Randomized phase II trial reporting overall survival advantage by adding local consolidative therapy to systemic therapy for oligometastatic non-small cell lung cancer: another step forward on the long road of evidence-based medicine for oligometastatic disease

The term oligometastatic disease (OMD) has been coined in 1995 (1) for patients with a limited number of metastases that may be treated with a potentially curative intention. This intermediate cancer state between localized and metastatic disease was considered rare and both clinical and pre-clinical research was limited.