Terlipressin as a first choice in septic shock—not yet

Daniel Lima Rocha, Fabio Tanzillo Moreira, Ary Serpa Neto


Sepsis, a dysregulated host response to infection leading to organ dysfunction, and septic shock, a subset of patients with sepsis, cardiovascular collapse and cellular and metabolic dysfunction, are still major healthcare problems (1). Despite significant progresses in intensive care medicine, septic shock remains associated with high morbidity and mortality (1), and all efforts should be made to improve the outcomes of this group of patients. Patients presenting to the intensive care unit (ICU) with septic shock are frequently treated with vasopressors in addition to other supportive therapies (1,2).