Article Abstract

Causal role of rapid-eye-movement sleep on successful memory consolidation of fear extinction

Authors: Si-Zhi Ai, Xi-Jian Dai


The formation and consolidation of conditioned fear memory is a fundamental mammalian mechanism to adapt to the environment quickly. However, the persistent fear memories failure to extinction can be maladaptive and represent a core symptomatic dimension of fear related disorders such as post-traumatic stress disorder (PTSD) (1-3).