapelak, Mariusz Kusmierczyk
Comparing the benefits of postoperative adjuvant chemotherapy vs. observation for stage IB non-small cell lung cancer: a meta-analysis
Ranhua Li, Guixue Yang, Ye Tian, Dali Tian
Role of miRNA-181a-2-3p in cadmium-induced inflammatory responses of human bronchial epithelial cells
Jeeyoung Kim, Dong Yeop Kim, Hye-Ryeon Heo, Sun Shim Choi, Seok-Ho Hong, Woo Jin Kim
Acute effects of air pollutants on daily mortality and hospitalizations due to cardiovascular and respiratory diseases
Chaicharn Pothirat, Warawut Chaiwong, Chalerm Liwsrisakun, Chaiwat Bumroongkit, Athavudh Deesomchok, Theerakorn Theerakittikul, Atikun Limsukon, Pattraporn Tajarernmuang, Nittaya Phetsuk
A new technology for reducing anastomotic fistula in the neck after esophageal cancer surgery
Ya-Nan Song, Yu Qi, Chun-Yang Zhang, Yin-Liang Sheng, Kai Wu, Sen-Lin Zhu, Lu Han, Ting-ting Shan, Guan-Chao Ye, Qing-Yi Zhang, Yan-Li Chen, Jin-Wei Chen, Ya-Fei Liu, Lu-Bing Gao, Yang Yang, Zhan-Feng He, Deng-Yan Zhu, Dong-Lei Liu, Feng-Biao Wen, Tian-Liang Zheng, Ji-Lun Li, Song Zhao
Etiologies associated with chronic cough and its clinical characteristics in school-age children
Xingmei Yu, Lingjun Kong, Wujun Jiang, Yinfang Dai, Yuqing Wang, Li Huang, Wei Luo, Kefang Lai, Chuangli Hao
Retrospective study of efficacy of adjuvant chemotherapy using tegafur-uracil in patients with non-small cell lung cancer with primary tumor size of 4.1–5.0 cm
Hiroyuki Adachi, Teppei Nishii, Taketsugu Yamamoto, Takuya Nagashima, Yoshihiro Ishikawa, Kohei Ando, Tekkan Woo, Takamitsu Maehara, Haruhiko Nakayama, Munetaka Masuda
Long-term oncological outcome after thoracoscopic lobectomy for non-small cell lung cancer patients
Masayuki Nakao, Junji Ichinose, Yosuke Matsuura, Ken Nakagawa, Sakae Okumura, Mingyon Mun

iMDT Corner

Cryobiopsy in the diagnosis of idiopathic pulmonary hemosiderosis: a case report
Aleksander Kania, Magdalena Misiaszek, Martina Vašáková, Artur Szlubowski, Antonio Bugalho, Juliusz Pankowski, Małgorzata Szołkowska, Anja C. Roden, Natalia Celejewska-Wójcik, Paweł Nastałek, Maciej Gnass, Krzysztof Sładek

Editorial of GARD Section

The impact of conflict on asthma
Yousser Mohammad, Grace Brough

Review Article of Interventional Pulmonology Corner

Pleuroscopy or video-assisted thoracoscopic surgery for exudative pleural effusion: a comparative overview
Muhammad Sajawal Ali, Richard W. Light, Fabien Maldonado


Erratum to simple pre-procedure risk stratification tool for contrast-induced nephropathy
Zhonghan Ni, Yan Liang, Nianjin Xie, Jin Liu, Guoli Sun, Shiqun Chen, Jianfeng Ye, Yibo He, Wei Guo, Ning Tan, Jiyan Chen, Yong Liu, Zhujun Chen, Shouhong Wang

