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Sleep complaints and sleep breathing disorders in upper and lower obstructive lung diseases

Continuous positive airway pressure (CPAP) treatment of sleep apnea needs to be tailored after... More >>

The unity of respiratory patient advocacy

Dr. Baiardini and her colleagues have come to several important conclusions in their clinical... More >>

Post hoc ergo propter hoc

The Greeks and Romans recognized this fallacy in argument thousands of years ago. This faulty... More >>

Statistics Corner Column more

Guidelines for standardizing and increasing the transparency in the reporting of biomedical research

Guidelines for standardizing and increasing the transparency in the reporting of biomedical research More >>

How to design a randomized clinical trial: tips and tricks for conduct a successful study in thoracic disease domain

How to design a randomized clinical trial: tips and tricks for conduct a successful study in... More >>

How to describe univariate data

How to describe univariate data More >>

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Editorial

What are diagnostic implications and limitations of assessing D-dimer and fibrin degradation products levels in the management of patients with acute aortic dissection?
Koichi Akutsu
The Sleep Apnea Cardiovascular Endpoints (SAVE) study: implications for health services and sleep research in China and elsewhere
Zhi-Hui Qiu, Yuan-Ming Luo, R. Doug McEvoy
Antiviral prophylaxis of cytomegalovirus reactivation in immune competent patients—the jury remains out
Sara A. Mansfield, Charles H. Cook
Noninvasive ventilation during acute respiratory distress syndrome in patients with cancer—what really matters
Gunther Hempel, David Petroff, Hermann Wrigge
Cigarette smoke-induced autophagy: a deadly association?
Nicolas Pallet
Post-operative high sensitivity troponin T (hsTnT): toward an extending use for diagnosis and management of myocardial injury after noncardiac surgery?
Xavier Chapalain, Olivier Huet
Role of consolidative stereotactic ablative radiotherapy in patients with oligometastatic non-small cell lung cancer
Umberto Ricardi, Niccolò Giaj Levra, Serena Badellino, Filippo Alongi
‘Lung-protective’ ventilation in acute respiratory distress syndrome: still a challenge?
Flavia Julie do Amaral Pfeilsticker, Ary Serpa Neto
The J-ALEX trial—is frontline alectinib a new standard of care?
Jeffrey Zweig,, Heather A. Wakelee
Hippo pathway in lung development
Yuyuan Dai, David Jablons, Liang You
The expanding role of tranexamic acid in the management of obstetric hemorrhage
John T. Sullivan
Do the blood pressure changes in association with continuous positive airway pressure compliance play an important role to improve cardiovascular outcomes?
Azusa Murata, Takatoshi Kasai
Preventing ventilator-induced lung injury—what does the evidence say?
Sandra Hoegl, Bernhard Zwissler
Heart-resident macrophages: are they involved in the rhythm of every beat?
Emanuel Harari, Liang Guo, Samantha L. Smith, Ryan E. Braumann, Renu Virmani, Aloke V. Finn
Human factors and human nature in cardiothoracic surgery
Michael D. Bolanos, Joseph B. Zwischenberger
Occult pN2 disease in lung cancer patients: a wide range of diseases endangering the long term prognosis
Marc Riquet, Ciprian Pricopi, Giuseppe Mangiameli, Alex Arame, Alain Badia, Françoise Le Pimpec Barthes
Mediastinal lymph node resection in stage IA non-small cell lung cancer with small nodule: is it mandatory?
Dong Kwan Kim
Inflammation, phagocytosis and cancer: another step in the CD47 act
Maria A. Smolle, Martin Pichler
Tumor spread through air space (STAS) is an important predictor of clinical outcome in stage IA lung adenocarcinoma
Hui-Zi Chen, Erin M. Bertino, Kai He
Four percent matters
Waël C. Hanna
Intensive alveolar recruitment strategy in the post-cardiac surgery setting: one PEEP level may not fit all
Laurent Bitker, Jean-Christophe Richard
First generation bioresorbable vascular scaffolds: do they hold the promise?
Islam Y. Elgendy, Ahmed N. Mahmoud, R. David Anderson
Bioresorbable scaffolds versus metallic stents in routine PCI: the plot thickens
Athanasios Katsikis, Patrick W. Serruys
The use of 3D printing in cardiac surgery
Chin Siang Ong, Narutoshi Hibino
Adverse events with bioresorbable vascular scaffolds in routine percutaneous coronary interventions: “coup de théâtre” or unfinished play?
Salvatore Cassese, Oliver Husser, Adnan Kastrati
Evacetrapib and cardiovascular outcomes: reasons for lack of efficacy
Theodosios D. Filippatos, Moses S. Elisaf
A few pills twice a day keep ALK-positive non-small-cell lung cancer at bay
Lorenza Landi, Federico Cappuzzo
WWC3: the bridge linking Hippo and Wnt pathways in lung cancer
Chunlin Ou, Xiayu Li, Guiyuan Li, Jian Ma
Robotic segmentectomy: far beyond choice
Suat Erus, Serhan Tanju
Editorial for robotic left lower lobectomy
Michael D. Zervos
Technical aspects of video-assisted and robotic-assisted thoracoscopic segmentectomy
Jon A. Lutz, Gregor J. Kocher
Robotic-assisted left upper lobectomy: facing the challenge head-on
Simon R. Turner, Daniela Molena
Robotic assisted right middle lobectomy
Waël C. Hanna
Is robotic surgery for NSCLC innovative enough?
Marcello Migliore
Robotic esophagectomy: a better way or just another way?
Jacob A. Klapper, Matthew G. Hartwig
Reduction of cardiovascular risk in subjects with high lipoprotein (a) levels
Giulia Malaguarnera, Saverio Latteri, Vito Emanuele Catania, Michele Malaguarnera

