Transcatheter arterial embolization for intercostal arterial bleeding in a patient after chest tube insertion
Case Report

Transcatheter arterial embolization for intercostal arterial bleeding in a patient after chest tube insertion

Ren-Biao Chen1, Hong-Jie Hu1, Erik Matro2

1Department of Radiology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, China; 2School of Medicine, Zhejiang University, Hangzhou 310016, China

Correspondence to: Prof. Hong-Jie Hu, MD. Department of Radiology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, 3rd East Qingchun road, Hangzhou 310016, China. Email: hongjiehu@zju.edu.cn.

Abstract: Retrograde tube radiography is commonly used in cholangiography and pyelography. We present a case of massive chest tube bleeding 10 days after tube insertion with no noted contrast extravasation on contrast enhanced chest CT with active bleeding detected by retrograde radiography via the chest tube. Subsequent transcatheter arterial embolization (TAE) was successfully performed as a definitive treatment to stop active bleeding. We consider that retrograde tube radiography may be an alternative diagnostic method for patients with active bleeding from a drainage tube, helping to localize bleeding points and presenting TAE an attractive, minimally invasive and effective treatment modality for intercostal artery rupture.

Keywords: Hemorrhage; chest tube; angiography; embolization


Submitted Sep 19, 2014. Accepted for publication May 19, 2015.

doi: 10.3978/j.issn.2072-1439.2015.07.01


Introduction

Transcatheter arterial embolization (TAE) for treatment of thoracic disease is mainly applied in the setting of massive hemoptysis and progressively enlarging hemothorax. Progressive hemothorax is known to have a variety of etiologies; usually the sources of bleeding are the aorta and intercostals and pulmonary vessels (1). Contrast enhanced CT plays a significant role in localizing bleeding points (2). When contrast CT is non-diagnostic, exploratory thoracotomy, video-assisted thoracic surgery (VATS) exploration or angiography are usually considered. We present a case of iatrogenic massive bleeding, with retrograde radiography revealing bleeding points. The patient was successfully treated using TAE.


Case report

Our patient was a 54-year-old man who underwent emergent gastrorrhaphy due to gastric perforation, with a history of alcoholic cirrhosis for 15 years. A central venous puncture tube with side holes was inserted into the left 7th intercostal space for pleural effusion, and an average 500 mL of yellowish liquid was drained every day. On the 10th day after tube insertion, more than 1,000 mL of bloody fluid was suddenly drained. Fluid analysis revealed presence of whole blood, and the patient went into hypovolemic shock (emergent full blood count revealed a haemoglobin of 5.7 g/dL, platelet count of 28×109/L;and prothrombin time of 26.8 s, INR 2.54). The patient recovered from hemorrhagic shock after massive blood and fluid transfusion. Emergency chest CT scans with contrast revealed no exact point of contrast extravasation (Figure 1). However, bloody fluid was continually drained from the tube. Due to the unstable hemodynamic condition and coagulation disorders of the patient, VATS and exploratory laparotomy were deemed to not be tolerated well. Angiography was considered with continuous blood and fluid transfusion. Because no exact contrast extravasation was found on CT, retrograde angiography was performed via the chest tube and it revealed the left 7th intercostal artery (Figure 2). Subsequent transcatheter intercostal artery angiography through the right femoral artery revealed extravasation from the left 7th intercostal artery (Figure 3) and TAE was performed utilizing gelatin sponge particles and 2 coils. The extravasation of the contrast medium ceased (Figure 4) after embolization and the patient’s hemodynamic condition stabilized without massive fluid resuscitation being necessary.

Figure 1 Thoracic computed tomography with contrast medium shows the chest tube (arrow) under the rib and left hydrothorax without noted contrast extravasation.
Figure 2 Retrograde tube (black arrow) radiography revealed most of the contrast medium (arrow head) leaked to pleural space and the intercostal vessel can be seen (white arrow) at the same time.
Figure 3 Left 7th intercostal arteriography. The arrow shows contrast extravasation straight into the chest tube.
Figure 4 Intercostal arteriography shows no contrast extravasation after TAE with 2 coils (arrow).

Discussion

Chest tube insertion is a common procedure in the management of air and fluid collection within the pleural space. The procedure is considered safe but serious complications are encountered even in the hands of experienced personnel (3-5). Common complications include tube displacement, injury to chest wall vessels and to major cardiac and intrathoracic vascular structures (6). The rate of serious complication was reported to be around 2-3% (7). Among all the complications, injury to vessels leading to hemothorax or hematoma was the commonest, potentially leading to hypovolemic shock or sudden death (4). In our case, 10 days after chest tube insertion, the patient went into shock due to massive chest tube bleeding. Intercostal arteriography revealed contrast extravasation from the left 7th intercostal artery directly into the chest tube, and we assumed that tube displacement injured the intercostal artery and the side hole of the tube connected to the ruptured artery by chance. This resulted in little blood remaining in the pleural cavity and a lack of a hematoma in the thoracic wall. Contrast enhanced CT therefore could not detect active contrast extravasation.

When a patient is hemodynamically unstable, contrast-enhanced computed tomography (CECT) can detect the site of active bleeding in many cases, helping to direct angiographic embolization for haemostasis (8,9). In pulmonary injury associated with severe rib fracture, CECT is indicated when ≥200 mL/h of blood drains from the chest tube (2). However, when contrast CT is negative, exploratory thoracotomy and VATS should be considered in the absence of a coagulopathy. In our case, prothrombin time barely met the requirements of angiography and the patient’s hemodynamic condition remained unstable even with massive fluid and blood transfusion. Retrograde radiography was performed via the chest tube in order urgently locate the bleeding point, and we located the ruptured artery.

TAE is widely used to manage active bleeding in splenic, hepatic, and renal injury, as well as pelvic fractures in trauma patients (10). This modality is also an effective method of hemostasis that minimizes iatrogenic injury in trauma patients with hemothorax, which is much less invasive than a thoracotomy (2,11-14). Our patient was not a suitable candidate for surgery or VATS; TAE therefore became the most effective and minimally invasive method of choice.

In conclusion, retrograde tube radiography may be an alternative method for cases with the massive bleeding from drainage tubes, which can assist in localization of bleeding points.


Acknowledgements

None.


Footnote

Conflicts of Interest: The authors have no conflicts of interest to declare.


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Cite this article as: Chen RB, Hu HJ, Matro E. Transcatheter arterial embolization for intercostal arterial bleeding in a patient after chest tube insertion. J Thorac Dis 2015;7(7):E194-E197. doi: 10.3978/j.issn.2072-1439.2015.07.01