Vol 7, No 3 (March 30, 2015): Journal of Thoracic Disease


Anti-angiogenic therapy in advanced non-small cell lung carcinoma (NSCLC): is there a role in subsequent lines of therapy?
Abdulaziz Al Farsi, Peter M. Ellis
Epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer: a decade of progress and hopeful future
Kumar Rajagopalan, Ramaswamy Govindan
Clinical implications and future perspectives in testing non-small cell lung cancer (NSCLC) for anaplastic lymphoma kinase (ALK) gene rearrangements
Francesco Gelsomino, Giulio Rossi, Marcello Tiseo
Chemotherapy versus tyrosine kinase inhibitor in EGFR unselected population advanced non-small cell lung cancer still matter of debate?—An update incorporating the DELTA trial data
Marina C. Garassino, Massimo Broggini
Second-line treatment in EGFR-unselected patients: is it time to close one arm of this river’s DELTA?
Daniela Morales-Espinosa, Rafael Rosell
The challenge of using biomarkers and molecularly targeted drugs to improve cure rate in early stage non-small cell lung cancer
Nevin Murray
Individualizing adjuvant therapy for early stage non-small cell lung cancer: we see the destination, but we don’t yet know the route
Howard West
Accessing critical care big data: a step by step approach
Zhongheng Zhang