Evidenced-Based Clinical Problem Solving Article

The role of video-assisted thoracoscopic surgery for management of symptomatic pleural effusion after coronary artery bypass surgery: a best evidence topic report
Alfonso Fiorelli, Francesco Caronia, Aldo Prencipe, Mario Santini, Brendon Stiles

Original Article

The value of delayed phase enhanced imaging in malignant pleural mesothelioma
Akash M. Patel, Ian Berger, E. Paul Wileyto, Urooj Khalid, Drew A. Torigian, Arun C. Nachiappan, Eduardo M. Barbosa Jr, Warren B. Gefter, Maya Galperin-Aizenberg, Narainder K. Gupta, Charles B. Simone II, Andrew R. Haas, Evan W. Alley, Sunil Singhal, Keith A. Cengel, Sharyn I. Katz
Optimal cut-off value and clinical usefulness of the Adherence Starts with Knowledge-12 in patients with asthma taking inhaled corticosteroids
Masaya Takemura, Masayuki Nishio, Kensuke Fukumitsu, Norihisa Takeda, Hiroya Ichikawa, Takamitsu Asano, Hiroki Tomita, Yoshihiro Kanemitsu, Kosho Yoshikawa, Akio Niimi
Dynamic expression of transformating growth factor-β1 and caveolin-1 in the lung of Bleomycin-induced interstitial lung disease
Yida Xing, Li Wang, Hongjiang Wang, Xiaodan Kong, Libin Zhan
Multimodality treatment of stage II thymic tumours
Carolina Carillo, Daniele Diso, Sara Mantovani, Ylenia Pecoraro, Tiziano De Giacomo, Anna Maria Ciccone, Camilla Poggi, Flavia Longo, Raffaele Cassese, Vincenzo Tombolini, Erino Angelo Rendina, Federico Venuta, Marco Anile
The value of cell block based on fine needle aspiration for lung cancer diagnosis
Zhengwei Dong, Hui Li, Jun Zhou, Wei Zhang, Chunyan Wu
Body surface area: a novel predictor for conversion to thoracotomy in patients undergoing video-assisted thoracoscopic lung cancer lobectomy
Shuang-Jiang Li, Kun Zhou, Cheng Shen, Peng-Fei Li, Yan-Ming Wu, Zhi-Qiang Wang, Guo-Wei Che
The detectability of the pretreatment EGFR T790M mutations in lung adenocarcinoma using CAST-PCR and digital PCR
Tsutomu Tatematsu, Katsuhiro Okuda, Ayumi Suzuki, Risa Oda, Tadashi Sakane, Osamu Kawano, Hiroshi Haneda, Satoru Moriyama, Hidefumi Sasaki, Ryoichi Nakanishi
Effects of preemptive cerebrospinal fluid drainage on spinal cord protection during thoracic endovascular aortic repair
Seungjun Song, Suk-Won Song, Tae Hoon Kim, Kwang-Hun Lee, Kyung-Jong Yoo
Quantitative computed tomography to predict postoperative FEV1 after lung cancer surgery
Alex Fourdrain, Florence De Dominicis, Sophie Lafitte, Jules Iquille, Flavien Prevot, Emmanuel Lorne, Julien Monconduit, Patrick Bagan, Pascal Berna
Does lung cancer surgery cause circulating tumor cells?—A multicenter, prospective study
Noriyuki Matsutani, Noriyoshi Sawabata, Masafumi Yamaguchi, Tetsukan Woo, Yujin Kudo, Akikazu Kawase, Satoshi Shiono, Hisae Iinuma, Shigeki Morita, Masafumi Kawamura
Predictors of conversion to thoracotomy during video-assisted thoracoscopic surgery lobectomy in lung cancer: additional predictive value of FDG-PET/CT in a tuberculosis endemic region
Chun Geun Lim, Kyung Min Shin, Ji Seun Lim, Jae Kwang Lim, Hye Jung Kim, Won Hwa Kim, Seung Hyun Cho, Seung Ick Cha, Eung Bae Lee, Yangki Seock, Shin Young Jeong
Statins may be beneficial for patients with pulmonary hypertension secondary to lung diseases
Ming-Zhou Zhang, De-Hui Qian, Jian-Cheng Xu, Wei Yao, Ye Fan, Chang-Zheng Wang
LncRNA260-specific siRNA targeting IL28RA gene inhibit cardiomyocytes hypoxic/reoxygenation injury
Ge Gong, Xin-Xing Yang, Yanyan Li, Hong-Yu Geng, Zhi-Jian Yang, Lian-Sheng Wang, Hyun Jun Kim, Xin-Zheng Lu
Electro-physiological evidence of intercostal nerve injury after thoracotomy: an experimental study in a sheep model
Ruoyu Zhang, Kerstin Schwabe, Marcus Krüger, Axel Haverich, Joachim K. Krauss, Mesbah Alam