Review Article

Molecular biology of lung cancer
Wendy A. Cooper, David C. L. Lam, Sandra A. O’Toole, John D. Minna
Nontuberculous mycobacterial pulmonary infections
Margaret M. Johnson, John A. Odell
Treatment of advanced non small cell lung cancer
Maria Anna Bareschino, Clorinda Schettino, Antonio Rossi, Paolo Maione, Paola Claudia Sacco, Rosario Zeppa, Cesare Gridelli
Chemotherapy advances in small-cell lung cancer
Bryan A. Chan, Jermaine I. G. Coward
Electromagnetic navigation bronchoscopy: A descriptive analysis
Steven Leong, Hong Ju, Henry Marshall, Rayleen Bowman, Ian Yang, Ann-Maree Ree, Cathy Saxon, Kwun M Fong
Targeted therapy in lung cancer: IPASS and beyond, keeping abreast of the explosion of targeted therapies for lung cancer
Peter Savas, Brett Hughes, Benjamin Solomon
Stereotactic ablative radiotherapy for stage I NSCLC: Recent advances and controversies
Suresh Senan, David A. Palma, Frank J. Lagerwaard
The anticipation and management of air leaks and residual spaces post lung resection
Michael Rolf Mueller, Beatrice A. Marzluf
Exploiting sensitization windows of opportunity in hyper and hypo-fractionated radiation therapy
Anish Prasanna, Mansoor M. Ahmed, Mohammed Mohiuddin, C. Norman Coleman
Ultrasound techniques in the evaluation of the mediastinum, part 2: mediastinal lymph node anatomy and diagnostic reach of ultrasound techniques, clinical work up of neoplastic and inflammatory mediastinal lymphadenopathy using ultrasound techniques and how to learn mediastinal endosonography
Christian Jenssen, Jouke Tabe Annema, Paul Clementsen, Xin-Wu Cui, Mathias Maximilian Borst, Christoph Frank Dietrich
Revisiting signs, strengths and weaknesses of Standard Chest Radiography in patients of Acute Dyspnea in the Emergency Department
Luciano Cardinale, Giovanni Volpicelli, Alessandro Lamorte, Jessica Martino, Andrea veltri
The continuing role of chemotherapy for advanced non-small cell lung cancer in the targeted therapy era
Zarnie Lwin, Jonathan W. Riess, David Gandara
MicroRNAs in mesothelioma: from tumour suppressors and biomarkers to therapeutic targets
Glen Reid
Pleural controversies: image guided biopsy vs. thoracoscopy for undiagnosed pleural effusions?
Giles Dixon, Duneesha de Fonseka, Nick Maskell
Preservation solutions for cardiac and pulmonary donor grafts: a review of the current literature
Nicholas Latchana, Joshua R. Peck, Bryan Whitson, Sylvester M. Black
Active-specific immunotherapy for non-small cell lung cancer
Hauke Winter, Natasja K. van den Engel, Margareta Rusan, Nina Schupp, Christian H. Poehlein, Hong Ming Hu, Rudolf A. Hatz, Walter J. Urba, Karl Walter Jauch, Bernard A. Fox, Dominik Rüttinger
Advanced imaging in COPD: insights into pulmonary pathophysiology
Stephen Milne, Gregory G. King
Advances in lung adenocarcinoma classification: a summary of the new international multidisciplinary classification system (IASLC/ATS/ERS)
Elizabeth R. Tang, Andrew M. Schreiner, Bradley B. Pua
Diagnosis and early detection of COPD using spirometry
David P. Johns, Julia A.E. Walters, E. Haydn Walters
Improving radiotherapy planning, delivery accuracy, and normal tissue sparing using cutting edge technologies
Carri K. Glide-Hurst, Indrin J. Chetty
Pediatric lung transplantation: indications and outcomes
Stephen Kirkby, Don Hayes Jr
Staging lymph node metastases from lung cancer in the mediastinum
Mario D. Terán, Malcolm V. Brock
JTD special edition ‘Hot Topics in COPD’—The microbiome in COPD
Daniel C. Chambers, Shaan L. Gellatly, Philip Hugenholtz, Philip M. Hansbro
Lung donor selection criteria
John Chaney, Yoshikazu Suzuki, Edward Cantu III, Victor van Berkel
Molecular markers to predict clinical outcome and radiation induced toxicity in lung cancer
Joshua D. Palmer, Nicholas G. Zaorsky, Matthew Witek, Bo Lu
Lung cancer screening: identifying the high risk cohort
Michael W. Marcus, Olaide Y. Raji, John K. Field
Pleural controversies: indwelling pleural catheter vs. pleurodesis for malignant pleural effusions
Marc Fortin, Alain Tremblay
New techniques for assessing response after hypofractionated radiotherapy for lung cancer
Sarah A. Mattonen, Kitty Huang, Aaron D. Ward, Suresh Senan, David A. Palma
Supportive and palliative care for lung cancer patients
Patsy Yates, Penelope Schofield, Isabella Zhao, David Currow