Original Article

Adjuvant chemotherapy after resection of N1 non-small cell lung cancer: differential impact of new evidence on physician and patient decisions
Brooke K. Coleman, Lesley H. Curtis, Mark W. Onaitis, Thomas A. D’Amico, Mark F. Berry
Diagnostic performance of cardiac magnetic resonance for the detection of acute cardiac allograft rejection: a systematic review and meta-analysis
Wei Lu, Jun Zheng, Xu-Dong Pan, Ming-Duo Zhang, Tie-Yuan Zhu, Bin Li, Li-Zhong Sun
Accelerated radiotherapy and concurrent chemotherapy for patients with contralateral central or mediastinal lung cancer relapse after pneumonectomy
Christoph Pöttgen, Jehad Abu Jawad, Eleni Gkika, Lutz Freitag, Wolfgang Lübcke, Stefan Welter, Thomas Gauler, Martin Schuler, Wilfried Ernst Erich Eberhardt, Georgios Stamatis, Martin Stuschke
CT features of lung scar cancer
Feng Gao, Xiaojun Ge, Ming Li, Xiangpeng Zheng, Li Xiao, Guozhen Zhang, Yanqing Hua
Correlation between familial cancer history and epidermal growth factor receptor mutations in Taiwanese never smokers with nonsmall cell lung cancer: a case-control study
Po-Chung Cheng, Yun-Chung Cheng
Effect of a combined anti-thrombotic therapy of thrombosis on prosthetic heart valves
Wei Wei, Taiming Dong, Zhichao Zheng, Shuping Huang
PET-CT guided curative conformal radiation therapy in limited stage small cell lung cancer
Sukran Ulger, Nilgun Yilmaz Demirci, Ercan Aydinkarahaliloglu, Fatih Caglar Kahraman, Ozlem Ozmen, Yurdanur Erdogan, Eren Cetin, Emine Avci, Mustafa Cengiz
Circulating miR-499 are novel and sensitive biomarker of acute myocardial infarction
Lizhu Zhang, Xi Chen, Tong Su, Heng Li, Qiang Huang, Dan Wu, Chengjian Yang, Zhijun Han
Therapy in stable chronic obstructive pulmonary disease patients with pulmonary hypertension: a systematic review and meta-analysis
Xuesong Chen, Shaowen Tang, Kouying Liu, Qinling Li, Hui Kong, Xiaoning Zeng, Weiping Xie, Hong Wang
Efficacy and safety of endobronchial valves for advanced emphysema: a meta analysis
Hua Liu, Meng Xu, Yiqun Xie, Jie Gao, Songshi Ni
Prognostic value of different scoring models in patients with multiple organ dysfunction syndrome associated with acute COPD exacerbation
Kun Xiao, Chao Guo, Longxiang Su, Peng Yan, Xin Li, Lixin Xie
Impact of body mass index on survival of esophageal squamous carcinoma patients in southern China
Chao Ren, Xiu-Yu Cai, Miao-Zhen Qiu, De-Shen Wang, Feng-Hua Wang, Hui-Yan Luo, Rui-Hua Xu
Impact of metformin use on survival in locally-advanced, inoperable non-small cell lung cancer treated with definitive chemoradiation
Inaya Ahmed, Adam Ferro, Alan Cohler, John Langenfeld, Sujani G. Surakanti, Joseph Aisner, Wei Zou, Bruce G. Haffty, Salma K. Jabbour
The efficacy and safety of prone positioning in adults patients with acute respiratory distress syndrome: a meta-analysis of randomized controlled trials
So Young Park, Hyun Jung Kim, Kwan Ha Yoo, Yong Bum Park, Seo Woo Kim, Seok Jeong Lee, Eun Kyung Kim, Jung Hyun Kim, Yee Hyung Kim, Ji-yong Moon, Kyung Hoon Min, Sung Soo Park, Jinwoo Lee, Chang-Hoon Lee, Jinkyeong Park, Min Kwang Byun, Sei Won Lee, ChinKook Rlee, Ji Ye Jung, Yun Su Sim
Antioxidant and lipid-regulating effects of probucol combined with atorvastatin in patients with acute coronary syndrome
Yu-Song Guo, Cai-Xia Wang, Jian Cao, Jin-Liao Gao, Xiao Zou, Yi-Hong Ren, Li Fan
Epidemiology of carbapenem resistant Enterobacteriaceae (CRE) during 2000-2012 in Asia
Yanling Xu, Bing Gu, Mao Huang, Haiyan Liu, Ting Xu, Wenying Xia, Tong Wang
Clinical characteristics and survival in idiopathic pulmonary fibrosis and connective tissue disease-associated usual interstitial pneumonia
Esam H. Alhamad
Assessment of the usefulness of video-assisted thoracoscopic surgery in patients with non-tuberculous thoracic empyema
Heesung Lee, Sangmyeon Park, Hoseung Shin, Kunil Kim
Ginsenoside metabolite compound K enhances the efficacy of cisplatin in lung cancer cells
Yang Li, Tong Zhou, Chengyuan Ma, Weiwei Song, Jian Zhang, Zhenxiang Yu
Clinical outcomes of cyberknife stereotactic radiosurgery for lung metastases
Zhen Wang, Qing-Tao Kong, Jing Li, Xin-Hu Wu, Bing Li, Ze-Tian Shen, Xi-Xu Zhu, Yong Song
Effects of bronchoscopic lung volume reduction using transbronchial infusion of autologous blood and thrombin in patients with severe chronic obstructive pulmonary disease
Yasuyuki Mizumori, Yoshiro Mochiduki, Yasuharu Nakahara, Tetsuji Kawamura, Shin Sasaki, Akie Morimoto, Hiroaki Tsukamoto
Methylated APC and RASSF1A in multiple specimens contribute to the differential diagnosis of patients with undetermined solitary pulmonary nodules
Li Gao, Erfu Xie, Tongfu Yu, Dan Chen, Lixia Zhang, Bingfeng Zhang, Fang Wang, Jian Xu, Peijun Huang, Xisheng Liu, Bingliang Fang, Shiyang Pan
Variability in the anti-tumor effect of tegafur-uracil depending on histologic types of lung cancer
Bo-Ram Lee, Jin-Yeong Yu, Seong-Hoon Yoon, Hee-Jung Ban, Yong-Soo Kwon, In-Jae Oh, Kyu-Sik Kim, Yu-Il Kim, Sung-Chul Lim, Young-Chul Kim
Utility of EBUS-TBNA for diagnosis of mediastinal tuberculous lymphadenitis: a multicentre Australian experience
James Geake, Gary Hammerschlag, Phan Nguyen, Peter Wallbridge, Grant A. Jenkin, Tony M. Korman, Barton Jennings, Douglas F. Johnson, Louis B. Irving, Michael Farmer, Daniel P. Steinfort
Reconstruction techniques for hypopharyngeal and cervical esophageal carcinoma
Ming Jiang, Xiaotian He, Duoguang Wu, Yuanyuan Han, Hongwei Zhang, Minghui Wang
Evaluation of the efficacy and safety of anti-PD-1 and anti-PD-L1 antibody in the treatment of non-small cell lung cancer (NSCLC): a meta-analysis
Minghan Jia, Weijiao Feng, Shiyang Kang, Yaxiong Zhang, Jianfei Shen, Jiaxi He, Long Jiang, Wei Wang, Zhihua Guo, Guilin Peng, Gang Chen, Jianxing He, Wenhua Liang
Clinicopathological and prognostic significance of programmed cell death ligand1 (PD-L1) expression in patients with non-small cell lung cancer: a meta-analysis
Zhen-Kui Pan, Feng Ye, Xuan Wu, Han-Xiang An, Jing-Xun Wu
Changes in peripheral CD19+Foxp3+ and CD19+TGFβ+ regulatory B cell populations in rheumatoid arthritis patients with interstitial lung disease
Yingying Guo, Xiaomei Zhang, Muting Qin, Xiaofei Wang
A meta-analysis comparing hyperfractionated vs. conventional fractionated radiotherapy in non-small cell lung cancer
Weisan Zhang, Qian Liu, Xifeng Dong, Ping Lei