Chylothorax after pediatric cardiac surgery complicates short-term but not long-term outcomes—a propensity matched analysis
Nikoletta R. Czobor, György Roth, Zsolt Prodán, Daniel J. Lex, Erzsébet Sápi, László Ablonczy, Mihály Gergely, Edgar A. Székely, János Gál, Andrea Székely
The relationship between apnoea hypopnoea index and Gensini score in patients with acute myocardial infarction undergoing emergency primary percutaneous coronary intervention
Cai-Ping Zhu, Tao-Ping Li, Xiao Wang, Yu-Hua Zhao, Shi-Xi Zhou, Yan Fu, Yi-Wei Jiang, Xue- Ping Xiao
Simultaneous unilateral anterior thoracoscopy with transcervical thyroidectomy for the resection of large mediastinal thyroid goiter
Igor Brichkov, Shintaro Chiba, Victor Lagmay, Jason P. Shaw, Loren J. Harris, Michael Weiss
Does BioGlue contribute to anastomotic pseudoaneurysm after thoracic aortic surgery?
Wei-Guo Ma, Bulat A. Ziganshin, Chang-Fa Guo, Mohammad A. Zafar, Richard S. Sieller, Maryann Tranquilli, John A. Elefteriades
Expression of redox sensing factor Nrf2 in lung macrophages and type II pneumocytes as a prognostic factor in pneumothorax recurrence
Wen-Chin Chiu, Yen-Lung Lee, Shah-Hwa Chou, Yi-Chen Lee, Yu-Han Su, Yi-An Hou, Hung-Hsing Chiang, Hsin-Ling Yin, Stephen Chu-Sung Hu, Ming-Yii Huang, Chih-Jen Huang, Shyng-Shiou F. Yuan
Correlation between EGFR mutation status and the incidence of brain metastases in patients with non-small cell lung cancer
Lina Li, Shuimei Luo, Heng Lin, Haitao Yang, Huijuan Chen, Ziyuan Liao, Wanzun Lin, Weili Zheng, Xianhe Xie
Results of quantitative chest-CT in chronic pulmonary graftvs.- host disease (cGvHD) 3 years after allogeneic stem cell transplantation
Christopher Kloth, Wolfgang M. Thaiss, Jürgen Hetzel, Georg Bier, Stefan Wirths, Konstantin Nikolaou, Marius Horger
Pupillary abnormalities in non-selected critically ill patients: an observational study
Philippe Portran, Martin Cour, Romain Hernu, Sylvie de la Salle, Laurent Argaud
Cost and effectiveness of lung lobectomy by video-assisted thoracic surgery for lung cancer
Juan J. Mafé, Beatriz Planelles, Santos Asensio, Jorge Cerezal, María-del-Mar Inda, Javier Lacueva, Maria-Dolores Esteban, Luis Hernández, Concepción Martín, Benno Baschwitz, Ana M. Peiró
The predictive value of plasma cytokines on gastroesophageal anastomotic leakage at an early stage in patients undergoing esophagectomy
Jie-Qiong Song, Yi-Zhou He, Yuan Fang, Wei Wu, Ming Zhong
Standardized uptake value and radiological density attenuation as predictive and prognostic factors in patients with solitary pulmonary nodules: our experience on 1,592 patients
Duilio Divisi, Mirko Barone, Luca Bertolaccini, Gaetano Rocco, Piergiorgio Solli, Roberto Crisci, Italian VATS Group
A systematic and genome-wide correlation meta-analysis of PD-L1 expression and targetable NSCLC driver genes
Jin Li, Yaoqi Chen, Xiaoshun Shi, Xiaobing Le, Fenglan Feng, Jingyi Chen, Chengzhi Zhou, Yusong Chen, Shuai Wen, Haikang Zeng, Allen M. Chen, Yu Zhang
Assessment of pulmonary microstructural changes by hyperpolarized 129Xe diffusion-weighted imaging in an elastase-instilled rat model of emphysema
Ke Wang, Ting Pan, Hao Yang, Weiwei Ruan, Jianping Zhong, Guangyao Wu, Xin Zhou
Unique distribution of programmed death ligand 1 (PD-L1) expression in East Asian non-small cell lung cancer
Yunjian Pan, Difan Zheng, Yuan Li, Xu Cai, Zongli Zheng, Yan Jin, Haichuan Hu, Chao Cheng, Lei Shen, Jian Wang, Hongbin Ji, Yihua Sun, Xiaoyan Zhou, Haiquan Chen
Non-intubated single-incision video-assisted thoracic surgery: a two-center cohort of 188 patients
Man-Ling Wang, Carlos Galvez, Jin-Shing Chen, Jose Navarro-Martinez, Sergio Bolufer, Ming-Hui Hung, Hsao-Hsung Hsu, Ya-Jung Cheng

