Article Abstract

Perspectives on oligometastasis: challenges and opportunities

Authors: Jana Heitmann, Matthias Guckenberger


The concept that patients with only a few metastases from a malignant tumor can potentially be cured was developed in 1995 and termed “Oligo” (few) metastasis, describing an intermediate stage between localized and metastasized cancer (1). This concept is based on the hypothesis that there is a distinct stage of limited metastatic capability of the primary tumor (2): metastatic spread that behaves hierarchical in time and number opens the therapeutic window for a cure at an early, an “oligometastatic” stage.