This series is the result of the work of different specialists from all around Italy and from Fudan University in Shanghai, who gathered in Milan on April 2019, to attend the Spring Meeting of Italian Society of Thoracic Surgery (SICT). The meeting discussed new evidences suggesting sublobar resection as the elective surgical treatment of early stage lung cancer.
Surgeons, pathologists, pneumologists, radiologists and all health professionals whose work focuses on lung cancer management analyzed the different aspects of sublobular resection in the management of early lung tumors .In recent years more efficient screening programs and modern computed tomography allowed a more frequent diagnosis of-centimetric and ground-glass like pulmonary lesions; as a consequence the treatment of these early lesions has emerged as a novel, exciting problem in thoracic surgery. Technical advances in minimally invasive surgery, both VATS and robotic, in electromagnetic navigation bronchoscopy and in stereotactic ablative radiotherapy and microwave ablation are quickly and dramatically changing the clinical treatment of early of lung cancer.
In the recent past, lung-sparing surgical resections were chosen by surgeons for patients with compromised lung function (1). Nowadays anatomical sublobar resections are the elective choice in patients with early stage non-small-cell lung cancer even in the presence of a poor cardiopulmonary reserve. Up-to date evidences stemming both from monocentric and non-randomized multicentric analyses support this approach; results on the oncological non-inferiority of lung-sparing anatomical resections are nevertheless still missing (2).
These novel research and clinical avenues were discussed at the SICT Spring Meeting; results of these extensive discussion are presented in the different articles of this series of the “Journal of Thoracic Disease” that we are honored to lead. Our thanks go to all those colleagues who agreed to contribute to this series.
Provenance and Peer Review: This article was commissioned by the editorial office, Journal of Thoracic Disease for the series “Early Stage Lung Cancer: Sublobar Resections are a Choice?”. The article did not undergo external peer review.
Conflicts of Interest: The authors have completed the ICMJE uniform disclosure form (available at http://dx.doi.org/10.21037/jtd-2020-eslc-11). The series was commissioned by the editorial office without any funding or sponsorship. IR, LR and MN served as the unpaid Guest Editors of the series.
Ethical Statement: All authors are accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.
- Howington JA, Blum MG, Chang AC, et al. Treatment of stage I and II non-small cell lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest 2013;143:e278S-e313S.
- Mendogni P, Tosi D, Rosso L, et al. VATS segmentectomy: an underused option? J Vis Surg 2017;3:136. [Crossref] [PubMed]