Original Article of Interventional Pulmonology Corner

Respiratory support with venovenous extracorporeal membrane oxygenation during stent placement for the palliation of critical airway obstruction: case series analysis
Jung-Hoon Park, Ji Hoon Shin, Kun Yung Kim, Ju Yong Lim, Pyeong Hwa Kim, Jiaywei Tsauo, Min Tae Kim, Ho-Young Song

Review Article

The technique of endoscopic airway tumor treatment
Simone Scarlata, Lello Fuso, Gabriele Lucantoni, Francesco Varone, Daniele Magnini, Raffaele Antonelli Incalzi, Gianni Galluccio
Management of pulmonary hypertension from left heart disease in candidates for orthotopic heart transplantation
Anna Koulova, Alan L. Gass, Saikrishna Patibandla, Chhaya Aggarwal Gupta, Wilbert S. Aronow, Gregg M. Lanier
Chronic lung allograft dysfunction phenotypes and treatment
Stijn E. Verleden, Robin Vos, Bart M. Vanaudenaerde, Geert M. Verleden
Donors after cardiocirculatory death and lung transplantation
Ilhan Inci
Lung allocation
Jens Gottlieb
Pediatric lung transplantation
Christian Benden
Outcomes after lung transplantation
Gabriel Thabut, Herve Mal

