Article Abstract

Circulating microRNAs as an emerging biomarker for acute aortic dissection diagnosis—comparing with prior biomarkers

Authors: Daigo Hiraya, Akira Sato, Kazutaka Aonuma


Acute aortic dissection (AAD) is a serious disease with a high mortality rate. The mortality rate for patients with type A AAD who do not get treatment is of 1–2% per hour during the first 24 hours and almost 50% of the patients die within a week (1). The highest mortality associated with AAD occurs in the first 48 hours after onset of symptoms.