Original Article

Nonintubated thoracoscopic lung resection: a 3-year experience with 285 cases in a single institution
Ke-Cheng Chen, Ya-Jung Cheng, Ming-Hui Hung, Yu-Ding Tseng, Jin-Shing Chen
Delays in the diagnosis of lung cancer
Peter M Ellis, Rachel Vandermeer
The diagnostic utility of endobronchial ultrasonography with a guide sheath and tomosynthesis images for ground glass opacity pulmonary lesions
Takehiro Izumo, Shinji Sasada, Christine Chavez, Takaaki Tsuchida
Hydration with magnesium and mannitol without furosemide prevents the nephrotoxicity induced by cisplatin and pemetrexed in patients with advanced non-small cell lung cancer
Keiko Muraki, Ryo Koyama, Yuichiro Honma, Shigehiro Yagishita, Takehito Shukuya, Rina Ohashi, Fumiyuki Takahashi, Kenji Kido, Shin-ichiro Iwakami, Shinichi Sasaki, Akihiko Iwase, Kazuhisa Takahashi
Local control rates with five-fraction stereotactic body radiotherapy for oligometastatic cancer to the lung
Deepinder Singh, Yuhchyau Chen, Mary Z. Hare, Kenneth Y. Usuki, Hong Zhang, Thomas Lundquist, Neil Joyce, Michael C. Schell, Michael T. Milano
Theoretical models of carcinogenic particle deposition and clearance in children’s lungs
Robert Sturm
A novel paradigm in the treatment of oligometastatic non-small cell lung cancer
Salma K Jabbour, Parima Daroui, Dirk Moore, Edward Licitra, Molly Gabel, Joseph Aisner
Radiotherapy for a second primary lung cancer arising post-pneumonectomy: planning considerations and clinical outcomes
Sashendra Senthi, Cornelis J. A. Haasbeek, Frank J. Lagerwaard, Wilko F. Verbakel, Patricia F. de Haan, Ben J. Slotman, Suresh Senan
Impact of metformin use on survival in locally-advanced, inoperable non-small cell lung cancer treated with definitive chemoradiation
Inaya Ahmed, Adam Ferro, Alan Cohler, John Langenfeld, Sujani G. Surakanti, Joseph Aisner, Wei Zou, Bruce G. Haffty, Salma K. Jabbour
Utility of EBUS-TBNA for diagnosis of mediastinal tuberculous lymphadenitis: a multicentre Australian experience
James Geake, Gary Hammerschlag, Phan Nguyen, Peter Wallbridge, Grant A. Jenkin, Tony M. Korman, Barton Jennings, Douglas F. Johnson, Louis B. Irving, Michael Farmer, Daniel P. Steinfort
Comparative outcomes of squamous and non-squamous non-small cell lung cancer (NSCLC) patients in phase II studies of ASA404 (DMXAA) – retrospective analysis of pooled data
Mark J McKeage, Michael B Jameson, AS1404-201 Study Group Investigators
High prevalence of gene abnormalities in young patients with lung cancer
Osamu Nagashima, Rina Ohashi, Yasuko Yoshioka, Ai Inagaki, Manabu Tajima, Yoshika Koinuma, Shin-ichiro Iwakami, Akihiko Iwase, Shinichi Sasaki, Shigeru Tominaga, Kazuhisa Takahashi
Home-based exercise: promising rehabilitation for symptom relief, improved functional status and quality of life for post-surgical lung cancer patients
Amy J. Hoffman, Ruth Ann Brintnall, Alexander von Eye, Lee W. Jones, Gordon Alderink, Lawrence H. Patzelt, Jean K. Brown
Thoracic malignant solitary fibrous tumors: A population-based study of survival
Michael T Milano, Deepinder P Singh, Hong Zhang
Differences in chemosensitivity between primary and paired metastatic lung cancer tissues: In vitro analysis based on the collagen gel droplet embedded culture drug test (CD-DST)
Masahiko Higashiyama, Jiro Okami, Jun Maeda, Toshiteru Tokunaga, Ayako Fujiwara, Ken Kodama, Fumio Imamura, Hisayuki Kobayashi
High-resolution CT findings of patients with pulmonary nocardiosis
Naoki Tsujimoto, Takeshi Saraya, Ken Kikuchi, Saori Takata, Yasuyuki Kurihara, Sayuki Hiraoka, Hiroshi Makino, Shota Yonetani, Koji Araki, Haruyuki Ishii, Hajime Takizawa, Hajime Goto
Signal stratification of autoantibody levels in serum samples and its application to the early detection of lung cancer
Graham F. Healey, Stephen Lam, Peter Boyle, Geoffrey Hamilton-Fairley, Laura J. Peek, John F. R. Robertson