Study Protocol

Patient reported outcomes following video assisted thoracoscopic (VATS) resection or stereotactic ablative body radiotherapy (SABR) for treatment of non-small cell lung cancer: protocol for an observational pilot study (LiLAC)
Cecilia Pompili, Kevin N. Franks, Alessandro Brunelli, Yusuf S. Hussain, Patricia Holch, Matthew E. Callister, Jonathan M. Robson, Kostas Papagiannopoulos, Galina Velikova

Case Report

Benign superior vena cava syndrome with uncontrolled pleural effusion by calcified mediastinal lymphadenopathy: surgical management
Yoon Pyo Lee, Eun Mi Chun, Yoo Kyung Kim, Kwan Chang Kim
Catch me if you can—How to make the best use of pleural effusion
Lianjun Lin, Qian Han, Zhonghui Liu, Huiying Xu, Yanping Wu, Jixin Zhang, Xinmin Liu
Two cases of the bronchial carcinoid tumors successfully treated with the parenchymal-sparing bronchoplastic resections
Katarzyna Drożdż, Mariusz Chabowski, Angelika Chachaj, Paweł Gać, Małgorzata Szołkowska, Dariusz Janczak, Andrzej Szuba
Anterior bronchogenic mediastinal cyst as priority procedure for Robotic thoracic surgery
Umberto Caterino, Dario Amore, Marcellino Cicalese, Carlo Curcio
Two cases of pulmonary cysticercosis manifesting as pleural effusion: case report and literature review
Youfei Chen, Pingli Wang, Liren Ding
An unusually large paraesophageal hernia mimicking a Bochdalek hernia
Daneish Selvakumar, Karan Sian, Ajay J. Iyengar, Ross Mejia
Single lung retrieval from a donor supported by a left ventricular assist device
Keitaro Matsumoto, Naoya Yamasaki, Tomoshi Tsuchiya, Takuro Miyazaki, Ryotaro Kamohara, Go Hatachi, Kazuyoshi Tanigawa, Kiyoyuki Eishi, Takeshi Nagayasu
Surgical resection of a well-differentiated inflammatory liposarcoma of the middle mediastinum: a case report
Makoto Edagawa, Naoki Haratake, Shinichiro Shimamatsu, Ryo Toyozawa, Kaname Nosaki, Fumihiko Hirai, Masafumi Yamaguchi, Kenichi Taguchi, Koichiro Kaneko, Takashi Seto, Mitsuhiro Takenoyama, Yukito Ichinose
KRAS mutation-positive mucinous adenocarcinoma originating in the thymus
Ichiro Sakanoue, Hiroshi Hamakawa, Daichi Fujimoto, Yukihiro Imai, Kazuhiro Minami, Keisuke Tomii, Yutaka Takahashi
A hamartoma presenting as an intramural upper oesophageal tumour
Jari Räsänen, Ilkka Ilonen, Ari Ristimäki, Jarmo A. Salo, Antti A. Mäkitie
Primary pulmonary malignant fibrous histiocytoma: case report and literature review
Xiongfei Li, Renwang Liu, Tao Shi, Shangwen Dong, Fan Ren, Fan Yang, Dian Ren, Haiyang Fan, Sen Wei, Gang Chen, Jun Chen, Song Xu
A case of tuberculosis reactivation suspected of cancer progression during oral tyrosine kinase inhibitor treatment in a patient diagnosed as non-small cell lung cancer
Hwa Young Lee, Jin Woo Kim, Chang Dong Yeo
Single-stage surgery experience in a case of coarctation of the aorta with an arch aneurysm combined with severe coronary artery disease
Ran Mo, Yiguang Yan, Dongjin Wang
Successful removal of embolized chemoport catheter within the heart and pericardium: 3 case reports
Shin-Eui Yoon, Chang Hoon Lee
Misdiagnosis of anomalous pulmonary venous connections in a patient with lung cancer and a review of the literature
Nicola Tamburini, Irene Marchi, Matteo Bassi, Gabriele Anania, Francesco Quarantotto, Giorgio Cavallesco, Pio Maniscalco

Original Article

Catamenial pneumothorax: a rare entity? Report of 5 cases and review of the literature
Aikaterini N. Visouli, Kaid Darwiche, Andreas Mpakas, Paul Zarogoulidis, Antonios Papagiannis, Kosmas Tsakiridis, Nikolaos Machairiotis, Aikaterini Stylianaki, Nikolaos Katsikogiannis, Nicolaos Courcoutsakis, Konstantinos Zarogoulidis

