Advances in the use of motion management and image guidance in radiation therapy treatment for lung cancer

Jason K. Molitoris, Tejan Diwanji, James W. Snider III, Sina Mossahebi, Santanu Samanta, Shahed N. Badiyan, Charles B. Simone II, Pranshu Mohindra


The development of advanced radiation technologies, including intensity-modulated radiation therapy (IMRT), stereotactic body radiation therapy (SBRT) and proton therapy, has resulted in increasingly conformal radiation treatments. Recent evidence for the importance of minimizing dose to normal critical structures including the heart and lungs has led to incorporation of these advanced treatment modalities into radiation therapy (RT) for non-small cell lung cancer (NSCLC). While such technologies have allowed for improved dose delivery, implementation requires improved target accuracy with treatments, placing increasing importance on evaluating tumor motion at the time of planning and verifying tumor position at the time of treatment. In this review article, we describe issues and updates related both to motion management and image guidance in the treatment of NSCLC.