Case Report

First report of a novel liquid nitrogen adjustable flow spray cryotherapy (SCT) device in the bronchoscopic treatment of disease of the central tracheo-bronchial airways
Robert Browning, Scott Parrish, Saiyad Sarkar, J. Francis Turner Jr
Severe amiodarone induced pulmonary toxicity
Nicholas Nacca, Castigliano M Bhamidipati, Luke S Yuhico, Sowmya Pinnamaneni, Tamas Szombathy


Guidelines for the diagnosis and treatment of malignant pleural mesothelioma
Nico van Zandwijk, Christopher Clarke, Douglas Henderson, A. William Musk, Kwun Fong, Anna Nowak, Robert Loeragan, Brian McCaughan, Michael Boyer, Malcolm Feigen, David Currow, Penelope Schofeild, Beth Ivimey Nick Pavlakis, Jocelyn McLean, Henry Marshall, Steven Leong, Victoria Keena, Andrew Penman

Research Highlight

Gene expression assays as prognostic and predictive markers in early stage non-small cell lung cancer
Tom Donnem, Roy M Bremnes, Lill-Tove Busund, Sigve Andersen, Francesco Pezzella

Short Communication

The sleep apnea cardiovascular endpoints (SAVE) trial: Rationale and start-up phase
R Doug McEvoy, Craig S Anderson, Nick A Antic, Baoyuan Chen, Quanying He, Emma Heeley, Shaoguang Huang, Yining Huang, Jiguang Wang, Nanshan Zhong

Circulating Tumor Cells

Detection methods of circulating tumor cells
Klaus Pantel, Catherine Alix-Panabières

Review Article

Atypical antibody responses to influenza
Dalton Hermans, Richard J. Webby, Sook-San Wong
What can individuals do to reduce personal health risks from air pollution?
Robert Laumbach, Qingyu Meng, Howard Kipen
The role of rotors in atrial fibrillation
David E. Krummen, Vijay Swarup, Sanjiv M. Narayan
Current outcomes of off-pump versus on-pump coronary artery bypass grafting: evidence from randomized controlled trials
Daniel Fudulu, Umberto Benedetto, Gustavo Guida Pecchinenda, Pierpaolo Chivasso, Vito Domenico Bruno, Filippo Rapetto, Alan Bryan, Gianni Davide Angelini
Staging lymph node metastases from lung cancer in the mediastinum
Mario D. Terán, Malcolm V. Brock
Improving radiotherapy planning, delivery accuracy, and normal tissue sparing using cutting edge technologies
Carri K. Glide-Hurst, Indrin J. Chetty
Esophageal cancer: staging system and guidelines for staging and treatment
Mark F. Berry
Implementing the new IASLC/ATS/ERS classification of lung adenocarcinomas: results from international and Chinese cohorts
Ming-Ching Lee, Kyuichi Kadota, Daniel Buitrago, David R. Jones, Prasad S. Adusumilli
Premature menopause in young breast cancer: effects on quality of life and treatment interventions
Shoshana M. Rosenberg, Ann H. Partridge
Strategies for the acquisition of transcriptional and epigenetic information in single cells
Guang Li, Elda Dzilic, Nick Flores, Alice Shieh, Sean M. Wu
The role of transforming growth factor (TGF)-β in the infarcted myocardium
Nikolaos G. Frangogiannis
Utility of cardiac magnetic resonance for evaluation of mitral regurgitation prior to mitral valve surgery
Neil K. Mehta, Jiwon Kim, Jonathan Y. Siden, Sara Rodriguez-Diego, Javid Alakbarli, Antonino Di Franco, Jonathan W. Weinsaft
Adjuvant, neoadjuvant, and definitive radiation therapy for malignant pleural mesothelioma
Gwendolyn Cramer, Charles B. Simone II, Theresa M. Busch, Keith A. Cengel