Review Articles

A review of current and novel therapies for idiopathic pulmonary fibrosis
Rokhsara Rafii, Maya M. Juarez, Timothy E. Albertson, Andrew L. Chan
Superior sulcus (Pancoast) tumors: current evidence on diagnosis and radical treatment
Christophoros N. Foroulis, Paul Zarogoulidis, Kaid Darwiche, Nikolaos Katsikogiannis, Nikolaos Machairiotis, Ilias Karapantzos, Kosmas Tsakiridis, Haidong Huang, Konstantinos Zarogoulidis
Electromagnetic navigation bronchoscopy: A descriptive analysis
Steven Leong, Hong Ju, Henry Marshall, Rayleen Bowman, Ian Yang, Ann-Maree Ree, Cathy Saxon, Kwun M Fong
Epidemiology and prognosis of breast cancer in young women
Hussein A. Assi, Katia E. Khoury, Haifa Dbouk, Lana E. Khalil, Tarek H. Mouhieddine, Nagi S. El Saghir
Update in diagnosis and therapy of coexistent chronic obstructive pulmonary disease and chronic heart failure
Qiaojun Zeng, Shanping Jiang
Acute respiratory distress syndrome: new definition, current and future therapeutic options
Vito Fanelli, Aikaterini Vlachou, Shirin Ghannadian, Umberto Simonetti, Arthur S. Slutsky, Haibo Zhang
Revisiting signs, strengths and weaknesses of Standard Chest Radiography in patients of Acute Dyspnea in the Emergency Department
Luciano Cardinale, Giovanni Volpicelli, Alessandro Lamorte, Jessica Martino, Andrea veltri
Molecular biology of lung cancer
Wendy A. Cooper, David C. L. Lam, Sandra A. O’Toole, John D. Minna
Hormonal therapies in young breast cancer patients: when, what and for how long?
Alexandre Christinat, Simona Di Lascio, Olivia Pagani
The management of the advanced colorectal cancer: management of the pulmonary metastases
Charalambos Zisis, Kosmas Tsakiridis, Ioanna Kougioumtzi, Paul Zarogoulidis, Kaid Darwiche, Nikolaos Machairiotis, Bojan Zaric, Nikolaos Katsikogiannis, Georgios Kesisis, Aikaterini Stylianaki, Zhigang Li, Konstantinos Zarogoulidis
Pleural infection-current diagnosis and management
Andrew Rosenstengel, YC Gary Lee
COPD in India: Iceberg or volcano?
Arvind B. Bhome
Whole genome sequencing for lung cancer
Marissa Daniels, Felicia Goh, Casey M Wright, Krishna B Sriram, Vandana Relan, Belinda E Clarke, Edwina E Duhig, Rayleen V Bowman, Ian A Yang, Kwun M Fong

Original Articles

Establishment of an orthotopic lung cancer model in nude mice and its evaluation by spiral CT
Xiang Liu, Jun Liu, Yubao Guan, Huiling Li, Liyan Huang, Hailing Tang, Jianxing He
Hydration with magnesium and mannitol without furosemide prevents the nephrotoxicity induced by cisplatin and pemetrexed in patients with advanced non-small cell lung cancer
Keiko Muraki, Ryo Koyama, Yuichiro Honma, Shigehiro Yagishita, Takehito Shukuya, Rina Ohashi, Fumiyuki Takahashi, Kenji Kido, Shin-ichiro Iwakami, Shinichi Sasaki, Akihiko Iwase, Kazuhisa Takahashi

Perspectives

Surgical treatment of pulmonary tuberculosis: the phoenix of thoracic surgery?
Luca Bertolaccini, Andrea Viti, Giovanni Di Perri, Alberto Terzi

Art of Operative Techniques

Thoracoscopic anatomic pulmonary resection
Jianxing He, Xin Xu

Below are the latest Journal of Thoracic Disease articles published online ahead of print publication.

Editorial



Review Article


Original Article



Surgical Technique



Letter to the Editor



Review Article of Cough Section