The tidal volume fix and more…

Fabienne D. Simonis, Ary Serpa Neto, Marcus J. Schultz


In the past 30 years the medical literature has been enriched with numerous publications reporting on randomized clinical trials, meta-analysis and service reviews on invasive ventilation in critically ill patients (Figure 1). For many years the investigations on lung-protective ventilation focused on patients with acute respiratory distress syndrome (ARDS). Interest in the effects of lung-protective ventilation in patients without ARDS is rapidly increasing, however, resulting in a steep rise of the number of publications on lung-protection in patients without ARDS.