Surgical Technique

Video-assisted thoracic surgery resection of rib osteophytes
Zhiyong Su, Yuqin Bai, Yilei Zhang, Baihan Su, Tianshuo Jiang, Xin Zhao, Hongliang Bian, Bo Zhao
Uniportal video-assisted thoracoscopic left upper lobectomy under spontaneous ventilation
Diego Gonzalez-Rivas, Ricardo Fernandez, Mercedes de la Torre, Cesar Bonome
Video-assisted thoracoscopic double sleeve lobectomy: a lived video in a nationwide academic conference
Jun Huang, Yuan Qiu, Xin Xu, Yidong Wang, Lixia Zhong, Hanzhang Chen, Jianxing He

Review Article

Acute exacerbation of idiopathic pulmonary fibrosis—a review of current and novel pharmacotherapies
Maya M. Juarez, Andrew L. Chan, Andrew G. Norris, Brian M. Morrissey, Timothy E. Albertson
Etiology and management of spontaneous haemothorax
Davide Patrini, Nikolaos Panagiotopoulos, Jonathan Pararajasingham, Lasha Gvinianidze, Yassir Iqbal, David R. Lawrence

Cardiac Transplantation in Europe (Guest Editor: Martin Schweiger)1

Considerations for patients awaiting heart transplantation— Insights from the UK experience
Guy A. MacGowan, David S. Crossland, Asif Hasan, Stephan Schueler
Long-term continuous-flow left ventricular assist devices (LVAD) as bridge to heart transplantation
Matteo Pozzi, Raphaël Giraud, Piergiorgio Tozzi, Karim Bendjelid, Jacques Robin, Philippe Meyer, Jean François Obadia, Carlo Banfi
International collaboration and organ exchange in Switzerland
Julius Weiss, Melanie Kocher, Franz F. Immer
Long-term outcome following heart transplantation: current perspective
Markus J. Wilhelm
Pediatric heart transplantation
Martin Schweiger, Brian Stiasny, Hitendu Dave, Anna Cavigelli-Brunner, Christian Balmer, Oliver Kretschmar, Christoph Bürki, Dietrich Klauwer, Michael Hübler

Case Report

Anaplastic lymphoma kinase-positive lung adenocarcinoma patient with development of sick sinus syndrome while on targeted treatment with crizotinib
Hao Jiang, Mei-Mei Li, Shu-Xian Jin
Successful removal of a giant pulmonary hamartoma coexisting with an anomalous common pulmonary venous trunk
Hui Shi, Zhong-Xi Niu, Jun Peng, Yu-Shang Yang, Long-Qi Chen
Primary pulmonary cancer colliding with metastatic choriocarcinoma
Zheng Wang, Jingwen Si, Jingwei Liu
Aberrant aneurysm of adult-type pulmonary sequestration: report of a case
Tomoki Shibano, Shunsuke Endo, Kenji Tetsuka, Tsutomu Saito, Nobuyuki Kanai, Takashi Yashiro
Malignant pheochromocytoma with lung metastasis after right adrenalectomy for pheochromocytoma eleven years ago
Won Suk, Jong Yoon Park, Mee Sook Roh, Pil Jo Choi
Coinfection of Strongyloides stercoralis and Aspergillus found in bronchoalveolar lavage fluid from a patient with stubborn pulmonary symptoms
Jie Guo, Yi Sun, Yanru Man, Xiaochun Huang, Qin Qin, Daoyin Zhou, Anmei Deng
Paravertebral mediastinal Mullerian cyst resected by video assisted thoracoscopic surgery
Soon-Ho Chon, Ui Jae Im, Dong Seop Song
Double lung point in an 18-month-old child: a case report and literature review
Zhongheng Zhang
Flexible bronchoscopic excision of a tracheal mass under extracorporeal membrane oxygenation
Jae Jun Kim, Seok Whan Moon, Yong Hwan Kim, Si Young Choi, Seong Cheol Jeong

Short Communication

Thoracoscopic anatomical resection of congenital lung malformations in adults
Lidia Macias, Amaia Ojanguren, Julien Dahdah, Dominique Gossot


1. The series “Cardiac Transplantation in Europe” was commissioned by the Editorial office, Journal of Thoracic Disease without any sponsorship or funding. Martin Schweiger served as the unpaid Guest Editor for the series.

2. The series “Statistics Corner” was commissioned by the Editorial office, Journal of Thoracic Disease without any sponsorship or funding. Luca Bertolaccini served as the unpaid Guest Editor for the series.

3. The series “ICC COLUMN: The Voice of the Patient” was commissioned by the Editorial office, Journal of Thoracic Disease without any sponsorship or funding. Lawrence Grouse served as the unpaid Guest Editor for the series.