Original Article

Suppressive oligonucleotides inhibit inflammation in a murine model of mechanical ventilator induced lung injury
Julia Scheiermann, Dennis M. Klinman
Five-year update on the mouse model of orthotopic lung transplantation: Scientific uses, tricks of the trade, and tips for success
Xue Lin, Wenjun Li, Jiaming Lai, Mikio Okazaki, Seiichiro Sugimoto, Sumiharu Yamamoto, Xingan Wang, Andrew E. Gelman, Daniel Kreisel, Alexander Sasha Krupnick
A pooled analysis of advanced nonsquamous non-small cell lung cancer patients with stable treated brain metastases in two phase II trials receiving bevacizumab and pemetrexed as second-line therapy
Matthew A. Gubens, Jody C. Chuang, Wallace Akerley, Corey J. Langer, Christelle Clément- Duchêne, Melanie San Pedro-Salcedo, A. Dimitrios Colevas, Konstantin Dragnev, Mark A. Socinski, Heather A. Wakelee
Pleurodesis: a comparison of two sclerosing agents for pleural effusions in Mozambique
Ivo Figueiredo, Anilsa Cossa, Anila Hassane, José Sousa, Joaquim Pondo, João Teixeira, Kevan Akrami, Susannah K. Graves, Atul Malhotra, Elizabete A. Nunes

Case Report

Intraoperative near-infrared imaging can identify subcentimeter colorectal cancer lung metastases during pulmonary metastasectomy
Andrew D. Newton, Jarrod D. Predina, Lydia G. Frenzel-Sulyok, Michael H. Shin, Yiqing Wang, Sunil Singhal
A novel strategy for cardiopulmonary support during lung transplantation
Ramiro Fernandez, Malcolm M. DeCamp, Ankit Bharat


Conservatism strikes back: later is better than earlier dialysis for acute kidney injury
Dana Bielopolski, Kamyar Kalantar-Zadeh
Sleep and critical illness: bridging the two pillars at the ATS 2016
Stuti J. Jaiswal, Atul Malhotra, Robert L. Owens
Temperature and duration targets during post-arrest care: choosing the right prescription for the right patient
John C. Greenwood, Abhishek Bhardwaj, Benjamin S. Abella
Examining the paradox of high high-density lipoprotein and elevated cardiovascular risk
Kavisha Singh, Anand Rohatgi
Mortality after red blood cell transfusions from previously pregnant donors: complexities in the interpretation of large data
Susan Kuldanek, Christopher C. Silliman
Optogenetic tools for cell biological applications
Abhirup Mukherjee, Nicole A. Repina, David V. Schaffer, Ravi S. Kane
Editorial on “Transcription factor SPZ1 promotes TWIST-mediated epithelial—mesenchymal transition and oncogenesis in human liver cancer”
Dan J. Raz
Editorial on “Can CT-PET and endoscopic assessment post-neoadjuvant chemoradiotherapy predict residual disease in esophageal cancer”
Chia-Ju Liu, Wei Lu
The hemodynamic impact of acute nasal continuous positive airway pressure treatment in hypertrophic cardiomyopathy: is it safe?
Bo Xu, Reena Mehra
Tumor spread through air space (STAS) is an important predictor of clinical outcome in stage IA lung adenocarcinoma
Hui-Zi Chen, Erin M. Bertino, Kai He
Antiviral prophylaxis of cytomegalovirus reactivation in immune competent patients—the jury remains out
Sara A. Mansfield, Charles H. Cook
Allosterically targeting EGFR drug-resistance gatekeeper mutations
Nicholas Spellmon, Chunying Li, Zhe Yang
Imaging homeostatic sleep pressure and circadian rhythm in the human brain
Zhuo Fang, Hengyi Rao
Tumor mutational burden (TMB) as a biomarker of response to immunotherapy in small cell lung cancer
Yanis Boumber

Letter to the Editor

Response to “VATS vs. thoracotomy regarding postoperative chronic pain”
Emine Ozgur Bayman, Kalpaj R. Parekh, John Keech, Timothy J. Brennan
The role of a decision analysis in treatment of T2N0 esophageal cancer
Tara R. Semenkovich, Bryan F. Meyers, Benjamin D. Kozower, Varun Puri

Review Article on Left Ventricular Assist Devices

Left ventricular assist device driveline infections: recent advances and future goals
Anne-Marie Leuck

Short Communication of Interventional Pulmonology Corner

Endobronchial ultrasound—guidance for interstitial photodynamic therapy of locally advanced lung cancer—a new interventional concept
Kassem Harris, Emily Oakley, David Bellnier, Gal Shafirstein

Below are the latest Journal of Thoracic Disease articles published online ahead of print publication.

Review Article

Original Article

Brief Report

Surgical Technique


Surgical Technique

Editorial Commentary